Search Results - "Krotulski, Alex"

Medetomidine Infiltrates the US Illicit Opioid Market by Palamar, Joseph J, Krotulski, Alex J

“…This Viewpoint discusses the spread of medetomidine in the US illicit opioid market and the need for monitoring and a public health response…”
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The next generation of synthetic cannabinoids: Detection, activity, and potential toxicity of pent‐4en and but‐3en analogues including MDMB‐4en‐PINACA by Krotulski, Alex J., Cannaert, Annelies, Stove, Christophe, Logan, Barry K.

“…A new class of synthetic cannabinoids has emerged as new psychoactive substances (NPS). Similar in structure to JWH‐022, these substances contain alkene…”
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Isotonitazene Quantitation and Metabolite Discovery in Authentic Forensic Casework by Krotulski, Alex J, Papsun, Donna M, Kacinko, Sherri L, Logan, Barry K

“…The synthetic opioid landscape continues to change as non-fentanyl-related substances appear in forensic toxicology casework. Among the newest synthetic…”
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A Forward-Thinking Approach to Addressing the New Synthetic Opioid 2-Benzylbenzimidazole Nitazene Analogs by Liquid Chromatography–Tandem Quadrupole Mass Spectrometry (LC–QQQ-MS) by Walton, Sara E, Krotulski, Alex J, Logan, Barry K

“…Abstract Novel psychoactive substances (NPS) continue to represent a threat to public health and safety. The number of new drugs in the latest emergent…”
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Sample Mining and Data Mining: Combined Real‐Time and Retrospective Approaches for the Identification of Emerging Novel Psychoactive Substances by Krotulski, Alex J., Varnum, Susan Jansen, Logan, Barry K.

“…Novel psychoactive substances (NPS) are synthetic drugs that pose serious public health and safety concerns. A multitude of NPS have been identified in the…”
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Identification of ADB-5’Br-BINACA in plant material and analytical characterization using GC-MS, LC-QTOF-MS, NMR and ATR-FTIR by de Campos, Eduardo G., Farrar, David G., Krotulski, Alex J.

“…Synthetic cannabinoids are a class of novel psychoactive substances that emerged in the drug market in the early 2010s. Since then, a wide range of different…”
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Proliferation of Novel Synthetic Opioids in Postmortem Investigations After Core-Structure Scheduling for Fentanyl-Related Substances by Papsun, Donna M., Krotulski, Alex J., Logan, Barry K.

“…New generations of novel synthetic opioids (NSOs) have emerged to fill a void in the illicit drug markets left by the decline in popularity of fentanyl analogs…”
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Detection, chemical analysis, and pharmacological characterization of dipyanone and other new synthetic opioids related to prescription drugs by Vandeputte, Marthe M., Walton, Sara E., Shuda, Sarah A., Papsun, Donna M., Krotulski, Alex J., Stove, Christophe P.

“…The emergence of structurally diverse new synthetic opioids (NSOs) has caused the opioid crisis to spiral to new depths. Little information is available about…”
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Metonitazene in the United States—Forensic toxicology assessment of a potent new synthetic opioid using liquid chromatography mass spectrometry by Krotulski, Alex J., Papsun, Donna M., Walton, Sara E., Logan, Barry K.

“…Metonitazene is considered a new psychoactive substance (NPS) and emerging potent synthetic opioid, causing increased public health concern beginning in 2020…”
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Emerging Synthetic Cannabinoids: Development and Validation of a Novel Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry Assay for Real-Time Detection by Krotulski, Alex J, Mohr, Amanda L A, Logan, Barry K

“…Abstract Synthetic cannabinoids pose significant threats to public health and safety, as their implications in overdose and adverse events continue to arise in…”
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The Rise and Fall of Isotonitazene and Brorphine: Two Recent Stars in the Synthetic Opioid Firmament by Vandeputte, Marthe M, Krotulski, Alex J, Papsun, Donna M, Logan, Barry K, Stove, Christophe P

“…Abstract Synthetic opioids constitute one of the fastest-growing groups of new psychoactive substances (NPS) worldwide. With fentanyl analogues being…”
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Detection of Cutting Agents in Drug‐Positive Seized Exhibits within the United States by Fiorentin, Taís R., Krotulski, Alex J., Martin, David M., Browne, Thom, Triplett, Jeremy, Conti, Trisha, Logan, Barry K.

“…The following report summarizes a study performed on seized drug exhibits collected in two U.S. states to evaluate the presence and identification of cutting…”
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Brorphine—Investigation and quantitation of a new potent synthetic opioid in forensic toxicology casework using liquid chromatography‐mass spectrometry by Krotulski, Alex J., Papsun, Donna M., Noble, Carolina, Kacinko, Sherri L., Logan, Barry K.

“…New synthetic opioids continue to appear as novel psychoactive substances (NPS) on illicit drug markets. Isotonitazene emerged in mid‐2019, becoming the most…”
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Opioid overdoses involving xylazine in emergency department patients: a multicenter study by Love, Jennifer S., Levine, Michael, Aldy, Kim, Brent, Jeffrey, Krotulski, Alex J., Logan, Barry K., Vargas-Torres, Carmen, Walton, Sara E., Amaducci, Alexandra, Calello, Diane, Hendrickson, Robert, Hughes, Adrienne, Kurt, Anita, Judge, Bryan, Pizon, Anthony, Schwarz, Evan, Shulman, Joshua, Wiegand, Timothy, Wax, Paul, Manini, Alex F.

“…Illicit opioids, consisting largely of fentanyl, novel synthetic opioids, and adulterants, are the primary cause of drug overdose fatality in the United…”
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Pharmacological evaluation and forensic case series of N-pyrrolidino etonitazene (etonitazepyne), a newly emerging 2-benzylbenzimidazole ‘nitazene’ synthetic opioid by Vandeputte, Marthe M., Krotulski, Alex J., Walther, Donna, Glatfelter, Grant C., Papsun, Donna, Walton, Sara E., Logan, Barry K., Baumann, Michael H., Stove, Christophe P.

“…Novel synthetic opioids continue to emerge on recreational drug markets worldwide. In response to legislative bans on fentanyl analogues, non-fentanyl…”
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Reports of Adverse Events Associated with Use of Novel Psychoactive Substances, 2013–2016: A Review by Logan, Barry K., Mohr, Amanda L.A., Friscia, Melissa, Krotulski, Alex J., Papsun, Donna M., Kacinko, Sherri L., Ropero-Miller, Jeri D., Huestis, Marilyn A.

“…Abstract Novel psychoactive substances (NPS) represent significant analytical and interpretive challenges to forensic and clinical toxicologists. Timely access…”
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Plasma pharmacokinetics and pharmacodynamic effects of the 2-benzylbenzimidazole synthetic opioid, isotonitazene, in male rats by Walton, Sara E., Krotulski, Alex J., Glatfelter, Grant C., Walther, Donna, Logan, Barry K., Baumann, Michael H.

“…Rationale Isotonitazene is an illicit synthetic opioid associated with many intoxications and fatalities. Recent studies show that isotonitazene is a potent…”
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Metabolic profile determination of 2F‐viminol – A novel synthetic opioid identified in forensic investigations by Velez, Aracelis, Papsun, Donna M., Scott, Karen S., Krotulski, Alex J.

“…Novel synthetic opioid (NSO) continue to emerge in the United States in the midst of an opioid crisis. The NSO 2F‐viminol was identified in casework at the…”
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Toxicological and pharmacological characterization of novel cinnamylpiperazine synthetic opioids in humans and in vitro including 2-methyl AP-237 and AP-238 by Fogarty, Melissa F., Vandeputte, Marthe M., Krotulski, Alex J., Papsun, Donna, Walton, Sara E., Stove, Christophe P., Logan, Barry K.

“…The recent scheduling actions of fentanyl-related substances in both the United States and China have sparked the emergence and proliferation of other…”
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Eutylone Intoxications—An Emerging Synthetic Stimulant in Forensic Investigations by Krotulski, Alex J, Papsun, Donna M, Chronister, Chris W, Homan, Joseph, Crosby, Michele M, Hoyer, Jennifer, Goldberger, Bruce A, Logan, Barry K

“…Abstract Synthetic stimulants are the largest class of novel psychoactive substances identified each year by forensic laboratories internationally. While…”
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