Search Results - "Krskova, Lenka"

Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas by Guerreiro Stucklin, Ana S., Ryall, Scott, Fukuoka, Kohei, Zapotocky, Michal, Lassaletta, Alvaro, Li, Christopher, Bridge, Taylor, Kim, Byungjin, Arnoldo, Anthony, Kowalski, Paul E., Zhong, Yvonne, Johnson, Monique, Li, Claire, Ramani, Arun K., Siddaway, Robert, Nobre, Liana Figueiredo, de Antonellis, Pasqualino, Dunham, Christopher, Cheng, Sylvia, Boué, Daniel R., Finlay, Jonathan L., Coven, Scott L., de Prada, Inmaculada, Perez-Somarriba, Marta, Faria, Claudia, Grotzer, Michael A., Rushing, Elisabeth, Sumerauer, David, Zamecnik, Josef, Krskova, Lenka, Garcia Ariza, Miguel, Cruz, Ofelia, Morales La Madrid, Andres, Solano, Palma, Terashima, Keita, Nakano, Yoshiko, Ichimura, Koichi, Nagane, Motoo, Sakamoto, Hiroaki, Gil-da-Costa, Maria Joao, Silva, Roberto, Johnston, Donna L., Michaud, Jean, Wilson, Bev, van Landeghem, Frank K. H., Oviedo, Angelica, McNeely, P. Daniel, Crooks, Bruce, Fried, Iris, Zhukova, Nataliya, Hansford, Jordan R., Nageswararao, Amulya, Garzia, Livia, Shago, Mary, Brudno, Michael, Irwin, Meredith S., Bartels, Ute, Ramaswamy, Vijay, Bouffet, Eric, Taylor, Michael D., Tabori, Uri, Hawkins, Cynthia

“…© The Author(s) 2019. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing,…”
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CIC::NUTM1 sarcoma in a 6‐year‐old male patient arising from the choroid plexus of the lateral ventricle: A case report by Jan, Balko, Filip, Kukla, Lenka, Krskova, Lucia, Janigova, Petr, Broz, Josef, Zamecnik

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Therapeutic and Prognostic Implications of BRAF V600E in Pediatric Low-Grade Gliomas by Lassaletta, Alvaro, Zapotocky, Michal, Mistry, Matthew, Ramaswamy, Vijay, Honnorat, Marion, Krishnatry, Rahul, Guerreiro Stucklin, Ana, Zhukova, Nataliya, Arnoldo, Anthony, Ryall, Scott, Ling, Catriona, McKeown, Tara, Loukides, Jim, Cruz, Ofelia, de Torres, Carmen, Ho, Cheng-Ying, Packer, Roger J, Tatevossian, Ruth, Qaddoumi, Ibrahim, Harreld, Julie H, Dalton, James D, Mulcahy-Levy, Jean, Foreman, Nicholas, Karajannis, Matthias A, Wang, Shiyang, Snuderl, Matija, Nageswara Rao, Amulya, Giannini, Caterina, Kieran, Mark, Ligon, Keith L, Garre, Maria Luisa, Nozza, Paolo, Mascelli, Samantha, Raso, Alessandro, Mueller, Sabine, Nicolaides, Theodore, Silva, Karen, Perbet, Romain, Vasiljevic, Alexandre, Faure Conter, Cécile, Frappaz, Didier, Leary, Sarah, Crane, Courtney, Chan, Aden, Ng, Ho-Keung, Shi, Zhi-Feng, Mao, Ying, Finch, Elizabeth, Eisenstat, David, Wilson, Bev, Carret, Anne Sophie, Hauser, Peter, Sumerauer, David, Krskova, Lenka, Larouche, Valerie, Fleming, Adam, Zelcer, Shayna, Jabado, Nada, Rutka, James T, Dirks, Peter, Taylor, Michael D, Chen, Shiyi, Bartels, Ute, Huang, Annie, Ellison, David W, Bouffet, Eric, Hawkins, Cynthia, Tabori, Uri

“…Purpose BRAF V600E is a potentially highly targetable mutation detected in a subset of pediatric low-grade gliomas (PLGGs). Its biologic and clinical effect…”
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A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR by Sievers, Philipp, Sill, Martin, Schrimpf, Daniel, Stichel, Damian, Reuss, David E, Sturm, Dominik, Hench, Jürgen, Frank, Stephan, Krskova, Lenka, Vicha, Ales, Zapotocky, Michal, Bison, Brigitte, Castel, David, Grill, Jacques, Debily, Marie-Anne, Harter, Patrick N, Snuderl, Matija, Kramm, Christof M, Reifenberger, Guido, Korshunov, Andrey, Jabado, Nada, Wesseling, Pieter, Wick, Wolfgang, Solomon, David A, Perry, Arie, Jacques, Thomas S, Jones, Chris, Witt, Olaf, Pfister, Stefan M, von Deimling, Andreas, Jones, David T W, Sahm, Felix

“…Abstract Background Malignant astrocytic gliomas in children show a remarkable biological and clinical diversity. Small in-frame insertions or missense…”
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PATZ1 fusions define a novel molecularly distinct neuroepithelial tumor entity with a broad histological spectrum by Alhalabi, Karam T., Stichel, Damian, Sievers, Philipp, Peterziel, Heike, Sommerkamp, Alexander C., Sturm, Dominik, Wittmann, Andrea, Sill, Martin, Jäger, Natalie, Beck, Pengbo, Pajtler, Kristian W., Snuderl, Matija, Jour, George, Delorenzo, Michael, Martin, Allison M., Levy, Adam, Dalvi, Nagma, Hansford, Jordan R., Gottardo, Nicholas G., Uro-Coste, Emmanuelle, Maurage, Claude-Alain, Godfraind, Catherine, Vandenbos, Fanny, Pietsch, Torsten, Kramm, Christof, Filippidou, Maria, Kattamis, Antonis, Jones, Chris, Øra, Ingrid, Mikkelsen, Torben Stamm, Zapotocky, Michal, Sumerauer, David, Scheie, David, McCabe, Martin, Wesseling, Pieter, Tops, Bastiaan B. J., Kranendonk, Mariëtte E. G., Karajannis, Matthias A., Bouvier, Nancy, Papaemmanuil, Elli, Dohmen, Hildegard, Acker, Till, von Hoff, Katja, Schmid, Simone, Miele, Evelina, Filipski, Katharina, Kitanovski, Lidija, Krskova, Lenka, Gojo, Johannes, Haberler, Christine, Alvaro, Frank, Ecker, Jonas, Selt, Florian, Milde, Till, Witt, Olaf, Oehme, Ina, Kool, Marcel, von Deimling, Andreas, Korshunov, Andrey, Pfister, Stefan M., Sahm, Felix, Jones, David T. W.

“…Large-scale molecular profiling studies in recent years have shown that central nervous system (CNS) tumors display a much greater heterogeneity in terms of…”
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MIAT Is an Upstream Regulator of NMYC and the Disruption of the MIAT/NMYC Axis Induces Cell Death in NMYC Amplified Neuroblastoma Cell Lines by Feriancikova, Barbara, Feglarova, Tereza, Krskova, Lenka, Eckschlager, Tomas, Vicha, Ales, Hrabeta, Jan

“…Neuroblastoma (NBL) is the most common extracranial childhood malignant tumor and represents a major cause of cancer-related deaths in infants. amplification…”
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Recurrent fusions in PLAGL1 define a distinct subset of pediatric-type supratentorial neuroepithelial tumors by Sievers, Philipp, Henneken, Sophie C., Blume, Christina, Sill, Martin, Schrimpf, Daniel, Stichel, Damian, Okonechnikov, Konstantin, Reuss, David E., Benzel, Julia, Maaß, Kendra K., Kool, Marcel, Sturm, Dominik, Zheng, Tuyu, Ghasemi, David R., Kohlhof-Meinecke, Patricia, Cruz, Ofelia, Suñol, Mariona, Lavarino, Cinzia, Ruf, Viktoria, Boldt, Henning B., Pagès, Mélanie, Pouget, Celso, Schweizer, Leonille, Kranendonk, Mariëtte E. G., Akhtar, Noreen, Bunkowski, Stephanie, Stadelmann, Christine, Schüller, Ulrich, Mueller, Wolf C., Dohmen, Hildegard, Acker, Till, Harter, Patrick N., Mawrin, Christian, Beschorner, Rudi, Brandner, Sebastian, Snuderl, Matija, Abdullaev, Zied, Aldape, Kenneth, Gilbert, Mark R., Armstrong, Terri S., Ellison, David W., Capper, David, Ichimura, Koichi, Reifenberger, Guido, Grundy, Richard G., Jabado, Nada, Krskova, Lenka, Zapotocky, Michal, Vicha, Ales, Varlet, Pascale, Wesseling, Pieter, Rutkowski, Stefan, Korshunov, Andrey, Wick, Wolfgang, Pfister, Stefan M., Jones, David T. W., von Deimling, Andreas, Pajtler, Kristian W., Sahm, Felix

“…Ependymomas encompass a heterogeneous group of central nervous system (CNS) neoplasms that occur along the entire neuroaxis. In recent years, extensive…”
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Unusual case of inflammatory rhabdomyoblastic tumor in a pediatric patient by Krsková, Lenka, Šípalová, Barbora, Balko, Jan, Zimová, Simona, Voříšková, Dagmar, Brož, Petr, Kodet, Roman, Vícha, Aleš

“…Inflammatory rhabdomyoblastic tumor (IRMT) is a rare, recently described skeletal muscle neoplasm of uncertain malignant potential. We report an unusual tumor…”
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Clinical Features, Neuropathology, and Surgical Outcome in Patients With Refractory Epilepsy and Brain Somatic Variants in the SLC35A2 Gene by Barba, Carmen, Blumcke, Ingmar, Winawer, Melodie R., Hartlieb, Till, Kang, Hoon-Chul, Grisotto, Laura, Chipaux, Mathilde, Bien, Christian G., Heřmanovská, Barbora, Porter, Brenda E., Lidov, Hart G.W., Cetica, Valentina, Woermann, Friedrich G., Lopez-Rivera, Javier A., Canoll, Peter D., Mader, Irina, D'Incerti, Ludovico, Baldassari, Sara, Yang, Edward, Gaballa, Ahmed, Vogel, Hannes, Straka, Barbora, Macconi, Letizia, Polster, Tilman, Grant, Gerald A., Krsková, Lenka, Shin, Hui Jin, Ko, Ara, Crino, Peter B., Krsek, Pavel, Lee, Jeong Ho, Lal, Dennis, Baulac, Stéphanie, Poduri, Annapurna, Guerrini, Renzo

“…The gene, located at chromosome Xp11.23, encodes for a uridine diphosphate-galactose transporter. We describe clinical, genetic, neuroimaging, EEG, and…”
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Patient with composite haemangioendothelioma containing angiosarcoma-like areas in the setting of congenital lymphoedema mimicking Stewart-Treves syndrome: a case report by Balko, Jan, Ozaniak, Andrej, Krskova, Lenka, Strizova, Zuzana, Lischke, Robert, Zamecnik, Josef

“…Composite haemangioendothelioma is a rare vascular neoplasm with indolent to intermediate malignant potential. Diagnosis of this disease relays on…”
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Mazabraud's syndrome: A case report supported by molecular studies and review of the literature by Kašpar, Ludvík, Balko, Jan, Strnadová, Martina, Krsková, Lenka, Máška, David, Zámečník, Josef

“…Mazabraud's syndrome represents rare benign disorder characterized by simultaneous occurrence of fibrous dysplasia of bone and intramuscular myxomas within…”
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Clinical and molecular study of radiation-induced gliomas by Trkova, Katerina, Sumerauer, David, Bubenikova, Adela, Krskova, Lenka, Vicha, Ales, Koblizek, Miroslav, Zamecnik, Josef, Jurasek, Bruno, Kyncl, Martin, Malinova, Bela, Ondrova, Barbora, Jones, David T. W., Sill, Martin, Strnadova, Martina, Stolova, Lucie, Misove, Adela, Benes, Vladimir, Zapotocky, Michal

“…In this study, we provide a comprehensive clinical and molecular biological characterization of radiation-induced gliomas (RIG), including a risk assessment…”
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Rare IDH1 variants are common in pediatric hemispheric diffuse astrocytomas and frequently associated with Li-Fraumeni syndrome by Sumerauer, David, Krskova, Lenka, Vicha, Ales, Misove, Adela, Mamatjan, Yasin, Jencova, Pavla, Vlckova, Marketa, Slamova, Lucie, Vanova, Katerina, Liby, Petr, Taborsky, Jakub, Koblizek, Miroslav, Klubal, Radek, Kyncl, Martin, Zadeh, Gelareh, Stary, Jan, Zamecnik, Josef, Ramaswamy, Vijay, Zapotocky, Michal

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Integrated genomic analysis reveals actionable targets in pediatric spinal cord low-grade gliomas by Misove, Adela, Vicha, Ales, Broz, Petr, Vanova, Katerina, Sumerauer, David, Stolova, Lucie, Sramkova, Lucie, Koblizek, Miroslav, Zamecnik, Josef, Kyncl, Martin, Holubova, Zuzana, Liby, Petr, Taborsky, Jakub, Benes, 3rd, Vladimir, Pernikova, Ivana, Jones, David T W, Sill, Martin, Stancokova, Terezia, Krskova, Lenka, Zapotocky, Michal

“…Gliomas are the most common central nervous tumors in children and adolescents. However, spinal cord low-grade gliomas (sLGGs) are rare, with scarce…”
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Differential patterns of metastatic dissemination across medulloblastoma subgroups by Zapotocky, Michal, Mata-Mbemba, Daddy, Sumerauer, David, Liby, Petr, Lassaletta, Alvaro, Zamecnik, Josef, Krskova, Lenka, Kyncl, Martin, Stary, Jan, Laughlin, Suzanne, Arnoldo, Anthony, Hawkins, Cynthia, Tabori, Uri, Taylor, Michael D, Bouffet, Eric, Raybaud, Charles, Ramaswamy, Vijay

“…OBJECTIVE Metastatic dissemination is a major treatment challenge and cause of death in patients with medulloblastoma. However, the influence of molecular…”
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Clinicogenomic associations in childhood Langerhans cell histiocytosis: an international cohort study by Kemps, Paul G., Zondag, Timo C. E., Arnardóttir, Helga B., Solleveld-Westerink, Nienke, Borst, Jelske, Steenwijk, Eline C., van Egmond, Demi, Swennenhuis, Joost F., Stelloo, Ellen, Trambusti, Irene, Verdijk, Robert M., van Noesel, Carel J. M., Cleven, Arjen H. G., Scheijde-Vermeulen, Marijn A., Koudijs, Marco J., Krsková, Lenka, Hawkins, Cynthia, Egeler, R. Maarten, Brok, Jesper, von Bahr Greenwood, Tatiana, Svojgr, Karel, Beishuizen, Auke, van Laar, Jan A. M., Pötschger, Ulrike, Hutter, Caroline, Sieni, Elena, Minkov, Milen, Abla, Oussama, van Wezel, Tom, van den Bos, Cor, van Halteren, Astrid G. S.

“…•Oncogenic mutation subtype appears an important driver of heterogeneity in clinical presentation of pediatric LCH.•Lesional BRAFV600E status is not a…”
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A novel quantitative PCR of proliferation markers (Ki-67, topoisomerase IIα, and TPX2): an immunohistochemical correlation, testing, and optimizing for mantle cell lymphoma by Brizova, Helena, Kalinova, Marketa, Krskova, Lenka, Mrhalova, Marcela, Kodet, Roman

“…A clinical course of patients with mantle cell lymphoma (MCL) is aggressive, and the disease is rarely curable. Proliferation rate is the most important…”
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Correction to: Integrated genomic analysis reveals actionable targets in pediatric spinal cord low-grade gliomas by Misove, Adela, Vicha, Ales, Broz, Petr, Vanova, Katerina, Sumerauer, David, Stolova, Lucie, Sramkova, Lucie, Koblizek, Miroslav, Zamecnik, Josef, Kyncl, Martin, Holubova, Zuzana, Liby, Petr, Taborsky, Jakub, Benes, 3rd, Vladimir, Pernikova, Ivana, Jones, David T W, Sill, Martin, Stancokova, Terezia, Krskova, Lenka, Zapotocky, Michal

“…Prague Brain Tumor Research Group, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic Adela Misove, Ales…”
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Pattern of Relapse and Treatment Response in WNT-Activated Medulloblastoma by Nobre, Liana, Zapotocky, Michal, Khan, Sara, Fukuoka, Kohei, Fonseca, Adriana, McKeown, Tara, Sumerauer, David, Vicha, Ales, Grajkowska, Wieslawa A., Trubicka, Joanna, Li, Kay Ka Wai, Ng, Ho-Keung, Massimi, Luca, Lee, Ji Yeoun, Kim, Seung-Ki, Zelcer, Shayna, Vasiljevic, Alexandre, Faure-Conter, Cécile, Hauser, Peter, Lach, Boleslaw, van Veelen-Vincent, Marie-Lise, French, Pim J., Van Meir, Erwin G., Weiss, William A., Gupta, Nalin, Pollack, Ian F., Hamilton, Ronald L., Nageswara Rao, Amulya A., Giannini, Caterina, Rubin, Joshua B., Moore, Andrew S., Chambless, Lola B., Vibhakar, Rajeev, Ra, Young Shin, Massimino, Maura, McLendon, Roger E., Wheeler, Helen, Zollo, Massimo, Ferruci, Veronica, Kumabe, Toshihiro, Faria, Claudia C., Sterba, Jaroslav, Jung, Shin, López-Aguilar, Enrique, Mora, Jaume, Carlotti, Carlos G., Olson, James M., Leary, Sarah, Cain, Jason, Krskova, Lenka, Zamecnik, Josef, Hawkins, Cynthia E., Tabori, Uri, Huang, Annie, Bartels, Ute, Northcott, Paul A., Taylor, Michael D., Yip, Stephen, Hansford, Jordan R., Bouffet, Eric, Ramaswamy, Vijay

“…Over the past decade, wingless-activated (WNT) medulloblastoma has been identified as a candidate for therapy de-escalation based on excellent survival;…”
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Novel ZEB2‐PLAG1 fusion gene identified by RNA sequencing in a case of lipoblastoma by Krsková, Lenka, Němečková, Tereza, Balko, Jan, Brož, Petr, Vícha, Aleš

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