Search Results - "Krueger, Stefan R."

Rapid structural alterations of the active zone lead to sustained changes in neurotransmitter release by Matz, Jacob, Gilyan, Andrew, Kolar, Annette, McCarvill, Terrence, Krueger, Stefan R., Stevens, Charles F.

“…The likelihood with which an action potential elicits neurotransmitter release, the release probability (p r ), is an important component of synaptic strength…”
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The polarity protein Angiomotin p130 controls dendritic spine maturation by Wigerius, Michael, Quinn, Dylan, Diab, Antonios, Clattenburg, Leanne, Kolar, Annette, Qi, Jiansong, Krueger, Stefan R, Fawcett, James P

“…The actin cytoskeleton is essential for the structural changes in dendritic spines that lead to the formation of new synapses. Although the molecular…”
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Pan-neurexin perturbation results in compromised synapse stability and a reduction in readily releasable synaptic vesicle pool size by Quinn, Dylan P., Kolar, Annette, Wigerius, Michael, Gomm-Kolisko, Rachel N., Atwi, Hanine, Fawcett, James P., Krueger, Stefan R.

“…Neurexins are a diverse family of cell adhesion molecules that localize to presynaptic specializations of CNS neurons. Heterologous expression of neurexins in…”
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The Stability of Glutamatergic Synapses Is Independent of Activity Level, but Predicted by Synapse Size by Quinn, Dylan P, Kolar, Annette, Harris, Sydney A, Wigerius, Michael, Fawcett, James P, Krueger, Stefan R

“…Neuronal activity is thought to drive the remodeling of circuits in the mammalian cerebral cortex. However, its precise function in the underlying formation…”
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Distribution, subcellular localization and ontogeny of ASIC1 in the mammalian central nervous system by Rosa, Diego Alvarez, Krueger, Stefan R., Kolar, Annette, Shao, Deren, Fitzsimonds, Reiko Maki, Canessa, Cecilia M.

“…The acid-sensitive ion channel ASIC1 is a proton-gated ion channel from the mammalian nervous system. Its expression in sensory neurons and activation by low…”
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The Presynaptic Release Apparatus Is Functional in the Absence of Dendritic Contact and Highly Mobile within Isolated Axons by Krueger, Stefan R., Kolar, Annette, Fitzsimonds, Reiko Maki

“…Whether contact of an axon with a dendrite is a necessary inductive signal for the assembly of functional presynaptic machinery is controversial. Combining…”
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NCK1 Modulates Neuronal Actin Dynamics and Promotes Dendritic Spine, Synapse, and Memory Formation by Diab, Antonios M, Wigerius, Michael, Quinn, Dylan P, Qi, Jiansong, Shahin, Ibrahim, Paffile, Julia, Krueger, Kavita, Karten, Barbara, Krueger, Stefan R, Fawcett, James P

“…Memory formation and maintenance is a dynamic process involving the modulation of the actin cytoskeleton at synapses. Understanding the signaling pathways that…”
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Expression of Neuroserpin, an Inhibitor of Tissue Plasminogen Activator, in the Developing and Adult Nervous System of the Mouse by Krueger, Stefan R, Ghisu, Gian-Piero, Cinelli, Paolo, Gschwend, Thomas P, Osterwalder, Thomas, Wolfer, David P, Sonderegger, Peter

“…Neuroserpin is a serine protease inhibitor of the serpin family that has been identified as an axonally secreted glycoprotein in neuronal cultures of chicken…”
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Pre-synaptic defects of NPC1-deficient hippocampal neurons are not directly related to plasma membrane cholesterol by Hawes, Cory M, Wiemer, Hana, Krueger, Stefan R, Karten, Barbara

“…J. Neurochem. (2010) 114, 311-332. Imbalances in brain cholesterol homeostasis have been observed in several neurodegenerative diseases. In Niemann-Pick Type C…”
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NOS1AP Associates with Scribble and Regulates Dendritic Spine Development by Richier, Lindsay, Williton, Kelly, Clattenburg, Leanne, Colwill, Karen, O'Brien, Michael, Tsang, Christopher, Kolar, Annette, Zinck, Natasha, Metalnikov, Pavel, Trimble, William S, Krueger, Stefan R, Pawson, Tony, Fawcett, James P

“…The formation and function of the neuronal synapse is dependent on the asymmetric distribution of proteins both presynaptically and postsynaptically. Recently,…”
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Neuroprotection by Nicotine in Mouse Primary Cortical Cultures Involves Activation of Calcineurin and L-Type Calcium Channel Inactivation by Stevens, Tanya R, Krueger, Stefan R, Fitzsimonds, Reiko M, Picciotto, Marina R

“…Regulation of intracellular calcium influences neuronal excitability, synaptic plasticity, gene expression, and neurotoxicity. In this study, we investigated…”
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Automated criteria-based selection and analysis of fluorescent synaptic puncta by Bergsman, Jeremy B., Krueger, Stefan R., Fitzsimonds, Reiko Maki

“…The use of fluorescent probes such as FM 1-43 or synapto-pHluorin to study the dynamic aspects of synaptic function has dramatically increased in recent years…”
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Neurotrypsin, a Novel Multidomain Serine Protease Expressed in the Nervous System by Gschwend, Thomas P., Krueger, Stefan R., Kozlov, Serguei V., Wolfer, David P., Sonderegger, Peter

“…We have cloned a novel murine cDNA encoding a multidomain serine protease, termed neurotrypsin, which exhibits an unprecedented domain composition. The deduced…”
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Human Neuroserpin (PI12): cDNA Cloning and Chromosomal Localization to 3q26 by Schrimpf, Sabine P., Bleiker, Andreas J., Brecevic, Lukrecija, Kozlov, Serguei V., Berger, Philipp, Osterwalder, Thomas, Krueger, Stefan R., Schinzel, Albert, Sonderegger, Peter

“…Neuroserpin is a novel serine protease inhibitor of the serpin family. It has been reported as a 55-kDa glycoprotein that is secreted from the axons of…”
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Structure of the mouse gene for the serine protease inhibitor neuroserpin (PI12) by Berger, Philipp, Kozlov, Serguei V., Krueger, Stefan R., Sonderegger, Peter

“…Neuroserpin (PI12), initially identified as an axonally secreted protein in cultured chicken dorsal root ganglion neurons, belongs to the serpin family of the…”
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