Search Results - "Kroustkova, Jana"
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Undescribed Amaryllidaceae Alkaloids from Zephyranthes citrina and Their Cytotoxicity
Published in Journal of natural products (Washington, D.C.) (27-09-2024)“…This phytochemical study presents the isolation of eight alkaloids from Zephyranthes citrina Baker. The structures of the new alkaloids, zephycitrine (1) and…”
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Antiproliferative activity and apoptosis-inducing mechanism of Amaryllidaceae alkaloid montanine on A549 and MOLT-4 human cancer cells
Published in Biomedicine & pharmacotherapy (01-10-2023)“…The isoquinoline alkaloids found in Amaryllidaceae are attracting attention due to attributes that can be harnessed for the development of new drugs. The…”
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Specialized metabolites of the genus Zephyranthes Herb.: a critical review on taxonomy and phytochemistry
Published in Phytochemistry reviews (26-06-2024)“…This article is a critical review of the taxonomy and phytochemistry of the genus Zephyranthes Herb., a group of plants known for their beautiful flowers and…”
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Structural analysis of unusual alkaloids isolated from Narcissus pseudonarcissus cv. Carlton
Published in Phytochemistry (Oxford) (01-12-2022)“…Narciindole A, the first representative of Amaryllidaceae alkaloids with an indol-3-ylmethanone framework, was isolated from bulbs of Narcissus pseudonarcissus…”
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Design of semisynthetic derivatives of the Amaryllidaceae alkaloid ambelline and exploration of their in vitro cytotoxic activities
Published in Saudi pharmaceutical journal (01-08-2023)“…Ambelline, an alkaloid from the Amaryllidaceae family with a crinane-type skeleton, has not yet demonstrated any outstanding biological activity. However, its…”
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Semisynthetic derivatives of haemanthamine and their in vitro antiproliferative activity evaluation against a panel of human cell lines
Published in Arabian journal of chemistry (01-05-2022)“…[Display omitted] In this study, a new series of aliphatic, cyclic, and heterocyclic derivatives of haemanthamine was designed and synthesized to enhance its…”
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Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of Plasmodium berghei Infection In Vitro
Published in Pharmaceutics (21-03-2023)“…The incidence rate of malaria and the ensuing mortality prompts the development of novel antimalarial drugs. In this work, the activity of twenty-eight…”
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Amaryllidaceae Alkaloids from Clivia miniata (Lindl.) Bosse (Amaryllidaceae): Isolation, Structural Elucidation, and Biological Activity
Published in Plants (Basel) (10-11-2022)“…(Amaryllidaceae) is an herbaceous evergreen flowering plant that is endemic to South Africa and Swaziland and belongs to one of the top-10 traded medicinal…”
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Alkaloids of Dicranostigma franchetianum (Papaveraceae) and Berberine Derivatives as a New Class of Antimycobacterial Agents
Published in Biomolecules (Basel, Switzerland) (17-06-2022)“…Tuberculosis (TB) is a widespread infectious disease caused by Mycobacterium tuberculosis. The increasing incidence of multidrug-resistant (MDR) and…”
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Highly selective butyrylcholinesterase inhibitors related to Amaryllidaceae alkaloids - Design, synthesis, and biological evaluation
Published in European journal of medicinal chemistry (05-04-2023)“…Butyrylcholinesterase (BChE) is one of the most frequently implicated enzymes in the advanced stage of Alzheimer's disease (AD). As part of our endeavors to…”
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Derivatives of Amaryllidaceae Alkaloid Ambelline as Selective Inhibitors of Hepatic Stage of IPlasmodium berghei/I Infection In Vitro
Published in Pharmaceutics (01-03-2023)“…The incidence rate of malaria and the ensuing mortality prompts the development of novel antimalarial drugs. In this work, the activity of twenty-eight…”
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Amaryllidaceae Alkaloids from IClivia miniata/I : Isolation, Structural Elucidation, and Biological Activity
Published in Plants (Basel) (01-11-2022)“…Clivia miniata (Amaryllidaceae) is an herbaceous evergreen flowering plant that is endemic to South Africa and Swaziland and belongs to one of the top-10…”
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