Search Results - "Kruithof, B. P. T."
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Preservation of human heart valves for replacement in children with heart valve disease: past, present and future
Published in Cell and tissue banking (01-03-2024)“…Valvular heart disease affects 30% of the new-borns with congenital heart disease. Valve replacement of semilunar valves by mechanical, bioprosthetic or donor…”
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The mechanical environment regulates the extent of aortic valve calcification and thickness: an ex vivo whole mouse heart study
Published in European heart journal (28-10-2024)“…Abstract Background Aortic stenosis (AS) is a narrowing of the aortic valve opening due to calcification and thickening of the leaflets. Calcifications are…”
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Novel ex-vivo calcification model for human aortic valves reveals patient-specific effect of compound
Published in Cardiovascular research (29-05-2024)“…Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – National budget only. Main funding source(s): Dekker grant Background Aortic…”
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4
Introducing a novel ex-vivo calcification model for human aortic valves
Published in European heart journal (09-11-2023)“…Abstract Background Aortic stenosis (AS) is a narrowing of the aortic valve opening due to calcification and thickening of the leaflets. There are currently no…”
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Superimposed tissue formation in human aortic valve disease: differences between stenotic and regurgitant valves
Published in European heart journal (12-10-2021)“…Abstract Introduction The formation of superimposed tissue (SIT), a layer on top of the original valve leaflet, has been described in patients with mitral…”
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Cryopreservation of human adult ventricular tissue for the preparation of viable myocardial slices
Published in Cardiovascular research (29-05-2024)“…Abstract Funding Acknowledgements Type of funding sources: Public grant(s) – EU funding. Main funding source(s): REGeRNA Myocardial slices are ultra-thin…”
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Mutation in PDGFRbeta: a potential new pathogenic variant for acquired mitral valve prolapse
Published in Cardiovascular research (29-05-2024)“…Abstract Funding Acknowledgements None. Background Mitral valve prolapse (MVP) due to myxomatous degeneration is characterized by familial clustering, but few…”
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Modeling cardiac injury using human cardiac slices to test therapeutic approaches for cardiac regeneration and repair
Published in European heart journal (09-11-2023)“…Abstract Background Due to limited regenerative capacity of the adult human heart, myocardial infarction causes irreversible damage by inducing the death of…”
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Mutation in PDGFRbeta: a potential new pathogenic variant for mitral valve prolapse
Published in European heart journal (09-11-2023)“…Abstract Background Mitral valve prolapse (MVP) due to myxomatous degeneration is characterized by familial clustering, but few pathogenic genes have been…”
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