Search Results - "Krungkrai, SR"

The antimalarial action on Plasmodium falciparum of qinghaosu and artesunate in combination with agents which modulate oxidant stress by Krungkrai, S R, Yuthavong, Y

“…The antimalarial activity of qinghaosu (artemisinine) against Plasmodium falciparum in culture was enhanced by increased oxygen tension. Artesunate, a…”
Get more information

Malaria parasite carbonic anhydrase:inhibition of aromatic/heterocyclic sulfonamides and its therapeutic potential by Krungkrai, Sudaratana R, Krungkrai, Jerapan

“…Plasmodium falciparum（P.falciparum） is responsible for the majority of life-threatening cases of human malaria,causing 1.5-2.7 million annual deaths.The global…”
Get full text

Dihydroorotase of human malarial parasite Plasmodium falciparum differs from host enzyme by Krungkrai, Sudaratana R., Wutipraditkul, Nuchanat, Krungkrai, Jerapan

“…Plasmodium falciparum, the causative agent of human malaria, is totally dependent on de novo pyrimidine biosynthetic pathway. A gene encoding P. falciparum…”
Get full text

A Novel Enzyme Complex of Orotate Phosphoribosyltransferase and Orotidine 5‘-Monophosphate Decarboxylase in Human Malaria Parasite Plasmodium falciparum:  Physical Association, Kinetics, and Inhibition Characterization by Krungkrai, Sudaratana R, DelFraino, Brian J, Smiley, Jeffrey A, Prapunwattana, Phisit, Mitamura, Toshihide, Horii, Toshihiro, Krungkrai, Jerapan

“…Human malaria parasite, Plasmodium falciparum, can only synthesize pyrimidine nucleotides using the de novo pathway, whereas mammalian cells obtain pyrimidine…”
Get full text

Characterisation of carbonic anhydrase in Plasmodium falciparum by Krungkrai, Sudaratana R, Suraveratum, Nongluk, Rochanakij, Sunant, Krungkrai, Jerapan

“…Here we report the existence, purification and characterisation of carbonic anhydrase in Plasmodium falciparum. The infected red cells contained carbonic…”
Get full text

Orotate phosphoribosyltransferase and orotidine 5 super()-monophosphate decarboxylase exist as multienzyme complex in human malaria parasite Plasmodium falciparum by Krungkrai, SR, Prapunwattana, P, Horii, T, Krungkrai, J

“…Plasmodium falciparum, the causative agent of the most lethal form of human malaria, totally depends on de novo pyrimidine biosynthetic pathway. Orotate…”
Get full text

Human malaria parasite orotate phosphoribosyltransferase: functional expression, characterization of kinetic reaction mechanism and inhibition profile by Krungkrai, Sudaratana R, Aoki, Sayaka, Palacpac, Nirianne Marie Q, Sato, Dan, Mitamura, Toshihide, Krungkrai, Jerapan, Horii, Toshihiro

“…Plasmodium falciparum, the causative agent of the most lethal form of human malaria, relies on de novo pyrimidine biosynthesis. A gene encoding orotate…”
Get full text

Mitochondrial NADH Dehydrogenase from Plasmodium falciparum and Plasmodium berghei by Krungkrai, Jerapan, Kanchanarithisak, Rachanok, Krungkrai, Sudaratana R., Rochanakij, Sunant

“…Krungkrai, J., Kanchanarithisak, R., Krungkrai, S. R. and Rochanakij, S. 2001. Mitochondrial NADH dehydrogenase from Plasmodium falciparum and Plasmodium…”
Get full text

Purification and characterization of Plasmodium falciparum succinate dehydrogenase by Suraveratum, Nongluk, Krungkrai, Sudaratana R, Leangaramgul, Preecha, Prapunwattana, Phisit, Krungkrai, Jerapan

“…Succinate dehydrogenase (SDH), a Krebs cycle enzyme and complex II of the mitochondrial electron transport system,was purified to near homogeneity from the…”
Get full text

Ultrastructure and function of mitochondria in gametocytic stage of Plasmodium falciparum by Krungkrai, J, Prapunwattana, P, Krungkrai, S R

“…Morphological properties of the mitochondrial organelles in the asexual and sexual gametocytic stages of Plasmodium falciparum have been analyzed and found to…”
Get full text

Antimalarial activity of orotate analogs that inhibit dihydroorotase and dihydroorotate dehydrogenase by Krungkrai, J, Krungkrai, S R, Phakanont, K

“…Dihydroorotase and dihydroorotate dehydrogenase, two enzymes of the pyrimidine biosynthetic pathway, were purified from Plasmodium berghei to apparent…”
Get more information

Mitochondrial ubiquinol-cytochrome C reductase a chemotherapeutic target in human malarial parasite by Krungkrai, J, Krungkrai, SR, Suraveratum, N, Prapunwattana, P

Get full text

Plasmodium berghei: partial purification and characterization of the mitochondrial cytochrome c oxidase by Krungkrai, J, Krungkrai, S R, Bhumiratana, A

“…Mitochondria from a rodent malarial parasite (Plasmodium berghei) were successfully purified by differential centrifugation and 22% Percoll density gradient…”
Get more information