Search Results - "Krstić, Natalija M."
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1
Steroid dimers-in vitro cytotoxic and antimicrobial activities
Published in The Journal of steroid biochemistry and molecular biology (01-09-2014)“…The in vitro cytotoxic activity of previously synthesized steroid dimers with different spacer group (sulfide, trithiolane ring or phosphorotrithioate) and the…”
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2
Anticancer potential of new steroidal thiazolidin-4-one derivatives. Mechanisms of cytotoxic action and effects on angiogenesis in vitro
Published in The Journal of steroid biochemistry and molecular biology (01-11-2017)“…•The synthesis of new steroidal mono- and bis(thiazolidin-4-ones) was performed.•Pro-apoptotic action of 4a and 5a on HeLa cells.•Apoptosis in HeLa cells…”
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3
Synthesis of some steroidal oximes, lactams, thiolactams and their antitumor activities
Published in Steroids (01-05-2007)“…The antiproliferative activity of previously synthesized ( Z)-cholest-4-en-6-one oxime ( 1), ( E)-cholest-4-en-6-one oxime ( 2), 7-aza-B-homocholest-4-en-6-one…”
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4
Thionation of some alpha,beta-unsaturated steroidal ketones
Published in Molecules (Basel, Switzerland) (12-05-2010)“…The reactions of selected alpha,beta-unsaturated steroidal ketones with Lawesson's reagent (LR) in CH(2)Cl(2) and toluene under the standard reaction…”
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5
Synthesis, characterization and biological evaluation of some novel P-heterocyclic androst-4-ene derivatives
Published in Molecular diversity (01-08-2013)“…The reactions of 21-hydroxyprogesterone with Lawesson’s reagent in toluene or CH 2 Cl 2 gave four P-heterocyclic androst-4-ene derivatives (two tautomeric…”
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6
Synthesis and preliminary screening for the biological activity of some steroidal Δ4-unsaturated semicarbazone derivatives
Published in Steroids (01-08-2019)“…•The synthesis of new steroidal mono- and bis(semicarbazones) was performed.•The new carbazate esters were obtained.•The structures were determined by IR, NMR,…”
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7
New androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. Synthesis, assignment of absolute configuration and in vitro cytotoxic and antimicrobial activities
Published in Steroids (01-04-2012)“…[Display omitted] ► Simple syntheses of the new androst-4-en-17-spiro-1,3,2-oxathiaphospholanes. ► The structures and absolute configurations were determined…”
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8
Synthesis, characterization and biological activity of Pt(II) complexes with steroidal thiosemicarbazones
Published in Journal of the Serbian Chemical Society (2021)“…In this work, Pt(II) complexes of previously synthesized steroidal thiosemicarbazones were synthesized and characterized. The ligands and their metal complexes…”
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9
Oxidative 10-membered ring expansion and contraction of stereoisomeric 1(10)-unsaturated and 1,10-epoxy-5-oxo-5,10-secosteroids induced by peracids
Published in Tetrahedron (09-09-2012)“…The present study is concerned with the oxidative behaviour of unsaturated and epoxy 5-oxo-5,10-secosteroids in the presence of m-CPBA or TFAA-UHP as oxidants…”
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10
5,10:13,14-Disecosteroids: novel modified steroids containing 10- and 9-membered rings
Published in Tetrahedron (14-11-2009)“…In this paper a synthetic pathway to the modified 5,10:13,14-bisfragmentation cholestane derivatives 8– 14 is described. The synthesis involves introduction of…”
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11
Steroid template associated peptides: design, synthesis and 2D NMR characterization of a novel protected 18-Phe,19-Gly-containing steroidal compound
Published in Tetrahedron (01-10-2007)“…We report herein the synthesis of a novel modified steroid with two rigidly positioned amino acids in C- and N-protected forms (Gly–O t Bu and N-Fmoc– l-Phe)…”
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12
Conformations of the Nine-Membered Ring in the B-Nor-5,10-secosteroids. X-Ray and NMR Analysis
Published in Helvetica chimica acta (01-10-2005)“…The conformations of (Z)‐ and (E)‐5‐oxo‐B‐nor‐5,10‐secocholest‐1(10)‐en‐3β‐yl acetates (2 and 3, resp.) were examined by a combination of X‐ray…”
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13
Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime
Published in Journal of the Serbian Chemical Society (01-01-2004)“…Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime (4) (prepared in 4 steps starting from cholest-5-en-3β-ol ο1)) with thionyl chloride in dioxane solution…”
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14
Synthesis and preliminary screening for the biological activity of some steroidal Δ 4 -unsaturated semicarbazone derivatives
Published in Steroids (01-08-2019)“…Eleven new steroidal mono- and bis(semicarbazones) 2a-e, 4d and 3a-e have been prepared starting from various 3-oxo-α,β-unsaturated steroids…”
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15
Peracids oxidation of cholesta-5,8-dien-3β-yl acetate
Published in Journal of the Serbian Chemical Society (01-01-2000)“…Expoxidation of cholesta-5,8-dien-3β-yl acetate (1) with peracids takes place preferentially at the more highly substituted Δ8-olefinic double bond to give:…”
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16
Oxidative fragmentation of 5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate
Published in Journal of the Serbian Chemical Society (01-01-2003)“…5-hydroxy-1-oxo-5α-cholestan-3β-yl acetate (11) was prepared in 5 steps starting from (E)-3β-acetoxy-5,10-seco-1(10)-cholesten-5-one (6). Treatment of the…”
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17
Thionation of Some [alpha],[beta]-Unsaturated Steroidal Ketones
Published in Molecules (Basel, Switzerland) (01-05-2010)“…The reactions of selected α,β-unsaturated steroidal ketones with Lawesson's reagent (LR) in CH2Cl2 and toluene under the standard reaction conditions and with…”
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18
Photochemical and Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime
Published in Journal of the Serbian Chemical Society (01-06-2004)“…Beckmann rearrangement of (Z)-cholest-4-en-6-one oxime (4) (prepared in 4 steps starting from cholest-5-en-3b-ol (1)) with thionyl chloride in dioxane solution…”
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19
Oxidative fragmentations of 5-hydroxy-1-oxo-5alpha-cholestan-3beta-yl acetate
Published in Journal of the Serbian Chemical Society (01-11-2003)“…5-Hydroxy-1-oxo-5a-cholestan-3b-yl acetate (11) was prepared in 5 steps starting from (E)-3b-acetoxy-5,10-seco-1(10)-cholesten-5-one (6). Treatment of the…”
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20
Peracids oxidation of cholesta-5,8-dien-3b-yl acetate
Published in Journal of the Serbian Chemical Society (01-11-2000)“…Expoxidation of cholesta-5,8-dien-3b-yl acetate (1) with peracids takes place preferentially at the more highly substituted D8-olefinic double bond to give:…”
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