Search Results - "Krzystyniak, Joanna"

Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestine by Holik, Aliaksei Z, Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T, Metzger, Daniel, Shorning, Boris Y, Clarke, Alan R

“…Tumourigenesis within the intestine is potently driven by deregulation of the Wnt pathway, a process epigenetically regulated by the chromatin remodelling…”
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Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue‐specific manner by Holik, Aliaksei Z., Krzystyniak, Joanna, Young, Madeleine, Richardson, Kirsty, Jardé, Thierry, Chambon, Pierre, Shorning, Boris Y., Clarke, Alan R.

“…Brg1 is a chromatin remodeling factor involved in mediation of a plethora of signaling pathways leading to its participation in various physiological processes…”
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A phase 2 randomized open-label study of oral darolutamide monotherapy vs. androgen deprivation therapy in men with hormone-naive prostate cancer (EORTC-GUCG 1532) by Tombal, Bertrand F., Gomez-Veiga, Francisco, Gomez-Ferrer, Alvaro, López-Campos, Fernando, Ost, Piet, Roumeguere, Thierry Andre, Herrera-Imbroda, Bernardo, D'Hondt, Lionel A., Quivrin, Magali, Gontero, Paolo, Villà, Salvador, Khaled, Hussein Mustafa, Fournier, Beatrice, Krzystyniak, Joanna, Pretzenbacher, Yassin, Erkol, Hazal, Loriot, Yohann

“…160 Background: Darolutamide is androgen-receptor (AR) inhibitor with low blood–brain barrier penetration and limited potential for clinically relevant…”
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Radiotherapy Combined with a Radiosensitizer for Bacillus Calmette-Guérin–unresponsive Non–muscle-invasive Carcinoma In Situ Bladder Cancer: An Open-label, Single-arm, Multicenter, Phase 2 European Organisation for Research and Treatment of Cancer Trial by Achard, Vérane, Fournier, Béatrice, D'Haese, David, Krzystyniak, Joanna, Tombal, Bertrand, Roupret, Morgan, Sargos, Paul, Dirix, Piet

“…Combining external beam radiotherapy with radiosensitizers offers a promising alternative to radical cystectomy for bacillus Calmette-Guérin (BCG)-unresponsive…”
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MitoQ Prevents Human Breast Cancer Recurrence and Lung Metastasis in Mice by Capeloa, Tania, Krzystyniak, Joanna, Rodriguez, Amanda Canas, Payen, Valéry L, Zampieri, Luca X, Pranzini, Erica, Derouane, Françoise, Vazeille, Thibaut, Bouzin, Caroline, Duhoux, François P, Murphy, Michael P, Porporato, Paolo E, Sonveaux, Pierre

“…In oncology, the occurrence of distant metastases often marks the transition from curative to palliative care. Such outcome is highly predictable for breast…”
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MitoQ Inhibits Human Breast Cancer Cell Migration, Invasion and Clonogenicity by Capeloa, Tania, Krzystyniak, Joanna, d'Hose, Donatienne, Canas Rodriguez, Amanda, Payen, Valery L, Zampieri, Luca X, Van de Velde, Justine A, Benyahia, Zohra, Pranzini, Erica, Vazeille, Thibaut, Fransolet, Maude, Bouzin, Caroline, Brusa, Davide, Michiels, Carine, Gallez, Bernard, Murphy, Michael P, Porporato, Paolo E, Sonveaux, Pierre

“…To successfully generate distant metastases, metastatic progenitor cells must simultaneously possess mesenchymal characteristics, resist to anoïkis, migrate…”
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A Phase 2 Randomized Open-label Study of Oral Darolutamide Monotherapy Versus Androgen Deprivation Therapy in Men with Hormone-sensitive Prostate Cancer (EORTC-GUCG 1532) by Tombal, Bertrand F., Gomez-Veiga, Francisco, Gomez-Ferrer, Alvaro, López-Campos, Fernando, Ost, Piet, Roumeguere, Thierry Andre, Herrera-Imbroda, Bernardo, D'Hondt, Lionel A., Quivrin, Magali, Gontero, Paolo, Villà, Salvador, Khaled, Hussein, Fournier, Beatrice, Musoro, Jammbe, Krzystyniak, Joanna, Pretzenbacher, Yassin, Loriot, Yohann

“…Darolutamide is a nonsteroidal androgen receptor (AR) antagonist with a unique molecular structure, distinct from other AR antagonists such as enzalutamide and…”
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Brg1 Loss Attenuates Aberrant Wnt-Signalling and Prevents Wnt-Dependent Tumourigenesis in the Murine Small Intestine: e1004453 by Holik, Aliaksei Z, Young, Madeleine, Krzystyniak, Joanna, Williams, Geraint T, Metzger, Daniel, Shorning, Boris Y, Clarke, Alan R

“…Tumourigenesis within the intestine is potently driven by deregulation of the Wnt pathway, a process epigenetically regulated by the chromatin remodelling…”
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Epigenetic modulation of intestinal homeostasis and tumorigenesis by brm swi/snf chromatin remodelling factor by Krzystyniak, Joanna

“…SWI/SNF chromatin remodelling complexes are one of the well-characterized cellular machineries capable of regulation of gene expression. Numerous lines of…”
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