Search Results - "Krueger, Annika"

Histone H3K4 monomethylation catalyzed by Trr and mammalian COMPASS-like proteins at enhancers is dispensable for development and viability by Rickels, Ryan, Herz, Hans-Martin, Sze, Christie C, Cao, Kaixiang, Morgan, Marc A, Collings, Clayton K, Gause, Maria, Takahashi, Yoh-hei, Wang, Lu, Rendleman, Emily J, Marshall, Stacy A, Krueger, Annika, Bartom, Elizabeth T, Piunti, Andrea, Smith, Edwin R, Abshiru, Nebiyu A, Kelleher, Neil L, Dorsett, Dale, Shilatifard, Ali

“…Ali Shilatifard and colleagues generate Drosophila lines expressing catalytically deficient Trr, which normally deposits H3K4me1 at enhancers. Trr mutants…”
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An antibiotic from an uncultured bacterium binds to an immutable target by Shukla, Rhythm, Peoples, Aaron J., Ludwig, Kevin C., Maity, Sourav, Derks, Maik G.N., De Benedetti, Stefania, Krueger, Annika M., Vermeulen, Bram J.A., Harbig, Theresa, Lavore, Francesca, Kumar, Raj, Honorato, Rodrigo V., Grein, Fabian, Nieselt, Kay, Liu, Yangping, Bonvin, Alexandre M.J.J., Baldus, Marc, Kubitscheck, Ulrich, Breukink, Eefjan, Achorn, Catherine, Nitti, Anthony, Schwalen, Christopher J., Spoering, Amy L., Ling, Losee Lucy, Hughes, Dallas, Lelli, Moreno, Roos, Wouter H., Lewis, Kim, Schneider, Tanja, Weingarth, Markus

“…Antimicrobial resistance is a leading mortality factor worldwide. Here, we report the discovery of clovibactin, an antibiotic isolated from uncultured soil…”
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Secreted Toxins From Staphylococcus aureus Strains Isolated From Keratinocyte Skin Cancers Mediate Pro-tumorigenic Inflammatory Responses in the Skin by Krueger, Annika, Zaugg, Julian, Chisholm, Sarah, Linedale, Richard, Lachner, Nancy, Teoh, Siok Min, Tuong, Zewen K, Lukowski, Samuel W, Morrison, Mark, Soyer, H Peter, Hugenholtz, Philip, Hill, Michelle M, Frazer, Ian H

“…Squamous cell carcinoma (SCC) is a common type of skin cancer that typically arises from premalignant precursor lesions named actinic keratoses (AK). Chronic…”
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GTPBP8 plays a role in mitoribosome formation in human mitochondria by Cipullo, Miriam, Valentín Gesé, Genís, Gopalakrishna, Shreekara, Krueger, Annika, Lobo, Vivian, Pirozhkova, Maria A., Marks, James, Páleníková, Petra, Shiriaev, Dmitrii, Liu, Yong, Misic, Jelena, Cai, Yu, Nguyen, Minh Duc, Abdelbagi, Abubakar, Li, Xinping, Minczuk, Michal, Hafner, Markus, Benhalevy, Daniel, Sarshad, Aishe A., Atanassov, Ilian, Hällberg, B. Martin, Rorbach, Joanna

“…Mitochondrial gene expression relies on mitoribosomes to translate mitochondrial mRNAs. The biogenesis of mitoribosomes is an intricate process involving…”
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Characterization of the skin microbiome in normal and cutaneous squamous cell carcinoma affected cats and dogs by Bromfield, Jacoba I, Zaugg, Julian, Straw, Rodney C, Cathie, Julia, Krueger, Annika, Sinha, Debottam, Chandra, Janin, Hugenholtz, Philip, Frazer, Ian H

“…Human cutaneous squamous cell carcinomas (SCCs) and actinic keratoses (AK) display microbial dysbiosis with an enrichment of staphylococcal species, which have…”
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Insights into mitoribosomal biogenesis from recent structural studies by Khawaja, Anas, Cipullo, Miriam, Krüger, Annika, Rorbach, Joanna

“…The maturation of mitoribosomes is tightly regulated, and multiple assembly factors facilitate different stages of the process.Recent cryo-EM analyses have…”
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Real-time monitoring of PARP1-dependent PARylation by ATR-FTIR spectroscopy by Krüger, Annika, Bürkle, Alexander, Hauser, Karin, Mangerich, Aswin

“…Poly-ADP-ribosylation (PARylation) is a fully reversible post-translational modification with key roles in cellular physiology. Due to the multi-domain…”
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Interactions of p53 with poly(ADP-ribose) and DNA induce distinct changes in protein structure as revealed by ATR-FTIR spectroscopy by Krüger, Annika, Stier, Anna, Fischbach, Arthur, Bürkle, Alexander, Hauser, Karin, Mangerich, Aswin

“…Abstract Due to multiple domains and in part intrinsically disordered regions, structural analyses of p53 remain a challenging task, particularly in complex…”
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The C-terminal domain of p53 orchestrates the interplay between non-covalent and covalent poly(ADP-ribosyl)ation of p53 by PARP1 by Fischbach, Arthur, Krüger, Annika, Hampp, Stephanie, Assmann, Greta, Rank, Lisa, Hufnagel, Matthias, Stöckl, Martin T, Fischer, Jan M.F, Veith, Sebastian, Rossatti, Pascal, Ganz, Magdalena, Ferrando-May, Elisa, Hartwig, Andrea, Hauser, Karin, Wiesmüller, Lisa, Bürkle, Alexander, Mangerich, Aswin

“…Abstract The post-translational modification poly(ADP-ribosyl)ation (PARylation) plays key roles in genome maintenance and transcription. Both non-covalent…”
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Influence of chain length and branching on poly(ADP-ribose)-protein interactions by Löffler, Tobias, Krüger, Annika, Zirak, Peyman, Winterhalder, Martin J, Müller, Anna-Lena, Fischbach, Arthur, Mangerich, Aswin, Zumbusch, Andreas

“…Hundreds of proteins interact with poly(ADP-ribose) (PAR) via multiple PAR interaction motifs, thereby regulating their physico-chemical properties,…”
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PARP1 catalytic variants reveal branching and chain length-specific functions of poly(ADP-ribose) in cellular physiology and stress response by Aberle, Lisa, Krüger, Annika, Reber, Julia M, Lippmann, Michelle, Hufnagel, Matthias, Schmalz, Michael, Trussina, Irmela R E A, Schlesiger, Sarah, Zubel, Tabea, Schütz, Karina, Marx, Andreas, Hartwig, Andrea, Ferrando-May, Elisa, Bürkle, Alexander, Mangerich, Aswin

“…Abstract Poly(ADP-ribosyl)ation regulates numerous cellular processes like genome maintenance and cell death, thus providing protective functions but also…”
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Antibody-Free Multiplex Measurement of 23 Human Cytokines in Primary Cell Culture Secretome Using Targeted Mass Spectrometry by Krueger, Annika, Stoll, Thomas, Shah, Alok K, Sinha, Rohit, Frazer, Ian H, Hill, Michelle M

“…Cytokines are commonly measured by immunoassays; however, these have limited multiplexing capacity, are costly, and can exhibit cross-reactivity. Multiple…”
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Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time by Ruland, Jan Andreas, Krüger, Annika Marie, Dörner, Kerstin, Bhatia, Rohan, Wirths, Sabine, Poetes, Daniel, Kutay, Ulrike, Siebrasse, Jan Peter, Kubitscheck, Ulrich

“…Ribosomal biogenesis has been studied by biochemical, genetic and electron microscopic approaches, but live cell data on the in vivo kinetics are still…”
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Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action by Puls, Jan-Samuel, Winnerling, Benjamin, Power, Jeffrey John, Krüger, Annika Marie, Brajtenbach, Dominik, Johnson, Matthew, Bilici, Kevser, Camus, Laura, Fließwasser, Thomas, Schneider, Tanja, Sahl, Hans-Georg, Ghosal, Debnath, Kubitscheck, Ulrich, Heilbronner, Simon, Grein, Fabian

“…Many bacteria produce antimicrobial compounds such as lantibiotics to gain advantage in the competitive natural environments of microbiomes. Epilancins…”
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Skin Cancer-Associated S. aureus Strains Can Induce DNA Damage in Human Keratinocytes by Downregulating DNA Repair and Promoting Oxidative Stress by Krueger, Annika, Mohamed, Ahmed, Kolka, Cathryn M, Stoll, Thomas, Zaugg, Julian, Linedale, Richard, Morrison, Mark, Soyer, H Peter, Hugenholtz, Philip, Frazer, Ian H, Hill, Michelle M

“…Actinic keratosis (AK) is a premalignant lesion, common on severely photodamaged skin, that can progress over time to cutaneous squamous cell carcinoma (SCC)…”
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Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo by Schuhwerk, Harald, Bruhn, Christopher, Siniuk, Kanstantsin, Min, Wookee, Erener, Suheda, Grigaravicius, Paulius, Krüger, Annika, Ferrari, Elena, Zubel, Tabea, Lazaro, David, Monajembashi, Shamci, Kiesow, Kirstin, Kroll, Torsten, Bürkle, Alexander, Mangerich, Aswin, Hottiger, Michael, Wang, Zhao-Qi

“…One of the fastest cellular responses to genotoxic stress is the formation of poly(ADP-ribose) polymers (PAR) by poly(ADP-ribose)polymerase 1 (PARP1, or…”
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Changes in the skin microbiome associated with squamous cell carcinoma in transplant recipients by Krueger, Annika, Zaugg, Julian, Lachner, Nancy, Bialasiewicz, Seweryn, Lin, Lynlee L, Gabizon, Sharon, Sobarun, Priyamvada, Morrison, Mark, Soyer, H Peter, Hugenholtz, Philip, Frazer, Ian H

“…Abstract Actinic keratoses (AK) arise in severely photo-damaged skin and can progress to squamous cell carcinomas (SCC). AK and SCC are common in Caucasian…”
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2125. Staphylococcus Species Identification by Fourier Transform Infrared (FTIR) Spectroscopic Techniques: A Cross-Lab Study by Tsutsumi, Tamao, Shah, Alok, Lam, Lisa M T, Schlebusch, Sanmarie, Krueger, Annika, Frazer, Ian, Hugenholtz, Phil, Soyer, H Peter, Morrison, Mark, Hill, Michelle, Sedman, Jacqueline, Ismail, Ashraf

“…Abstract Background Staphylococcus aureus is well known to be associated with atopic dermatitis. Recent studies also report S. aureus presence in lesional skin…”
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