Search Results - "Krzemiński, Patryk"
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The P2Y14 receptor activity in glioma C6 cells
Published in European journal of pharmacology (10-10-2008)“…In this study, we demonstrated the presence and the activity of the P2Y14 receptor in glioma C6 cells. We found that P2Y14 could exist in two forms, highly…”
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2
The protective effect of silver nanoparticles' on epithelial cornea cells against ultraviolet is accompanied by changes in calcium homeostasis and a decrease of the P2X7 and P2Y2 receptors
Published in Biomedicine & pharmacotherapy (01-01-2024)“…The aim of the study was to evaluate the effect of silver nanoparticles hydrocolloids (AgNPs) on human corneal epithelial cells. Epithelial cells form the…”
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3
Factors determining the sensitivity to proteasome inhibitors of multiple myeloma cells
Published in Frontiers in pharmacology (04-03-2024)“…Multiple myeloma is an incurable cancer that originates from antibody-producing plasma cells. It is characterized by an intrinsic ability to produce large…”
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Do Small Molecules Activate the TrkB Receptor in the Same Manner as BDNF? Limitations of Published TrkB Low Molecular Agonists and Screening for Novel TrkB Orthosteric Agonists
Published in Pharmaceuticals (Basel, Switzerland) (21-07-2021)“…TrkB is a tyrosine kinase receptor that is activated upon binding to brain-derived neurotrophic factor (BDNF). To date, the search for low-molecular-weight…”
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Molecular Mechanisms of p53 Deregulation in Cancer: An Overview in Multiple Myeloma
Published in International journal of molecular sciences (30-11-2016)“…The p53 pathway is inactivated in the majority of human cancers. Although this perturbation frequently occurs through the mutation or deletion of p53 itself,…”
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Zebularine-induced myeloma cell death is accompanied by decreased c-Myc expression
Published in Cellular oncology (Dordrecht) (01-08-2020)“…Purpose Epigenetic therapies have proven to be clinically effective in several hematological malignancies. Here, we aimed to evaluate the effect of a…”
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Restoration of microRNA-214 expression reduces growth of myeloma cells through positive regulation of P53 and inhibition of DNA replication
Published in Haematologica (Roma) (01-04-2013)“…MicroRNA have been demonstrated to be deregulated in multiple myeloma. We have previously reported that miR-214 is down-regulated in multiple myeloma compared…”
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Factors Regulating microRNA Expression and Function in Multiple Myeloma
Published in Non-coding RNA (16-01-2019)“…Intensive research has been undertaken during the last decade to identify the implication of microRNAs (miRNAs) in the pathogenesis of multiple myeloma (MM)…”
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Post-transcriptional Modifications Contribute to the Upregulation of Cyclin D2 in Multiple Myeloma
Published in Clinical cancer research (01-01-2016)“…Dysregulation of one of the three D-cyclin genes has been observed in virtually all multiple myeloma tumors. The mechanisms by which CCND2 is upregulated in a…”
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10
DEPTOR maintains plasma cell differentiation and favorably affects prognosis in multiple myeloma
Published in Journal of hematology and oncology (18-04-2017)“…The B cell maturation process involves multiple steps, which are controlled by relevant pathways and transcription factors. The understanding of the final…”
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11
Phenotypic, genomic and functional characterization reveals no differences between CD138++ and CD138low subpopulations in multiple myeloma cell lines
Published in PloS one (21-03-2014)“…Despite recent advances in the treatment of multiple myeloma (MM), it remains an incurable disease potentially due to the presence of resistant myeloma cancer…”
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12
Is MLC phosphorylation essential for the recovery from ROCK inhibition in glioma C6 cells?
Published in Acta biochimica polonica (01-01-2011)“…Inhibition of Rho-associated protein kinase (ROCK) activity in glioma C6 cells induces changes in actin cytoskeleton organization and cell morphology similar…”
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13
P2Y(1) and P2Y(12) receptor cross-talk in calcium signalling: Evidence from nonstarved and long-term serum-deprived glioma C6 cells
Published in Purinergic signalling (01-06-2007)“…The current work presents results of experiments on the calcium response evoked by the stimulation by extracellular nucleotides occurring in control,…”
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14
Expression and functional characterization of P2Y1 and P2Y12 nucleotide receptors in long‐term serum‐deprived glioma C6 cells
Published in The FEBS journal (01-04-2007)“…We characterized the expression and functional properties of the ADP‐sensitive P2Y1 and P2Y12 nucleotide receptors in glioma C6 cells cultured in medium devoid…”
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15
The P2Y 14 receptor activity in glioma C6 cells
Published in European journal of pharmacology (2008)“…In this study, we demonstrated the presence and the activity of the P2Y 14 receptor in glioma C6 cells. We found that P2Y 14 could exist in two forms, highly…”
Get full text
Journal Article -
16
Modulation of ERK1/2 activity is crucial for sphingosine-induced death of glioma C6 cells
Published in Acta biochimica polonica (01-01-2005)“…In this study the contribution of the ERK1/2 pathway to sphingosine-induced death and morphological changes of the actin cytoskeleton in glioma C6 cells was…”
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17
P2 nucleotide receptors on C2C12 satellite cells
Published in Purinergic signalling (01-09-2005)“…In developing muscle cells environmental stimuli transmitted by purines binding to the specific receptors are crucial proliferation regulators. C2C12 myoblasts…”
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18
Effect of Rho-associated kinase inhibition on actin cytoskeleton structure and calcium response in glioma C6 cells
Published in Acta biochimica polonica (01-01-2006)“…The role of actin cytoskeleton functional state in glioma C6 cell morphology and calcium signaling was investigated through modification of myosin II activity…”
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19
Expression and functional characterization of P2Y 1 and P2Y 12 nucleotide receptors in long‐term serum‐deprived glioma C6 cells
Published in The FEBS journal (01-04-2007)“…We characterized the expression and functional properties of the ADP‐sensitive P2Y 1 and P2Y 12 nucleotide receptors in glioma C6 cells cultured in medium…”
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20
A Comprehensive Assessment of the Biocompatibility and Safety of Diamond Nanoparticles on Reconstructed Human Epidermis
Published in Materials (01-08-2023)“…Diamond nanoparticles, also known as nanodiamonds (NDs), exhibit remarkable, awe-inspiring properties that make them suitable for various applications in the…”
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