Search Results - "Kruse, Jan"

Polyoxometalate‐Soft Matter Composite Materials: Design Strategies, Applications, and Future Directions by Kruse, Jan‐Hendrik, Langer, Marcel, Romanenko, Iuliia, Trentin, Ivan, Hernández‐Castillo, David, González, Leticia, Schacher, Felix H., Streb, Carsten

“…Molecular metal oxides or polyoxometalates (POMs) offer unrivaled properties in areas ranging from catalysis and energy conversion through to molecular…”
Get full text

Modes of p53 Regulation by Kruse, Jan-Philipp, Gu, Wei

“…The traditional view of p53 activation includes three steps—p53 stabilization, DNA binding, and transcriptional activation. However, recent studies indicate…”
Get full text

Simplified lung ultrasound protocol shows excellent prediction of extravascular lung water in ventilated intensive care patients by Enghard, Philipp, Rademacher, Sibylle, Nee, Jens, Hasper, Dietrich, Engert, Ulrike, Jörres, Achim, Kruse, Jan M

“…Ultrasound of the lung and quantification of B lines was recently introduced as a novel tool to detect overhydration. In the present study, we aimed to…”
Get full text

Multimodal Analysis of Light‐Driven Water Oxidation in Nanoporous Block Copolymer Membranes by Kund, Julian, Kruse, Jan‐Hendrik, Gruber, Andreas, Trentin, Ivan, Langer, Marcel, Read, Clarissa, Neusser, Gregor, Blaimer, Dominik, Rupp, Ulrich, Streb, Carsten, Leopold, Kerstin, Schacher, Felix H., Kranz, Christine

“…Heterogeneous light‐driven catalysis is a cornerstone of sustainable energy conversion. Most catalytic studies focus on bulk analyses of the hydrogen and…”
Get full text

Different Routes to Ampholytic Polydehydroalanine: Orthogonal versus Simultaneous Deprotection by Kruse, Jan‐Hendrik, Biehl, Philip, Schacher, Felix Helmut

“…Polydehydroalanine (PDha) is a polyampholyte featuring both a –NH2 and a –COOH in every repeat unit and with that presents a rather high charge density. The…”
Get full text

SnapShot: p53 Posttranslational Modifications by Kruse, Jan-Philipp, Gu, Wei

Get full text

A Molecular Photosensitizer in a Porous Block Copolymer Matrix‐Implications for the Design of Photocatalytically Active Membranes by Chettri, Avinash, Kruse, Jan‐Hendrik, Kumar Jha, Keshav, Dröge, Lara, Romanenko, Iuliia, Neumann, Christof, Kupfer, Stephan, Turchanin, Andrey, Rau, Sven, Schacher, Felix H., Dietzek, Benjamin

“…Recently, porous photocatalytically active block copolymer membranes were introduced, based on heterogenized molecular catalysts. Here, we report the…”
Get full text

Negative regulation of the deacetylase SIRT1 by DBC1 by Qin, Jun, Kruse, Jan-Philipp, Gu, Wei, Tang, Yi, Zhao, Wenhui, Jung, Sung Yun

“…SIRT1 is an NAD-dependent deacetylase critically involved in stress responses, cellular metabolism and, possibly, ageing. The tumour suppressor p53 represents…”
Get full text

Future unmet medical need as a guiding principle for pharmaceutical R&D by Vennemann, Matthias, Ruland, Vincent, Kruse, Jan-Philip, Harloff, Christine, Trübel, Hubert, Gielen-Haertwig, Heike

“…•Novel methodology to systematically assess unmet medical need.•Unmet medical need is determined by the expected future standard of care.•Future unmet medical…”
Get full text

How Can Science and Research Work Well? Toward a Critique of New Public Management Practices in Academia From a Socio-Philosophical Perspective by Kruse, Jan-Philipp

“…While practices (NPM) have been adopted in academia and higher education over the past two decades, this paper is investigating their role in a specifically…”
Get full text

Association of hyperfibrinolysis with poor prognosis in refractory circulatory arrest: implications for extracorporeal cardiopulmonary resuscitation by Magomedov, Abakar, Kruse, Jan M, Zickler, Daniel, Kunz, Julius V, Koerner, Roland, Piper, Sophie K, Kamhieh-Milz, Julian, Eckardt, Kai-Uwe, Nee, Jens

“…Identifying candidates for extracorporeal cardiopulmonary resuscitation (eCPR) is challenging, and novel predictive markers are urgently needed…”
Get more information

Stage, treatment and survival of low‐grade serous ovarian carcinoma in the Netherlands: A nationwide study by De Decker, Koen, Wenzel, Hans H. B., Bart, Joost, Aa, Maaike A., Kruitwagen, Roy F. P. M., Nijman, Hans W., Kruse, Arnold‐Jan

“…Introduction Serous ovarian carcinomas constitute the largest group of epithelial ovarian cancer (60%–75%) and are further classified into high‐ and low‐grade…”
Get full text

Maxi-Min Language Use A Critical Remark on a Concept by Philippe van Parijs by Kruse, Jan

“…Philippe van Parijs explains in the concept of maxi-min language use as a process of language choice. He suggests that the language chosen as a common language…”
Get full text

SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity by Steiner, Sophie, Schwarz, Tatjana, Corman, Victor M, Gebert, Laura, Kleinschmidt, Malte C, Wald, Alexandra, Gläser, Sven, Kruse, Jan M, Zickler, Daniel, Peric, Alexander, Meisel, Christian, Meyer, Tim, Staudacher, Olga L, Wittke, Kirsten, Kedor, Claudia, Bauer, Sandra, Besher, Nabeel Al, Kalus, Ulrich, Pruß, Axel, Drosten, Christian, Volk, Hans-Dieter, Scheibenbogen, Carmen, Hanitsch, Leif G

“…Morbidity and mortality of COVID-19 is increased in patients with inborn errors of immunity (IEI). Age and comorbidities and also impaired type I interferon…”
Get full text

FoxO1 protects against pancreatic β cell failure through NeuroD and MafA induction by Kitamura, Yukari Ido, Kitamura, Tadahiro, Kruse, Jan-Philipp, Raum, Jeffrey C., Stein, Roland, Gu, Wei, Accili, Domenico

“…Diabetes causes pancreatic β cell failure through hyperglycemia-induced oxidative stress, or “glucose toxicity.” We show that the forkhead protein FoxO1…”
Get full text

Topical imiquimod treatment of residual or recurrent cervical intraepithelial neoplasia lesions (TOPIC-2): A randomised controlled trial by van de Sande, Anna J M, van Baars, Romy, Koeneman, Margot M, Gerestein, Cornelis G, Kruse, Arnold-Jan, van Esch, Edith M G, de Vos van Steenwijk, Peggy J, Muntinga, Caroline L P, Willemsen, Sten P, van Doorn, Helena C, van Kemenade, Folkert J, van Beekhuizen, Helene J

“…To investigate the efficacy of imiquimod in women with residual or recurrent cervical intraepithelial neoplasia (rrCIN), compared with large loop excision of…”
Get full text

COVID19-associated cardiomyocyte dysfunction, arrhythmias and the effect of Canakinumab by Dimai, Sanzio, Semmler, Lukas, Prabhu, Ashok, Stachelscheid, Harald, Huettemeister, Judith, Klaucke, Sandra C, Lacour, Philipp, Blaschke, Florian, Kruse, Jan, Parwani, Abdul, Boldt, Leif-Hendrik, Bullinger, Lars, Pieske, Burkert M, Heinzel, Frank R, Hohendanner, Felix

“…Background Cardiac injury associated with cytokine release frequently occurs in SARS-CoV-2 mediated coronavirus disease (COVID19) and mortality is particularly…”
Get full text

Efficacy and complications of regional citrate anticoagulation during continuous renal replacement therapy in critically ill patients with COVID-19 by Khadzhynov, Dmytro, von dem Berge, Uwe, Muench, Frédéric, Karaivanov, Stoyan, Koerner, Roland, Kruse, Jan M., Zickler, Daniel, Budde, Klemens, Eckardt, Kai-Uwe, Lehner, Lukas J.

“…We compared filter survival and citrate-induced complications during continuous renal replacement therapy (CRRT) with regional citrate anticoagulation (RCA) in…”
Get full text

Establishment of an extracorporeal cardio-pulmonary resuscitation program in Berlin - outcomes of 254 patients with refractory circulatory arrest by Nee, Jens, Koerner, Roland, Zickler, Daniel, Schroeder, Tim, Enghard, Philipp, Nibbe, Lutz, Hasper, Dietrich, Buder, Robert, Leithner, Christoph, Ploner, Christoph J, Eckardt, Kai-Uwe, Storm, Christian, Kruse, Jan M

“…Optimal management of out of hospital circulatory arrest (OHCA) remains challenging, in particular in patients who do not develop rapid return of spontaneous…”
Get full text

Thromboembolic complications in critically ill COVID-19 patients are associated with impaired fibrinolysis by Kruse, Jan Matthias, Magomedov, Abakar, Kurreck, Annika, Münch, Frédéric H, Koerner, Roland, Kamhieh-Milz, Julian, Kahl, Andreas, Gotthardt, Inka, Piper, Sophie K, Eckardt, Kai-Uwe, Dörner, Thomas, Zickler, Daniel

“…There is emerging evidence for enhanced blood coagulation in coronavirus 2019 (COVID-19) patients, with thromboembolic complications contributing to morbidity…”
Get full text