Search Results - "Krutovskikh, V"

Differential effect of subcellular localization of communication impairing gap junction protein connexin43 on tumor cell growth in vivo by KRUTOVSKIKH, V. A, TROYANOVSKY, S. M, PICCOLI, C, TSUDA, H, ASAMOTO, M, YAMASAKI, H

“…There is a large body of evidence suggesting the connexin gap junction proteins appear to act as tumor suppressors, and their tumor inhibitory effect is…”
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New insights in oncology: epigenetics and cancer stem cells by Krutovskikh, V, Partensky, C

“…Cancer is a multi-etiologic, multistage disease with a prevalent genetic component, which happens when a large number of genes, critical for cell growth,…”
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Inhibition of rat liver gap junction intercellular communication by tumor-promoting agents in vivo. Association with aberrant localization of connexin proteins by Krutovskikh, V A, Mesnil, M, Mazzoleni, G, Yamasaki, H

“…Gap junctional intercellular communication is believed to play an important role in the maintenance of tissue homeostasis, and disruption of it has been…”
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The role of gap junctional intercellular communication (GJIC) disorders in experimental and human carcinogenesis by Krutovskikh, V, Yamasaki, H

“…There is a growing body of evidence supporting the etiologic implication of gap junctional intercellular communication disorders in carcinogenesis. Substantial…”
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Assessment of Transformed Properties In Vitro and of Tumorigenicity In Vivo in Primary Keratinocytes Cultured for Epidermal Sheet Transplantation by Desanlis, A., Thépot, A., Venet, E., Thivillier, L., Justin, V., Morel, A. P., DeFraipont, F., Till, M., Krutovskikh, V., Tommasino, M., Damour, O., Hainaut, Pierre

“…Epidermal keratinocytes are used as a cell source for autologous and allogenic cell transplant therapy for skin burns. The question addressed here is to…”
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Nouvelles perspectives en oncologie : épigénétique et cellules souches cancéreuses by Krutovskikh, V., Partensky, C.

“…Le cancer est une maladie aux étiologies multiples, aux stades évolutifs extrêmement variés, qui présente une composante génétique dominante. Un grand nombre…”
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Patterns of expression of keratin 17 in human epithelia: dependency on cell position by TROYANOVSKY, S. M, GUELSTEIN, V. I, TCHIPYSHEVA, T. A, KRUTOVSKIKH, V. A, BANNIKOV, G. A

“…By immunomorphology, using keratin 17-specific monoclonal antibody, it has been shown that this keratin is expressed only in the basal cells of a group of…”
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Altered homologous and heterologous gap-junctional intercellular communication in primary human liver tumors associated with aberrant protein localization but not gene mutation of connexin 32 by Krutovskikh, V, Mazzoleni, G, Mironov, N, Omori, Y, Aguelon, A M, Mesnil, M, Berger, F, Partensky, C, Yamasaki, H

“…Gap-junctional intercellular communication (GJIC) in 20 primary human liver tumors with different degrees of malignancy has been studied at the functional and…”
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Identification of the Plakoglobin-Binding Domain in Desmoglein and Its Role in Plaque Assembly and Intermediate Filament Anchorage by Troyanovsky, Sergey M., Troyanovsky, Regina B., Eshkind, Leonid G., Krutovskikh, Vladimir A., Leube, Rudolf E., Franke, Werner W.

“…The carboxyterminal cytoplasmic portions (tails) of desmosomal cadherins of both the desmoglein (Dsg) and desmocollin type are integral components of the…”
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Sequential changes of gap-junctional intercellular communications during multistage rat liver carcinogenesis: direct measurement of communication in vivo by Krutovskikh, V A, Oyamada, M, Yamasaki, H

“…We have developed a simple method to measure gap-junctional intercellular communication (GJIC), by means of microinjection/dye transfer assay, in liver slices…”
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Inhibition of intrinsic gap-junction intercellular communication and enhancement of tumorigenicity of the rat bladder carcinoma cell line BC31 by a dominant-negative connexin 43 mutant by Krutovskikh, Vladimir A., Yamasaki, Hiroshi, Tsuda, Hiroyuki, Asamoto, Makoto

“…The tumor‐suppressive property of the connexin gap‐junction proteins was postulated from the fact that their function of cell coupling is impaired in most…”
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Connexin 43, but not connexin 32, is mutated at advanced stages of human sporadic colon cancer by Dubina, Michael V, Iatckii, Nikolay A, Popov, Dimitrii E, Vasil'ev, Sergei V, Krutovskikh, Vladimir A

“…The membrane-spanning connexin proteins form microscopic intercellular channels that directly connect the cytoplasms of adjacent cells and as such have been…”
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Human connexin 37 is polymorphic but not mutated in tumors by KRUTOVSKIKH, V, MIRONOV, N, YAMASAKI, H

“…Connexins are phylogenetically conserved proteins responsible for gap junctional intercellular communication (GJIC). In tumours, GJIC is frequently disrupted…”
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Distribution of individual components of basement membrane in human colon polyps and adenocarcinomas as revealed by monoclonal antibodies by Ljubimov, A V, Bartek, J, Couchman, J R, Kapuller, L L, Veselov, V V, Kovarik, J, Perevoshchikov, A G, Krutovskikh, V A

“…Double-label immunofluorescence was used to monitor basement-membrane composition and integrity in 22 human colon polyps, 36 adenocarcinomas and 2 metastases…”
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Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43 by Upham, Brad L., Suzuki, Junji, Chen, Gang, Wang, Yurong, McCabe, Laura R., Chang, Chia-Cheng, Krutovskikh, Vladimir A., Yamasaki, Hiroshi, Trosko, James E.

“…Gap junctional intercellular communication (GJIC) maintains normal growth and differentiation of cells in a tissue. The intercellular molecules traversing gap…”
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Genetic and epigenetic changes of intercellular communication genes during multistage carcinogenesis by Yamasaki, H, Omori, Y, Zaidan-Dagli, M L, Mironov, N, Mesnil, M, Krutovskikh, V

“…During multistage carcinogenesis, the functions of several key genes involved in cell growth control must be damaged. Such genes include not only those…”
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Gap junctional intercellular communication and cell proliferation during rat liver carcinogenesis by Yamasaki, H, Krutovskikh, V, Mesnil, M, Columbano, A, Tsuda, H, Ito, N

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Lack of tumor-promoting effects of flavonoids: studies on rat liver preneoplastic foci and on in vivo and in vitro gap junctional intercellular communication by Chaumontet, C, Suschetet, M, Honikman-Leban, E, Krutovskikh, V A, Berges, R, Le Bon, A M, Heberden, C, Shahin, M M, Yamasaki, H, Martel, P

“…Possible tumor-promoting activity of four flavonoids, quercetin (QC), tangeretin (TG), flavone (FO), and flavanone (FN), was examined in a rat liver short-term…”
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The scientific and clinical value of molecular genetic changes in the intercellular gap junctions observed in colon cancer by Iaitskiĭ, N A, Dubina, M V, Vasil'ev, S V, Popov, D E, Krutovskikh, V A

“…Colon cancer is one of the most widespread pathologies with high mortality due to recurrence and metastasis. The molecular methods of diagnosis,…”
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Connexin gene mutations in human genetic diseases by Krutovskikh, Vladimir, Yamasaki, Hiroshi

“…Rapid advances in understanding the molecular biology of the gap junctional proteins — connexins (Cx) — have revealed that these proteins are indispensable for…”
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