Search Results - "Krueger, Peter"
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Immune tolerance of food is mediated by layers of CD4+ T cell dysfunction
Published in Nature (London) (28-07-2022)“…Gastrointestinal health depends on the adaptive immune system tolerating the foreign proteins in food 1 , 2 . This tolerance is paradoxical because the immune…”
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High-affinity memory B cells induced by SARS-CoV-2 infection produce more plasmablasts and atypical memory B cells than those primed by mRNA vaccines
Published in Cell reports (Cambridge) (12-10-2021)“…Although both infections and vaccines induce memory B cell (MBC) populations that participate in secondary immune responses, the MBCs generated in each case…”
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The Constant Region of the Membrane Immunoglobulin Mediates B Cell-Receptor Clustering and Signaling in Response to Membrane Antigens
Published in Immunity (Cambridge, Mass.) (16-01-2009)“…B cells are activated in vivo after the B cell receptors (BCRs) bind to antigens captured on the surfaces of antigen-presenting cells. Antigen binding results…”
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CD4 + Memory T-Cell Formation during Type 1 Immune Responses
Published in Cold Spring Harbor perspectives in biology (01-12-2021)“…Naive CD4 T cells become memory cells after proliferating in response to their cognate major histocompatibility complex class II (MHCII)-bound peptide and…”
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5
Two sequential activation modules control the differentiation of protective T helper-1 (Th1) cells
Published in Immunity (Cambridge, Mass.) (13-04-2021)“…Interferon-γ (IFN-γ)-producing CD4+ T helper-1 (Th1) cells are critical for protection from microbes that infect the phagosomes of myeloid cells. Current…”
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NKp46+ natural killer cells attenuate metabolism‐induced hepatic fibrosis by regulating macrophage activation in mice
Published in Hepatology (Baltimore, Md.) (01-03-2016)“…Nonalcoholic steatohepatitis (NASH) affects 3%‐5% of the U.S. population, having severe clinical complications to the development of fibrosis and end‐stage…”
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MHC class II tetramers engineered for enhanced binding to CD4 improve detection of antigen-specific T cells
Published in Nature biotechnology (01-08-2021)“…The ability to identify T cells that recognize specific peptide antigens bound to major histocompatibility complex (MHC) molecules has enabled enumeration and…”
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FcRL4 acts as an adaptive to innate molecular switch dampening BCR signaling and enhancing TLR signaling
Published in Blood (08-12-2011)“…Fc receptor–like 4 (FcRL4) is expressed on the surface of a subset of memory B cells (MBCs) located at sites of invading pathogens in mucosal lymphoid tissues…”
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The Integrity of the HMR complex is necessary for centromeric binding and reproductive isolation in Drosophila
Published in PLoS genetics (23-08-2021)“…Postzygotic isolation by genomic conflict is a major cause for the formation of species. Despite its importance, the molecular mechanisms that result in the…”
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10
Liver-resident CD103+ dendritic cells prime antiviral CD8+ T cells in situ
Published in The Journal of immunology (1950) (01-04-2015)“…The liver maintains a tolerogenic environment to avoid unwarranted activation of its resident immune cells upon continuous exposure to food and bacterially…”
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Murine liver‐resident group 1 innate lymphoid cells regulate optimal priming of anti‐viral CD8+ T cells
Published in Journal of leukocyte biology (01-01-2017)“…The liver contains 2 transcriptionally distinct group 1 ILC subsets: CD49a+ ILC1s and CD49b+ NK cells. However, little is known about how group 1 ILCs…”
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Laboratory X-ray Microscopy of 3D Nanostructures in the Hard X-ray Regime Enabled by a Combination of Multilayer X-ray Optics
Published in Nanomaterials (Basel, Switzerland) (01-01-2024)“…High-resolution imaging of buried metal interconnect structures in advanced microelectronic products with full-field X-ray microscopy is demonstrated in the…”
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Laboratory High-Contrast X-ray Microscopy of Copper Nanostructures Enabled by a Liquid-Metal-Jet X-ray Source
Published in Nanomaterials (Basel, Switzerland) (29-02-2024)“…High-resolution imaging of Cu/low-k on-chip interconnect stacks in advanced microelectronic products is demonstrated using full-field transmission X-ray…”
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14
Hepatitis C virus promotes t‐helper (Th)17 responses through thymic stromal lymphopoietin production by infected hepatocytes
Published in Hepatology (Baltimore, Md.) (01-04-2013)“…Hepatitis C virus (HCV) is a major cause of liver cirrhosis and hepatocellular carcinoma. Here we report that infection of hepatic cells by HCV stimulates…”
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15
Principle of Two-Dimensional Characterization of Copolymers
Published in Analytical chemistry (Washington) (01-07-2007)“…Two-dimensional polymer characterization is used for a simultaneous analysis of molar masses and chemical heterogeneities (e.g., end groups, copolymer…”
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Regulation of NK cell repertoire and function in the liver
Published in Critical reviews in immunology (2011)“…NK cells represent a large proportion of the lymphocyte population in the liver and are involved in early innate immunity to pathogen infection. As a result of…”
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3D-interconnect: Visualization of extrusion and voids induced in copper-filled through-silicon vias (TSVs) at various temperatures using X-ray microscopy
Published in Microelectronic engineering (01-04-2012)“…X-ray micrographs compare a 4μm TSV before (A) and after 225°C annealing (B). The copper extrusion and voids-induced at the center of TSV are clearly seen…”
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Boosting corrects a memory B cell defect in SARS-CoV-2 mRNA–vaccinated patients with inflammatory bowel disease
Published in JCI insight (22-06-2022)“…Immunosuppressed patients with inflammatory bowel disease (IBD) generate lower amounts of SARS-CoV-2 spike antibodies after mRNA vaccination than healthy…”
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Ab Initio Studies of Exciton g Factors: Monolayer Transition Metal Dichalcogenides in Magnetic Fields
Published in Physical review letters (05-06-2020)“…The effect of a magnetic field on the optical absorption in semiconductors has been measured experimentally and modeled theoretically for various systems in…”
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Diversity of trion states and substrate effects in the optical properties of an MoS2 monolayer
Published in Nature communications (14-12-2017)“…Almost all experiments and future applications of transition metal dichalcogenide monolayers rely on a substrate for mechanical stability, which can…”
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