Search Results - "Krull, Kevin R."
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Neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic leukemia treated on contemporary treatment protocols: A systematic review
Published in Neuroscience and biobehavioral reviews (01-06-2015)“…The intensified administration of chemotherapeutic drugs has gradually replaced cranial radiation therapy (CRT) for the treatment of childhood acute…”
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Neurocognitive Outcomes and Interventions in Long-Term Survivors of Childhood Cancer
Published in Journal of clinical oncology (20-07-2018)“…Recent research has demonstrated that survivors of childhood cancer are at risk for a myriad of late effects that affect physical and mental quality of life…”
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3
Reduction in Late Mortality among 5-Year Survivors of Childhood Cancer
Published in The New England journal of medicine (03-03-2016)“…Alterations in treatment intensity and decreased use of radiation therapy have reduced the risk of late treatment-related death in long-term survivors of…”
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Late mortality and chronic health conditions in long-term survivors of early-adolescent and young adult cancers: a retrospective cohort analysis from the Childhood Cancer Survivor Study
Published in The lancet oncology (01-03-2020)“…Treatment outcomes among survivors of cancer diagnosed during adolescence and early young adulthood have not been characterised independently of survivors of…”
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The cumulative burden of surviving childhood cancer: an initial report from the St Jude Lifetime Cohort Study (SJLIFE)
Published in The Lancet (British edition) (09-12-2017)“…Survivors of childhood cancer develop early and severe chronic health conditions (CHCs). A quantitative landscape of morbidity of survivors, however, has not…”
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Clinical Ascertainment of Health Outcomes Among Adults Treated for Childhood Cancer
Published in JAMA : the journal of the American Medical Association (12-06-2013)“…IMPORTANCE Adult survivors of childhood cancer are known to be at risk for treatment-related adverse health outcomes. A large population of survivors has not…”
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Comprehensive Echocardiographic Detection of Treatment-Related Cardiac Dysfunction in Adult Survivors of Childhood Cancer
Published in Journal of the American College of Cardiology (16-06-2015)“…Abstract Background Treatment-related cardiac death is the primary, noncancer cause of mortality in adult survivors of childhood malignancies. Early detection…”
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Improving quality and quantity of life for childhood cancer survivors globally in the twenty-first century
Published in Nature reviews. Clinical oncology (01-10-2023)“…The contributions of cooperative groups to performing large-cohort clinical trials and long-term survivorship studies have facilitated advances in treatment,…”
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Long-Term Neurocognitive Functioning and Social Attainment in Adult Survivors of Pediatric CNS Tumors: Results From the St Jude Lifetime Cohort Study
Published in Journal of clinical oncology (20-04-2016)“…To assess the prevalence and severity of neurocognitive impairment in adult survivors of pediatric CNS tumors and to examine associated treatment exposures…”
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Survivors of childhood cancer in the United States: prevalence and burden of morbidity
Published in Cancer epidemiology, biomarkers & prevention (01-04-2015)“…No studies have estimated the population-level burden of morbidity in individuals diagnosed with cancer as children (ages 0-19 years). We updated prevalence…”
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Physiologic Frailty As a Sign of Accelerated Aging Among Adult Survivors of Childhood Cancer: A Report From the St Jude Lifetime Cohort Study
Published in Journal of clinical oncology (20-12-2013)“…Frailty, a phenotype reported among 9.9% of individuals 65 years old and older (9.6% of women; 5.2% of men), has not been assessed among adult childhood cancer…”
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Neurocognitive Outcomes Decades After Treatment for Childhood Acute Lymphoblastic Leukemia: A Report From the St Jude Lifetime Cohort Study
Published in Journal of clinical oncology (10-12-2013)“…To determine rates, patterns, and predictors of neurocognitive impairment in adults decades after treatment for childhood acute lymphoblastic leukemia (ALL)…”
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Remotely-supervised transcranial direct current stimulation (tDCS) for clinical trials: guidelines for technology and protocols
Published in Frontiers in systems neuroscience (17-03-2015)“…The effect of transcranial direct current stimulation (tDCS) is cumulative. Treatment protocols typically require multiple consecutive sessions spanning weeks…”
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Chemotherapy Pharmacodynamics and Neuroimaging and Neurocognitive Outcomes in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia
Published in Journal of clinical oncology (01-08-2016)“…To examine associations among methotrexate pharmacodynamics, neuroimaging, and neurocognitive outcomes in long-term survivors of childhood acute lymphoblastic…”
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Reduced Morbidity and Mortality in Survivors of Childhood Acute Lymphoblastic Leukemia: A Report From the Childhood Cancer Survivor Study
Published in Journal of clinical oncology (10-10-2020)“…Risk-stratified therapy, which modifies treatment on the basis of clinical and biologic features, has improved 5-year overall survival of childhood acute…”
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Social Outcomes in the Childhood Cancer Survivor Study Cohort
Published in Journal of clinical oncology (10-05-2009)“…Difficulties with negotiating and achieving desired social outcomes in life may be exacerbated by the experience of childhood cancer, including adverse effects…”
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Methotrexate-Induced Neurotoxicity and Leukoencephalopathy in Childhood Acute Lymphoblastic Leukemia
Published in Journal of clinical oncology (20-03-2014)“…Methotrexate (MTX) can cause significant clinical neurotoxicity and asymptomatic leukoencephalopathy. We sought to identify clinical, pharmacokinetic, and…”
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Differential Impact of Symptom Prevalence and Chronic Conditions on Quality of Life in Cancer Survivors and Non-Cancer Individuals: A Population Study
Published in Cancer epidemiology, biomarkers & prevention (01-07-2017)“…To compare associations of symptom prevalence, chronic conditions, and health-related quality of life (HRQOL) between cancer survivors and non-cancer…”
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Chronic Health Conditions and Neurocognitive Function in Aging Survivors of Childhood Cancer: A Report from the Childhood Cancer Survivor Study
Published in JNCI : Journal of the National Cancer Institute (01-04-2018)“…Neurocognitive impairment in survivors of childhood cancer may be associated with direct neurotoxicity, as well as indirect effects of systemic health…”
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Determinants and Consequences of Financial Hardship Among Adult Survivors of Childhood Cancer: A Report From the St. Jude Lifetime Cohort Study
Published in JNCI : Journal of the National Cancer Institute (01-02-2019)“…Financial hardship among survivors of pediatric cancer has been understudied. We investigated determinants and consequences of financial hardship among adult…”
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