Search Results - "Kryda, Kristina"

Moxidectin: heartworm disease prevention in dogs in the face of emerging macrocyclic lactone resistance by Savadelis, Molly D, McTier, Tom L, Kryda, Kristina, Maeder, Steven J, Woods, Debra J

“…Heartworm (Dirofilaria immitis) disease continues to increase and spread, remaining one of the most important and pathogenic parasitic diseases of dogs,…”
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A blinded, randomized, placebo-controlled trial of the safety of lokivetmab (ZTS-00103289), a caninized anti-canine IL-31 monoclonal antibody in client-owned dogs with atopic dermatitis by Michels, Gina M., Walsh, Kelly F., Kryda, Kristina A., Mahabir, Sean P., Walters, Rodney R., Hoevers, Jacquelien D., Martinon, Olivier M.

“…Background Lokivetmab (ZTS‐00103289) is a caninized anti‐canine IL‐31 monoclonal antibody that has demonstrated efficacy in reducing pruritus associated with…”
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Safety and efficacy of a novel oral chewable combination tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against natural flea infestations in client-owned dogs in the USA by Kryda, Kristina, Mahabir, Sean P, Inskeep, Tammy, Rugg, Jady

“…One randomized, controlled clinical field study was conducted in 18 general veterinary practices throughout the USA to evaluate the safety and efficacy of a…”
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Evaluation of the speed of kill of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced infestations of Ixodes scapularis on dogs by Holzmer, Susan, Kryda, Kristina, Mahabir, Sean P, Everett, William

“…The black-legged (or deer) tick, Ixodes scapularis, commonly infests dogs in the USA and is the vector of important zoonotic pathogens, including Borrelia…”
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ProHeart® 12, a moxidectin extended-release injectable formulation for prevention of heartworm (Dirofilaria immitis) disease in dogs in the USA for 12 months by McTier, Tom L, Kryda, Kristina, Wachowski, Martha, Mahabir, Sean, Ramsey, Deborah, Rugg, Doug, Mazaleski, Mark, Therrien, Carol, Adams, Eric, Wolff, T, Bowman, Dwight D

“…The efficacy of an extended-release injectable moxidectin (0.5 mg/kg) suspension (ProHeart® 12) (PH 12) in preventing the development of Dirofilaria immitis in…”
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Preventive efficacy of oral moxidectin at various doses and dosage regimens against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs by McTier, Tom L, Six, Robert H, Pullins, Aleah, Chapin, Sara, Kryda, Kristina, Mahabir, Sean P, Woods, Debra J, Maeder, Steven J

“…Moxidectin has previously shown limited efficacy (≤ 44.4%) against confirmed macrocyclic lactone (ML)-resistant Dirofilaria immitis strains at 3 µg/kg after…”
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Efficacy of a new oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced ascarid infections in dogs by Becskei, Csilla, Kryda, Kristina, Thys, Mirjan, Holzmer, Susan, Bowersock, Laurel, Fernandes, Tiago, Meyer, Leon, Reinemeyer, Craig, Mahabir, Sean P

“…Ascarid infections are among the most prevalent intestinal parasitic infections occurring in dogs around the world, with Toxocara canis and Toxascaris leonina…”
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Efficacy of Simparica Trio™, a novel chewable tablet containing sarolaner, moxidectin and pyrantel, against induced hookworm infections in dogs by Becskei, Csilla, Thys, Mirjan, Kryda, Kristina, Meyer, Leon, Martorell, Susanna, Geurden, Thomas, Dreesen, Leentje, Fernandes, Tiago, Mahabir, Sean P

“…Ancylostomatids ('hookworms') are among the most important zoonotic nematode parasites infecting dogs worldwide. Ancylostoma caninum and Uncinaria stenocephala…”
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A review of moxidectin vs. other macrocyclic lactones for prevention of heartworm disease in dogs with an appraisal of two commercial formulations by Mwacalimba, Kennedy, Sheehy, Jenifer, Adolph, Christopher, Savadelis, Molly, Kryda, Kristina, Poulsen Nautrup, Barbara

“…Macrocyclic lactones (MLs) are the only drug class currently licensed for heartworm disease prophylaxis. Macrocyclic lactones kill third- and fourth-stage…”
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Comparative preventive efficacy of ProHeart ® 12, Heartgard ® Plus and Interceptor ® Plus against a macrocyclic lactone-resistant strain (JYD-34) of heartworm (Dirofilaria immitis) in dogs by McTier, Tom L, Holzmer, Susan, Kryda, Kristina, Mahabir, Sean, McCall, John W, Trombley, Jami, Maeder, Steven J

“…The current studies compared ProHeart 12, Heartgard Plus and Interceptor Plus for preventive efficacy against JYD-34, a macrocyclic lactone (ML)-resistant…”
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Preventive efficacy of six monthly oral doses of Simparica Trio ® , Heartgard ® Plus, and Interceptor ® Plus against a macrocyclic lactone-resistant strain (ZoeLA) of heartworm (Dirofilaria immitis) in dogs by Myers, Jamie A E, Holzmer, Susan, McCall, John W, Mahabir, Sean P, McTier, Tom L, Maeder, Steven J, Kryda, Kristina

“…Administration of four to six consecutive monthly doses of 24 µg/kg moxidectin alone shows high effectiveness in preventing the maturation of macrocyclic…”
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Field efficacy and safety of a novel oral chewable tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against naturally acquired gastrointestinal nematode infections in dogs presented as veterinary patients in Europe and the USA by Becskei, Csilla, Kryda, Kristina, Fias, Daphne, Follis, Stacey L, Wozniakiewicz, Magda, Mahabir, Sean P, Farkas, Robert

“…Gastrointestinal nematodes are parasites that commonly infect dogs, and infections can be subclinical or may cause considerable clinical disease. Some species…”
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Laboratory and field studies to investigate the efficacy of a novel, orally administered combination product containing moxidectin, sarolaner and pyrantel for the prevention of heartworm disease (Dirofilaria immitis) in dogs by Kryda, Kristina, Six, Robert H, Walsh, Kelly F, Holzmer, Susan J, Chapin, Sara, Mahabir, Sean P, Myers, Melanie, Inskeep, Tammy, Rugg, Jady, Cundiff, Blair, Pullins, Aleah, Ulrich, Michael, McCall, John W, McTier, Tom L, Maeder, Steven J

“…Dirofilaria immitis is a filarial parasite of dogs that can cause serious or fatal cardiopulmonary disease. Three studies were conducted to evaluate the…”
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Efficacy of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) against induced infestations of five common tick species infesting dogs in the USA by Kryda, Kristina, Mahabir, Sean P, Chapin, Sara, Holzmer, Susan J, Bowersock, Laurel, Everett, William R, Riner, John, Carter, Lori, Young, David

“…The efficacy of a novel oral combination product, Simparica Trio™, containing sarolaner, moxidectin and pyrantel was evaluated against five tick species that…”
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Laboratory studies evaluating the efficacy of a novel orally administered combination product containing sarolaner, moxidectin and pyrantel (Simparica Trio™) for the treatment and control of flea infestations on dogs by Kryda, Kristina, Mahabir, Sean P, Carter, Lori, Everett, William R, Young, David R, Meyer, Leon, Thys, Mirjan, Chapin, Sara, Holzmer, Susan J, Becskei, Csilla

“…Five studies were conducted to evaluate a novel oral combination tablet containing sarolaner, moxidectin and pyrantel (Simparica Trio™), for efficacy against…”
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Preventive efficacy of four or six monthly oral doses of 24 µg/kg moxidectin compared to six monthly doses of Heartgard® Plus or Interceptor® Plus against macrocyclic lactone-resistant heartworm (Dirofilaria immitis) strains in dogs by Kryda, Kristina, Holzmer, Susan, Everett, William R, McCall, John W, Mahabir, Sean P, McTier, Tom L, Maeder, Steven J

“…Recent reports indicated that increasing the monthly oral dosage and the number of consecutive monthly doses of moxidectin improved the efficacy against…”
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Safety of an extended-release injectable moxidectin suspension formulation (ProHeart ® 12) in dogs by Krautmann, Matthew J, Mahabir, Sean, Fielder, Ann, Collard, Wendy, Wolthuis, Tracie L, Esch, Kevin, Morton, Tracy, Alleman, Kent, Luo, Laibin, McCandless, Erin, Nederveld, Steven, Kryda, Kristina, Carroll, Ryan, Boucher, Joseph F

“…The safety of ProHeart® 12 (PH 12; extended-release injectable suspension; 10% moxidectin in glyceryl tristearate microspheres) was evaluated in four studies…”
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Insecticidal activity of Simparica and Simparica Trio against Aedes aegypti in dogs by Geurden, Thomas, Chapin, Sara, McCall, John W, Mansour, Abdelmoneim, Mahabir, Sean P, Kryda, Kristina, McTier, Tom

“…Aedes aegypti is one of the main species responsible for the transmission of mosquito-borne pathogens worldwide. The isoxazoline Sarolaner has excellent…”
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Preventive efficacy of six monthly oral doses of Simparica Trio[R], Heartgard[R] Plus, and Interceptor[R] Plus against a macrocyclic lactone-resistant strain in dogs by Myers, Jamie A. E, Holzmer, Susan, McCall, John W, Mahabir, Sean P, McTier, Tom L, Maeder, Steven J, Kryda, Kristina

“…Administration of four to six consecutive monthly doses of 24 [micro]g/kg moxidectin alone shows high effectiveness in preventing the maturation of macrocyclic…”
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Comparative preventive efficacy of ProHeart[R] 12, Heartgard[R] Plus and Interceptor[R] Plus against a macrocyclic lactone-resistant strain in dogs by McTier, Tom L, Holzmer, Susan, Kryda, Kristina, Mahabir, Sean, McCall, John W, Trombley, Jami, Maeder, Steven J

“…The current studies compared ProHeart.sup.[R] 12, Heartgard.sup.[R] Plus and Interceptor.sup.[R] Plus for preventive efficacy against JYD-34, a macrocyclic…”
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