Search Results - "Krum, Bárbara Nunes"
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Manganese in the Diet: Bioaccessibility, Adequate Intake, and Neurotoxicological Effects
Published in Journal of agricultural and food chemistry (18-11-2020)“…Manganese (Mn) is an essential element that participates in several biological processes. Mn serves as a cofactor for several enzymes, such as glutamine…”
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Ex vivo and in vitro inhibitory potential of Kava extract on monoamine oxidase B activity in mice
Published in Journal of Traditional and Complementary Medicine (01-03-2022)“…Background and aim: This study investigated the effect of Kava extract (Piper methysticum), a medicinal plant that has been worldly used by its anxiolytic…”
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Influence of the dose of ketamine used on schizophrenia-like symptoms in mice: A correlation study with TH, GAD67, and PPAR-γ
Published in Pharmacology, biochemistry and behavior (01-12-2023)“…Schizophrenia is a chronic, debilitating mental illness that has not yet been completely understood. In this study, we aimed to investigate the effects of…”
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In vitro and in vivo evaluation of enzymatic and antioxidant activity, cytotoxicity and genotoxicity of curcumin-loaded solid dispersions
Published in Food and chemical toxicology (01-03-2019)“…Curcumin, the main bioactive polyphenolic compound in Curcuma longa L. rhizomes has a wide range of bioactive properties. Curcumin presents low solubility in…”
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Kava decreases the stereotyped behavior induced by amphetamine in mice
Published in Journal of ethnopharmacology (30-01-2021)“…Kava extract (Piper methysticum) is a phytotherapic mainly used for the treatment of anxiety. Although the reported effects of Kava drinking improving…”
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Behavioral and neurochemical effects induced by reserpine in mice
Published in Psychopharmacology (01-02-2016)“…Rationale Reserpine, a monoamine-depleting agent, which irreversibly and non-selectively blocks the vesicular monoamine transporter, has been used as an animal…”
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Effects of CATECHIN on reserpine-induced vacuous chewing movements: behavioral and biochemical analysis
Published in Naunyn-Schmiedeberg's archives of pharmacology (01-12-2020)“…This study evaluated the effect of (+)-catechin, a polyphenolic compound, on orofacial dyskinesia (OD) induced by reserpine in mice. The potential modulation…”
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Silymarin recovers 6-hydroxydopamine-induced motor deficits in mice
Published in Food and chemical toxicology (01-08-2018)“…•Silymarin recovered 6-OHDA-induced motor impairment.•6-OHDA caused an increase in phospho-ERK1/2 levels.•Silymarin did not modify the alterations in TH and…”
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Harpagophytum Procumbens Ethyl Acetate Fraction Reduces Fluphenazine-Induced Vacuous Chewing Movements and Oxidative Stress in Rat Brain
Published in Neurochemical research (01-05-2016)“…Long-term treatment with fluphenazine is associated with manifestation of extrapyramidal side effects, such as tardive dyskinesia. The molecular mechanisms…”
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10
Influence of the dose of ketamine used on schizophrenia-like symptoms in mice: A correlation study with TH, GAD 67 , and PPAR-γ
Published in Pharmacology, biochemistry and behavior (01-12-2023)“…Schizophrenia is a chronic, debilitating mental illness that has not yet been completely understood. In this study, we aimed to investigate the effects of…”
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11
Haloperidol Interactions with the dop-3 Receptor in Caenorhabditis elegans
Published in Molecular neurobiology (2021)“…Haloperidol is a typical antipsychotic drug commonly used to treat a broad range of psychiatric disorders related to dysregulations in the neurotransmitter…”
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Silymarin has antioxidant potential and changes the activity of Na+/K+-ATPase and monoamine oxidase in vitro
Published in Industrial crops and products (01-08-2015)“…•Silymarin has antioxidant effects in different models in vitro.•Silymarin increases Na+ /K+-ATPase activity in vitro.•Silymarin inhibits MAO activity with a…”
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