Search Results - "Kruglov, Andrey A"

Nonredundant Function of Soluble LTα₃ Produced by Innate Lymphoid Cells in Intestinal Homeostasis by Kruglov, Andrey A., Grivennikov, Sergei I., Kuprash, Dmitry V., Winsauer, Caroline, Prepens, Sandra, Seleznik, Gitta Maria, Eberl, Gerard, Littman, Dan R., Heikenwalder, Mathias, Tumanov, Alexei V., Nedospasov, Sergei A.

“…Immunoglobulin A (IgA) production at mucosal surfaces contributes to protection against pathogens and controls intestinal microbiota composition. However,…”
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Commensal microbiota influence systemic autoimmune responses by Van Praet, Jens T, Donovan, Erin, Vanassche, Inge, Drennan, Michael B, Windels, Fien, Dendooven, Amélie, Allais, Liesbeth, Cuvelier, Claude A, van de Loo, Fons, Norris, Paula S, Kruglov, Andrey A, Nedospasov, Sergei A, Rabot, Sylvie, Tito, Raul, Raes, Jeroen, Gaboriau-Routhiau, Valerie, Cerf-Bensussan, Nadine, Van de Wiele, Tom, Eberl, Gérard, Ware, Carl F, Elewaut, Dirk

“…Antinuclear antibodies are a hallmark feature of generalized autoimmune diseases, including systemic lupus erythematosus and systemic sclerosis. However, the…”
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Interplay Between Microbiota, Toll-Like Receptors and Cytokines for the Maintenance of Epithelial Barrier Integrity by Semin, Iaroslav, Ninnemann, Justus, Bondareva, Marina, Gimaev, Ilia, Kruglov, Andrey A.

“…The intestinal tract is densely populated by microbiota consisting of various commensal microorganisms that are instrumental for the healthy state of the…”
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Akkermansia muciniphila - friend or foe in colorectal cancer? by Gubernatorova, Ekaterina O, Gorshkova, Ekaterina A, Bondareva, Marina A, Podosokorskaya, Olga A, Sheynova, Anna D, Yakovleva, Anastasia S, Bonch-Osmolovskaya, Elizaveta A, Nedospasov, Sergei A, Kruglov, Andrey A, Drutskaya, Marina S

“…is a gram-negative anaerobic bacterium, which represents a part of the commensal human microbiota. Decline in the abundance of among other microbial species in…”
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VHH-Based Bispecific Antibodies Targeting Cytokine Production by Nosenko, Maxim A, Atretkhany, Kamar-Sulu N, Mokhonov, Vladislav V, Efimov, Grigory A, Kruglov, Andrey A, Tillib, Sergei V, Drutskaya, Marina S, Nedospasov, Sergei A

“…Proinflammatory cytokines, such as TNF, IL-6, and IL-1, play pathogenic roles in multiple diseases and are attractive targets for biologic drugs. Because…”
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Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei, Acinetobacter baumannii, and Pseudomonas aeruginosa by Korneev, Kirill V, Arbatsky, Nikolay P, Molinaro, Antonio, Palmigiano, Angelo, Shaikhutdinova, Rima Z, Shneider, Mikhail M, Pier, Gerald B, Kondakova, Anna N, Sviriaeva, Ekaterina N, Sturiale, Luisa, Garozzo, Domenico, Kruglov, Andrey A, Nedospasov, Sergei A, Drutskaya, Marina S, Knirel, Yuriy A, Kuprash, Dmitry V

“…Toll-like receptor 4 (TLR4) is required for activation of innate immunity upon recognition of lipopolysaccharide (LPS) of Gram-negative bacteria. The ability…”
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LTα, TNF, and ILC3 in Peyer’s Patch Organogenesis by Gogoleva, Violetta S., Kuprash, Dmitry V., Grivennikov, Sergei I., Tumanov, Alexei V., Kruglov, Andrey A., Nedospasov, Sergei A.

“…TNF and LTα are structurally related cytokines of the TNF superfamily. Their genes are located in close proximity to each other and to the Ltb gene within the…”
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Synchronization of Wave Flows of Arterial and Venous Blood with Phases of the Cardiac Cycle in Norm: Part 5 by Kruglov, Alexander G, Utkin, Valery N, Vasilyev, Alexander Yu, Kruglov, Andrey A

“…The muscular-fibrous frame of the heart (MFFH) synchronizes and compensates for the pressor effect of the myocardium between the high/low-energy regions…”
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Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection by Xu, Haifeng C, Huang, Jun, Khairnar, Vishal, Duhan, Vikas, Pandyra, Aleksandra A, Grusdat, Melanie, Shinde, Prashant, McIlwain, David R, Maney, Sathish Kumar, Gommerman, Jennifer, Löhning, Max, Ohashi, Pamela S, Mak, Tak W, Pieper, Kathrin, Sic, Heiko, Speletas, Matthaios, Eibel, Hermann, Ware, Carl F, Tumanov, Alexei V, Kruglov, Andrey A, Nedospasov, Sergei A, Häussinger, Dieter, Recher, Mike, Lang, Karl S, Lang, Philipp A

“…The B cell-activating factor (BAFF) is critical for B cell development and humoral immunity in mice and humans. While the role of BAFF in B cells has been…”
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Hypoacylated LPS from Foodborne Pathogen Campylobacter jejuni Induces Moderate TLR4-Mediated Inflammatory Response in Murine Macrophages by Korneev, Kirill V, Kondakova, Anna N, Sviriaeva, Ekaterina N, Mitkin, Nikita A, Palmigiano, Angelo, Kruglov, Andrey A, Telegin, Georgy B, Drutskaya, Marina S, Sturiale, Luisa, Garozzo, Domenico, Nedospasov, Sergei A, Knirel, Yuriy A, Kuprash, Dmitry V

“…Toll-like receptor 4 (TLR4) initiates immune response against Gram-negative bacteria upon specific recognition of lipid A moiety of lipopolysaccharide (LPS),…”
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Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity by Atretkhany, Kamar-Sulu N., Mufazalov, Ilgiz A., Dunst, Josefine, Kuchmiy, Anna, Gogoleva, Violetta S., Andruszewski, David, Drutskaya, Marina S., Faustman, Denise L., Schwabenland, Marius, Prinz, Marco, Kruglov, Andrey A., Waisman, Ari, Nedospasov, Sergei A.

“…TNF is a multifunctional cytokine involved in autoimmune disease pathogenesis that exerts its effects through two distinct TNF receptors, TNFR1 and TNFR2…”
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Group 3 Innate Lymphoid Cells Program a Distinct Subset of IL-22BP-Producing Dendritic Cells Demarcating Solitary Intestinal Lymphoid Tissues by Guendel, Fabian, Kofoed-Branzk, Michael, Gronke, Konrad, Tizian, Caroline, Witkowski, Mario, Cheng, Hung-Wei, Heinz, Gitta Anne, Heinrich, Frederik, Durek, Pawel, Norris, Paula S., Ware, Carl F., Ruedl, Christiane, Herold, Susanne, Pfeffer, Klaus, Hehlgans, Thomas, Waisman, Ari, Becher, Burkhard, Giannou, Anastasios D., Brachs, Sebastian, Ebert, Karolina, Tanriver, Yakup, Ludewig, Burkhard, Mashreghi, Mir-Farzin, Kruglov, Andrey A., Diefenbach, Andreas

“…Solitary intestinal lymphoid tissues such as cryptopatches (CPs) and isolated lymphoid follicles (ILFs) constitute steady-state activation hubs containing…”
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Antibiotic treatment-induced secondary IgA deficiency enhances susceptibility to Pseudomonas aeruginosa pneumonia by Robak, Oliver H, Heimesaat, Markus M, Kruglov, Andrey A, Prepens, Sandra, Ninnemann, Justus, Gutbier, Birgitt, Reppe, Katrin, Hochrein, Hubertus, Suter, Mark, Kirschning, Carsten J, Marathe, Veena, Buer, Jan, Hornef, Mathias W, Schnare, Markus, Schneider, Pascal, Witzenrath, Martin, Bereswill, Stefan, Steinhoff, Ulrich, Suttorp, Norbert, Sander, Leif E, Chaput, Catherine, Opitz, Bastian

“…Broad-spectrum antibiotics are widely used with patients in intensive care units (ICUs), many of whom develop hospital-acquired infections with Pseudomonas…”
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Pathogenic and protective functions of TNF in neuroinflammation are defined by its expression in T lymphocytes and myeloid cells by Kruglov, Andrey A, Lampropoulou, Vicky, Fillatreau, Simon, Nedospasov, Sergei A

“…TNF displays pathogenic activities in many autoimmune disorders. However, anti-TNF therapy in multiple sclerosis patients failed because of poorly understood…”
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Lymphotoxins from distinct types of lymphoid cells differentially contribute to neuroinflammation by Gogoleva, Violetta S., Drutskaya, Marina S., Vorontsov, Alexander I., Atretkhany, Kamar‐Sulu N., Belogurov, Alexey A., Kruglov, Andrey A., Nedospasov, Sergei A.

“…Lymphotoxin α and lymphotoxin β (LTs), TNF superfamily members, are expressed in either soluble (LTα3) or membrane‐bound (LTα1β2 or LTα2β1) forms. In the…”
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IL22BP Mediates the Antitumor Effects of Lymphotoxin Against Colorectal Tumors in Mice and Humans by Kempski, Jan, Giannou, Anastasios D., Riecken, Kristoffer, Zhao, Lilan, Steglich, Babett, Lücke, Jöran, Garcia-Perez, Laura, Karstens, Karl-Frederick, Wöstemeier, Anna, Nawrocki, Mikolaj, Pelczar, Penelope, Witkowski, Mario, Nilsson, Sven, Konczalla, Leonie, Shiri, Ahmad Mustafa, Kempska, Joanna, Wahib, Ramez, Brockmann, Leonie, Huber, Philipp, Gnirck, Ann-Christin, Turner, Jan-Eric, Zazara, Dimitra E., Arck, Petra C., Stein, Alexander, Simon, Ronald, Daubmann, Anne, Meiners, Jan, Perez, Daniel, Strowig, Till, Koni, Pandelakis, Kruglov, Andrey A., Sauter, Guido, Izbicki, Jakob R., Guse, Andreas H., Rösch, Thomas, Lohse, Ansgar W., Flavell, Richard A., Gagliani, Nicola, Huber, Samuel

“…Unregulated activity of interleukin (IL) 22 promotes intestinal tumorigenesis in mice. IL22 binds the antagonist IL22 subunit alpha 2 (IL22RA2, also called…”
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Inactivated whole virion vaccine protects K18‐hACE2 Tg mice against the Omicron SARS‐CoV‐2 variant via cross‐reactive T cells and nonneutralizing antibody responses by Kruglov, Andrey A., Bondareva, Marina A., Gogoleva, Violetta S., Semin, Iaroslav K., Astrakhantseva, Irina V., Zvartsev, Ruslan, Lunin, Aleksandr S., Apolokhov, Vasiliy D., Shustova, Elena Yu, Volok, Viktor P., Ustyugov, Aleksey A., Ishmukhametov, Aydar A., Nedospasov, Sergei A., Kozlovskaya, Liubov I., Drutskaya, Marina S.

“…COVID‐19 is a systemic inflammatory disease initiated by SARS‐CoV‐2 virus infection. Multiple vaccines against the Wuhan variant of SARS‐CoV‐2 have been…”
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TNF hampers intestinal tissue repair in colitis by restricting IL-22 bioavailability by Ninnemann, Justus, Winsauer, Caroline, Bondareva, Marina, Kühl, Anja A., Lozza, Laura, Durek, Pawel, Lissner, Donata, Siegmund, Britta, Kaufmann, Stefan H. E., Mashreghi, Mir-Farzin, Nedospasov, Sergei A., Kruglov, Andrey A.

“…Successful treatment of chronic inflammatory diseases integrates both the cessation of inflammation and the induction of adequate tissue repair processes…”
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Resonant Actualization of Cultural Codes as a Determinant of Mental and Social Transformations (Part 2) by Kruglov, Alexander, Kruglov, Andrey

“…The cumulation of cultural codes forms and structures the integral matrix of information capacity - the cognitive thesaurus (CT) of the psyche. The…”
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Resonant Actualization of Cultural Codes as a Determinant of Mental and Social Transformations (Part 1) by Kruglov, Alexander, Kruglov, Andrey

“…The unification of cultural codes forms the basic set of code symbols (image+sense), which are the basis for recognition, orientation, social cooperation, and…”
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