Search Results - "Kruse, TA"

A genome-wide scan shows significant linkage between bipolar disorder and chromosome 12q24.3 and suggestive linkage to chromosomes 1p22-21, 4p16, 6q14-22, 10q26 and 16p13.3 by EWALD, H, FLINT, T, KRUSE, T. A, MORS, O

“…The present study reports a genomewide scan using linkage analysis for risk genes involved in bipolar disorder with 613 microsatellite markers including…”
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Alpha-cardiac actin is a novel disease gene in familial hypertrophic cardiomyopathy by Mogensen, J, Klausen, I C, Pedersen, A K, Egeblad, H, Bross, P, Kruse, T A, Gregersen, N, Hansen, P S, Baandrup, U, Borglum, A D

“…We identified the alpha-cardiac actin gene (ACTC) as a novel disease gene in a pedigree suffering from familial hypertrophic cardiomyopathy (FHC). Linkage…”
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Managerial discipline and corporate restructuring following performance declines by Denis, David J, Kruse, Timothy A

“…We examine the incidence of disciplinary events that reduce the control of current managers, and corporate restructuring among firms experiencing a large…”
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Possible gene dosage effect of glutathione-S-transferases on atopic asthma: Using real-time PCR for quantification of GSTM1 and GSTT1 gene copy numbers by Brasch-Andersen, Charlotte, Christiansen, Lene, Tan, Qihua, Haagerup, Annette, Vestbo, Jørgen, Kruse, Torben A.

“…Asthma is a complex genetic disorder characterized by chronic inflammation in the airways. As oxidative stress is a key component of inflammation, variations…”
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A genome-wide search for alleles and haplotypes associated with autism and related pervasive developmental disorders on the Faroe Islands by Lauritsen, M B, Als, T D, Dahl, H A, Flint, T J, Wang, A G, Vang, M, Kruse, T A, Ewald, H, Mors, O

“…The involvement of genetic factors in the etiology of autism has been clearly established. We undertook a genome-wide search for regions containing…”
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Asthma and atopy – a total genome scan for susceptibility genes by Haagerup, A., Bjerke, T., Schiøtz, P. O., Binderup, H. G., Dahl, R., Kruse, T. A.

“…Background:  Allergic asthma is an increasingly common disease of complex inheritance. Several studies have suggested candidate regions, but genetic…”
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Acute hypoxia induces upregulation of microRNA-210 expression in glioblastoma spheroids by Rosenberg, Thomassen, Jensen, SS, Larsen, MJ, Sørensen, KP, Hermansen, SK, Kruse, TA, Kristensen, BW

“…Tumor hypoxia and presence of tumor stem cells are related to therapeutic resistance and tumorigenicity in glioblastomas. The aim of the present study was…”
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Genetic Association Analysis of Human Longevity in Cohort Studies of Elderly Subjects: An Example of the PON1 Gene in the Danish 1905 Birth Cohort by Tan, Qihua, Christiansen, Lene, Bathum, Lise, Li, Shuxia, Kruse, Torben A, Christensen, Kaare

“…Although the case-control or the cross-sectional design has been popular in genetic association studies of human longevity, such a design is prone to false…”
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Atopic dermatitis: a total genome-scan for susceptibility genes by HAAGERUP, Annette, BJERKE, Torbjørn, SCHIØTZ, Peter Oluf, DAHL, Ronald, BINDERUP, Helle Glud, TAN, Qihua, KRUSE, Torben Arvid

“…Atopic dermatitis is one of the most common chronic diseases of childhood and closely related to other clinical manifestations of allergy. The incidence is…”
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Family based association analysis of the IL2 and IL15 genes in allergic disorders by CHRISTENSEN, Ulla, HAAGERUP, Annette, BINDERUP, Helle G, VESTBO, Jørgen, KRUSE, Torben A, BØRGLUM, Anders D

“…Allergic diseases affect an increasing number of individuals and are a major global health problem. A substantial genetic contribution in the aetiology of…”
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Serum protein profiling by miniaturized solid-phase extraction and matrix-assisted laser desorption/ionization mass spectrometry by Callesen, Anne K., Mohammed, Shabaz, Bunkenborg, Jakob, Kruse, Torben A., Cold, Søren, Mogensen, Ole, Christensen, Rene dePont, Vach, Werner, Jørgensen, Per E., Jensen, Ole N.

“…Serum profiling by matrix‐assisted laser desorption/ionization mass spectrometry (MALDI‐MS) holds promise as a clinical tool for early diagnosis of cancer and…”
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Genome wide scan using homozygosity mapping and linkage analyses of a single pedigree with affective disorder suggests oligogenic inheritance by Ewald, Henrik, Kruse, Torben A., Mors, Ole

“…The present study reports results from a genome scan on a family with bipolar affective disorder in which the parents are first cousins and four of the…”
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Highly significant linkage to chromosome 3q13.31 for rhinitis and related allergic diseases by Brasch-Andersen, C, Haagerup, A, Børglum, A D, Vestbo, J, Kruse, T A

“…Background: Allergic diseases such as asthma and rhinitis have closely related phenotypes and often occur with atopy. They show strong familial and…”
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Mutational screening and association study of glutamate decarboxylase 1 as a candidate susceptibility gene for bipolar affective disorder and schizophrenia by Lundorf, M.D., Buttenschøn, H.N., Foldager, L., Blackwood, D.H.R., Muir, W.J., Murray, V., Pelosi, A.J., Kruse, T.A., Ewald, H., Mors, O.

“…Recent evidence from postmortem studies suggests that GAD1 encoding the gamma‐aminobutyric acid (GABA) synthetic enzyme GAD67 is a functional candidate…”
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Genetic dissection of gene expression observed in whole blood samples of elderly Danish twins by QIHUA TAN, CHRISTENSEN, Kaare, CHRISTIANSEN, Lene, FREDERIKSEN, Henrik, BATHUM, Lise, DAHLGAARD, Jesper, KRUSE, Torben A

“…The microarray technique is an important tool in gene expression analysis to study the activities of thousands of genes measured by their transcript levels…”
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Nordic collaborative study of the BARD1 Cys557Ser allele in 3956 patients with cancer: enrichment in familial BRCA1/BRCA2 mutation-negative breast cancer but not in other malignancies by Karppinen, S-M, Barkardottir, R B, Backenhorn, K, Sydenham, T, Syrjäkoski, K, Schleutker, J, Ikonen, T, Pylkäs, K, Rapakko, K, Erkko, H, Johannesdottir, G, Gerdes, A-M, Thomassen, M, Agnarsson, B A, Grip, M, Kallioniemi, A, Kere, J, Aaltonen, L A, Arason, A, Møller, P, Kruse, T A, Borg, Å, Winqvist, R

“…Background: BARD1 was originally identified as a BRCA1-interacting protein but has also been described in tumour-suppressive functions independent of BRCA1…”
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A longitudinal study of the effect of GSTT1 and GSTM1 gene copy number on survival by Christiansen, L., Brasch-Andersen, C., Bathum, L., Kruse, T.A., Christensen, K.

“…Deletions of the glutathione S-transferase superfamily genes GSTT1 and GSTM1 has been associated with oxidative stress related diseases and recently explored…”
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Familial isolated hyperparathyroidism as a variant of multiple endocrine neoplasia type 1 in a large danish pedigree by KASSEM, M, KRUSE, T. A, FUNG KI WONG, LARSSON, C, BIN TEAN TEH

“…We report here our genetic findings of a family in which 14 members were affected with isolated primary hyperparathyroidism. Hyperparathyroidism is the main…”
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Mutations in endoglin and in activin receptor-like kinase 1 among Danish patients with hereditary haemorrhagic telangiectasia by Brusgaard, K, Kjeldsen, AD, Poulsen, L, Moss, H, Vase, P, Rasmussen, K, Kruse, TA, Hørder, M

“…Hereditary haemorrhagic telangiectasia (HHT) is a rare disorder with one per 6000–10,000 affected individuals in the general Caucasian population. HHT is…”
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Asset Liquidity and the Determinants of Asset Sales by Poorly Performing Firms by Kruse, Timothy A.

“…This study analyzes factors that potentially are associated with higher incidences of asset sales by poorly performing firms. Consistent with Shleifer and…”
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