Search Results - "Kruegel, Brian R"

Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating “clinical proof-of-concept” for AAV-neurturin (CERE-120) in Parkinson's disease by Bartus, Raymond T, Baumann, Tiffany L, Brown, Lamar, Kruegel, Brian R, Ostrove, Jeffrey M, Herzog, Christopher D

“…Abstract Neurotrophic factors have long shown promise as potential therapies for age-related neurodegenerative diseases. However, 20 years of largely…”
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Enhanced neurotrophic distribution, cell signaling and neuroprotection following substantia nigral versus striatal delivery of AAV2-NRTN (CERE-120) by Herzog, Christopher D, Brown, Lamar, Kruegel, Brian R, Wilson, Alistair, Tansey, Malú G, Gage, Fred H, Johnson, Eugene M, Bartus, Raymond T

“…Abstract This paper reassesses the currently accepted viewpoint that targeting the terminal fields (i.e. striatum) of degenerating nigrostriatal dopamine…”
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Advancing neurotrophic factors as treatments for age-related neurodegenerative diseases: developing and demonstrating aclinical proof-of-concepta for AAV-neurturin (CERE-120) in Parkinson's disease by Bartus, Raymond T, Baumann, Tiffany L, Brown, Lamar, Kruegel, Brian R, Ostrove, Jeffrey M, Herzog, Christopher D

“…Neurotrophic factors have long shown promise as potential therapies for age-related neurodegenerative diseases. However, 20 years of largely disappointing…”
Get full text