Search Results - "Kruse, Sebastian"

A trypanosome-derived immunotherapeutics platform elicits potent high-affinity antibodies, negating the effects of the synthetic opioid fentanyl by Triller, Gianna, Vlachou, Evi P., Hashemi, Hamidreza, van Straaten, Monique, Zeelen, Johan P., Kelemen, Yosip, Baehr, Carly, Marker, Cheryl L., Ruf, Sandra, Svirina, Anna, Chandra, Monica, Urban, Katharina, Gkeka, Anastasia, Kruse, Sebastian, Baumann, Andreas, Miller, Aubry K., Bartel, Marc, Pravetoni, Marco, Stebbins, C. Erec, Papavasiliou, F. Nina, Verdi, Joseph P.

“…Poorly immunogenic small molecules pose challenges for the production of clinically efficacious vaccines and antibodies. To address this, we generate an…”
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Therapeutic vaccination using minimal HPV16 epitopes in a novel MHC-humanized murine HPV tumor model by Kruse, Sebastian, Büchler, Marleen, Uhl, Philipp, Sauter, Max, Scherer, Philipp, Lan, Tammy C.T., Zottnick, Samantha, Klevenz, Alexandra, Yang, Ruwen, Rösl, Frank, Mier, Walter, Riemer, Angelika B.

“…Therapeutic vaccination as a treatment option for HPV-induced cancers is actively pursued because the two HPV proteins E6 and E7 represent ideal targets for…”
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Development of an Orthotopic HPV16-Dependent Base of Tongue Tumor Model in MHC-Humanized Mice by Schifflers, Christoph, Zottnick, Samantha, Förster, Jonas D, Kruse, Sebastian, Yang, Ruwen, Wiethoff, Hendrik, Bozza, Matthias, Hoppe-Seyler, Karin, Heikenwälder, Mathias, Harbottle, Richard P, Michiels, Carine, Riemer, Angelika B

“…Head and neck squamous cell carcinomas (HNSCC) caused by infections with high-risk human papillomaviruses (HPV) are responsible for an increasing number of…”
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How Does CEO Decision Style Influence Firm Performance? The Mediating Role of Speed and Innovativeness in New Product Development by Kruse, Sebastian, Bendig, David, Brettel, Malte

“…Although chief executive officers (CEOs) are the primary decision‐makers in their firms, there has been little research on how CEOs' decision styles affect…”
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The Potency of Shortcuts in Decision-Making by Kruse, Sebastian, Bendig, David, Brettel, Malte

“…Chief executive officers (CEOs) who use heuristics, or shortcuts, in decision-making can make more effective choices than those who rely on comprehensive…”
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Achieving Product Ambidexterity in New Product Development: The Role of Middle Managers' Dynamic Managerial Capabilities by Greven, Andrea, Kruse, Sebastian, Vos, Anne, Strese, Steffen, Brettel, Malte

“…While the concept of dynamic managerial capabilities was initially developed to understand top managers' strategic decisions, we theorize that it can explain…”
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The influence of joints on friction induced vibration in brake squeal by Kruse, Sebastian, Tiedemann, Merten, Zeumer, Bernhard, Reuss, Pascal, Hetzler, Hartmut, Hoffmann, Norbert

“…The effect of joints on flutter type friction induced oscillation in friction brakes is investigated. The work is based on a small characteristic system with…”
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Establishment of closed 35S ribosomal RNA gene chromatin in stationary Saccharomyces cerevisiae cells by Babl, Virginia, Girke, Philipp, Kruse, Sebastian, Pinz, Sophia, Hannig, Katharina, Schächner, Christopher, Hergert, Kristin, Wittner, Manuel, Seufert, Wolfgang, Milkereit, Philipp, Tschochner, Herbert, Griesenbeck, Joachim

“…As a first step in eukaryotic ribosome biogenesis RNA polymerase (Pol) I synthesizes a large ribosomal RNA (rRNA) precursor from multicopy rRNA gene loci. This…”
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Certolizumab pegol treatment in axial spondyloarthritis mitigates fat lesion development: 4-year post-hoc MRI results from a phase 3 study by Baraliakos, Xenofon, Kruse, Sebastian, Auteri, Simone E, de Peyrecave, Natasha, Nurminen, Tommi , Kumke, Thomas, Hoepken, Bengt, Braun, Jürgen

“…Abstract Objectives Fat lesions (FLs) on MRI T1 sequences are considered to be early indicators of structural spinal progression in axial spondyloarthritis…”
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Establishment and Maintenance of Open Ribosomal RNA Gene Chromatin States in Eukaryotes by Schächner, Christopher, Merkl, Philipp E, Pilsl, Michael, Schwank, Katrin, Hergert, Kristin, Kruse, Sebastian, Milkereit, Philipp, Tschochner, Herbert, Griesenbeck, Joachim

“…In growing eukaryotic cells, nuclear ribosomal (r)RNA synthesis by RNA polymerase (RNAP) I accounts for the vast majority of cellular transcription. This high…”
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RHEEMix in the data jungle: a cost-based optimizer for cross-platform systems by Kruse, Sebastian, Kaoudi, Zoi, Contreras-Rojas, Bertty, Chawla, Sanjay, Naumann, Felix, Quiané-Ruiz, Jorge-Arnulfo

“…Data analytics are moving beyond the limits of a single platform. In this paper, we present the cost-based optimizer of Rheem, an open-source cross-platform…”
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Abstract 721: Development of a therapeutic HPV vaccine based on mass spectrometry-verified target epitopes by Kruse, Sebastian, Bonsack, Maria, Becker, Sara, Mohan, Nitya, Steinbach, Alina, Hoppe, Stephanie, Blatnik, Renata, Riemer, Angelika B.

“…Abstract For rational therapeutic vaccine design, detailed knowledge about target epitopes that are truly presented on cancer cells is essential. Many…”
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Erratum to “The influence of joints on friction induced vibration in brake squeal” [J. Sound Vib. 340 (2014) 239–252] by Kruse, Sebastian, Tiedemann, Merten, Zeumer, Bernhard, Reuss, Pascal, Hetzler, Hartmut, Hoffmann, Norbert

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Optimizing Cross-Platform Data Movement by Kruse, Sebastian, Kaoudi, Zoi, Quiane-Ruiz, Jorge-Arnulfo, Chawla, Sanjay, Naumann, Felix, Contreras-Rojas, Bertty

“…Data analytics are moving beyond the limits of a single data processing platform. A cross-platform query optimizer is necessary to enable applications to run…”
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Accuracy of 64-multidetector computed tomography coronary angiography in patients with symptomatic atrial fibrillation prior to pulmonary vein isolation by Sohns, Christian, Kruse, Sebastian, Vollmann, Dirk, Lüthje, Lars, Dorenkamp, Marc, Seegers, Joachim, Jacobshagen, Claudius, Leber, Alexander W, Obenauer, Silvia, Hasenfuss, Gerd, Zabel, Markus

“…Aim of our study was to investigate the value of multidetector computed tomography (MDCT) for detecting significant stenoses of coronary arteries in patients…”
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Phosphorylation of human cardiac troponin I G203S and K206Q linked to familial hypertrophic cardiomyopathy affects actomyosin interaction in different ways by Deng, Yi, Schmidtmann, Anja, Kruse, Sebastian, Filatov, Vladimir, Heilmeyer, Ludwig M.G., Jaquet, Kornelia, Thieleczek, Rolf

“…cAMP-dependent protein kinase (PKA)-dependent phosphorylation of the two serine residues in the amino terminal region unique to cardiac troponin I (cTnI) is…”
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RHEEMix in the Data Jungle: A Cost-based Optimizer for Cross-platform Systems by Kruse, Sebastian, Kaoudi, Zoi, Contreras, Bertty, Chawla, Sanjay, Naumann, Felix, Quiané-Ruiz, Jorge-Arnulfo

“…VLDB Journal 2020 In pursuit of efficient and scalable data analytics, the insight that "one size does not fit all" has given rise to a plethora of specialized…”
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Building your Cross-Platform Application with RHEEM by Chawla, Sanjay, Contreras-Rojas, Bertty, Kaoudi, Zoi, Kruse, Sebastian, Quiané-Ruiz, Jorge-Arnulfo

“…Today, organizations typically perform tedious and costly tasks to juggle their code and data across different data processing platforms. Addressing this pain…”
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Designing Automated Allocation Mechanisms for Service Procurement of Imperfectly Substitutable Services by Kruse, S., Brintrup, A., McFarlane, D., Sanchez Lopez, Tomás, Owens, K., Krechel, W. E.

“…Self-serving assets (SSAs) are a new interpretation of the intelligent product technology, set to transform product lifecycle management through automation…”
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Reviews by Lehmann, Ina, Westermann, Nina, Kruse, Sebastian, Moody, Stanley, Jindrová, Marcela

“…Haizam Amirah Fernández and Richard Youngs (eds.): The Euro-Mediterranean Partnership: Assessing the First Decade. Madrid: Real Instituto Elcano, FRIDE, 2005,…”
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