Search Results - "Krumb, Matthias"

A practical and sustainable two-component Minisci alkylation via photo-induced EDA-complex activation by Sharique, Mohammed, Majhi, Jadab, Dhungana, Roshan K, Kammer, Lisa Marie, Krumb, Matthias, Lipp, Alexander, Romero, Eugénie, Molander, Gary A

“…An operationally simple, open-air, and efficient light-mediated Minisci C-H alkylation method is described, based on the formation of an electron…”
Get full text

Multivalency Beats Complexity: A Study on the Cell Uptake of Carbohydrate Functionalized Nanocarriers to Dendritic Cells by Krumb, Matthias, Frey, Marie-Luise, Langhanki, Jens, Forster, Robert, Kowalczyk, Danuta, Mailänder, Volker, Landfester, Katharina, Opatz, Till

“…Herein, we report the synthesis of carbohydrate and glycodendron structures for dendritic cell targeting, which were subsequently bound to hydroxyethyl starch…”
Get full text

Visible Light Enables Aerobic Iodine Catalyzed Glycosylation by Krumb, Matthias, Lucas, Tobias, Opatz, Till

“…A versatile protocol for light induced catalytic activation of thioglycosides using iodine as an inexpensive and readily available photocatalyst was developed…”
Get full text

Front Cover: Visible Light Enables Aerobic Iodine Catalyzed Glycosylation (Eur. J. Org. Chem. 28/2019) by Krumb, Matthias, Lucas, Tobias, Opatz, Till

“…The Front Cover shows the skyline of Mainz illuminated by a sunset. Above the skyline, iodine, illustrated as a flying hero masked with an oxygen bandage,…”
Get full text

HPMA‐Based Nanocarriers for Effective Immune System Stimulation by Kramer, Stefan, Langhanki, Jens, Krumb, Matthias, Opatz, Till, Bros, Matthias, Zentel, Rudolf

“…The selective activation of the immune system using nanoparticles as a drug delivery system is a promising field in cancer therapy. Block copolymers from HPMA…”
Get full text

One-Pot Synthesis of Cereblon Proteolysis Targeting Chimeras via Photoinduced C(sp2)–C(sp3) Cross Coupling and Amide Formation for Proteolysis Targeting Chimera Library Synthesis by Arndt, Christine M., Bitai, Jacqueline, Brunner, Jessica, Opatz, Till, Martinelli, Paola, Gollner, Andreas, Sokol, Kevin R., Krumb, Matthias

“…In this study, a one-pot synthesis via photoinduced C­(sp2)–C­(sp3) coupling followed by amide formation to access proteolysis targeting chimeras (PROTACs) was…”
Get full text

Photoredox-Catalyzed Four-Component Reaction for the Synthesis of Complex Secondary Amines by Kammer, Lisa Marie, Krumb, Matthias, Spitzbarth, Benjamin, Lipp, Benjamin, Kühlborn, Jonas, Busold, Jonas, Mulina, Olga M, Terentev, Alexander O, Opatz, Till

“…The one-pot sulfonylation/aminoalkylation of styrene derivatives furnishing substituted γ-sulfonylamines was accomplished through a photoredox-catalyzed…”
Get full text

Photoredox-mediated hydroalkylation and hydroarylation of functionalized olefins for DNA-encoded library synthesis by Badir, Shorouk O, Lipp, Alexander, Krumb, Matthias, Cabrera-Afonso, María Jesús, Kammer, Lisa Marie, Wu, Victoria E, Huang, Minxue, Csakai, Adam, Marcaurelle, Lisa A, Molander, Gary A

“…DNA-encoded library (DEL) technology features a time- and cost-effective interrogation format for the discovery of therapeutic candidates in the pharmaceutical…”
Get full text

Sesquiterpene Lactones from Vernonia tufnelliae: Structural Characterization and Biological Evaluation by Bitchagno, Gabin Thierry M., Schüffler, Anja, Gross, Jonathan, Krumb, Matthias, Tane, Pierre, Opatz, Till

“…The genus Vernonia is an extremely rich source of biologically active sesquiterpene lactones. The present report describes the spectroscopic structure…”
Get full text

Total Synthesis of a Partial Structure from Arabinogalactan and Its Application for Allergy Prevention by Krumb, Matthias, Jäger, Maximilian, Voss, Alice, Immig, Loreen, Peters, Karin, Kowalczyk, Danuta, Bufe, Albrecht, Opatz, Till, Holst, Otto, Vogel, Christian, Peters, Marcus

“…Arabinogalactan, a microheterogeneous polysaccharide occurring in plants, is known for its allergy‐protective activity, which could potentially be used for…”
Get full text

Photochemical C-H arylation of heteroarenes for DNA-encoded library synthesis by Krumb, Matthias, Kammer, Lisa Marie, Badir, Shorouk O, Cabrera-Afonso, María Jesús, Wu, Victoria E, Huang, Minxue, Csakai, Adam, Marcaurelle, Lisa A, Molander, Gary A

“…DNA-encoded library (DEL) technology has emerged as a time- and cost-efficient technique for the identification of therapeutic candidates in the pharmaceutical…”
Get full text

Cover Feature: Total Synthesis of a Partial Structure from Arabinogalactan and Its Application for Allergy Prevention (Chem. Eur. J. 3/2021) by Krumb, Matthias, Jäger, Maximilian, Voss, Alice, Immig, Loreen, Peters, Karin, Kowalczyk, Danuta, Bufe, Albrecht, Opatz, Till, Holst, Otto, Vogel, Christian, Peters, Marcus

“…Growing up in an alpine farming environment with frequent contact to cowsheds is protective against allergic diseases. Arabinogalactan from this environment is…”
Get full text

Neo-clerodane diterpenoids from Conyza pyrrhopappa Sch.Bip. ex A.Rich by Bitchagno, Gabin Thierry M., Schüffler, Anja, Simo, Ingrid K., Krumb, Matthias, Tane, Pierre, Opatz, Till

“…Two hitherto unknown neo-clerodane-type diterpenoids along with twelve known compounds have been isolated from Conyza pyrrhopappa Sch.Bip. ex A.Rich, a…”
Get full text

Visible‐Light‐Induced Cleavage of C−S Bonds in Thioacetals and Thioketals with Iodine as a Photocatalyst by Krumb, Matthias, Kammer, Lisa Marie, Forster, Robert, Grundke, Caroline, Opatz, Till

“…A protocol for a visible‐light‐induced cleavage of thioacetals and thioketals using molecular iodine as a photocatalyst in combination with oxygen as the…”
Get full text

Targeting of Immune Cells with Trimannosylated Liposomes by Wagener, Karolin, Bros, Matthias, Krumb, Matthias, Langhanki, Jens, Pektor, Stefanie, Worm, Matthias, Schinnerer, Meike, Montermann, Evelyn, Miederer, Matthias, Frey, Holger, Opatz, Till, Rösch, Frank

“…Dendritic cells (DCs) are a compelling target in cancer immunotherapy as they initialize strong antigen‐specific immune responses. Drug delivery systems (DDSs)…”
Get full text

Visible‐Light‐Induced Cleavage of C−S Bonds in Thioacetals and Thioketals with Iodine as a Photocatalyst by Krumb, Matthias, Kammer, Lisa Marie, Forster, Robert, Grundke, Caroline, Opatz, Till

“…The front cover artwork is provided by Matthias Krumb and Sarah Susanne Part. It symbolizes the conversion of a dithiane to a ketone through joint activation…”
Get full text

Front Cover: Visible‐Light‐Induced Cleavage of C−S Bonds in Thioacetals and Thioketals with Iodine as a Photocatalyst (ChemPhotoChem 2/2020) by Krumb, Matthias, Kammer, Lisa Marie, Forster, Robert, Grundke, Caroline, Opatz, Till

“…The Cover Feature demonstrates the power of a combination of iodine, oxygen and light to crack C–S bonds, illustrated by two fists smashing a 1,3‐dithiane…”
Get full text

Bioconjugation of Small Molecules to RNA Impedes Its Recognition by Toll-Like Receptor 7 by Hellmuth, Isabell, Freund, Isabel, Schlöder, Janine, Seidu-Larry, Salifu, Thüring, Kathrin, Slama, Kaouthar, Langhanki, Jens, Kaloyanova, Stefka, Eigenbrod, Tatjana, Krumb, Matthias, Röhm, Sandra, Peneva, Kalina, Opatz, Till, Jonuleit, Helmut, Dalpke, Alexander H, Helm, Mark

“…A fundamental mechanism of the innate immune system is the recognition, extra- and intracellular pattern-recognition receptors, of pathogen-associated…”
Get full text

A practical and sustainable two-component Minisci alkylation photo-induced EDA-complex activation by Sharique, Mohammed, Majhi, Jadab, Dhungana, Roshan K, Kammer, Lisa Marie, Krumb, Matthias, Lipp, Alexander, Romero, Eugénie, Molander, Gary A

“…An operationally simple, open-air, and efficient light-mediated Minisci C-H alkylation method is described, based on the formation of an electron…”
Get full text