Search Results - "Kroog, G S"

Expression of Proinflammatory and Proangiogenic Cytokines in Patients with Head and Neck Cancer by ZHONG CHEN, MALHOTRA, P. S, MCCULLAGH, L, MOUSA, S, QUEZADO, M, HERSCHER, L. L, VAN WAES, C, THOMAS, G. R, ONDREY, F. G, DUFFEY, D. C, SMITH, C. W, ENAMORADO, I, YEH, N. T, KROOG, G. S, RUDY, S

“…Altered immune, inflammatory, and angiogenesis responses are observed in patients with head and neck squamous cell carcinoma (HNSCC), and many of these…”
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Mammalian bombesin receptors by Kroog, G S, Jensen, R T, Battey, J F

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Concurrent Paclitaxel and Radiation in the Treatment of Locally Advanced Head and Neck Cancer by SUNWOO, John B, HERSCHER, Laurie L, RUDY, Susan, MUIR, Chris, SUOPING ZHAI, FIGG, William D, COOK, John A, MITCHELL, James B, VAN WAES, Carter, KROOG, Glenn S, THOMAS, Giovana R, ONDREY, Frank G, DUFFEY, Dianne C, SOLOMON, Beth I, BOSS, Carol, ALBERT, Paul S, MCCULLUGH, Linda

“…To determine the feasibility of an organ preservation regimen consisting of infusional paclitaxel administered concurrently with radiotherapy to patients with…”
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Two amino acids in the sixth transmembrane segment of the mouse gastrin-releasing peptide receptor are important for receptor activation by Lin, Y, Jian, X, Lin, Z, Kroog, G S, Mantey, S, Jensen, R T, Battey, J, Northup, J

“…The gastrin-releasing peptide receptor (GRP-R) is a G protein-coupled receptor that mediates a variety of cellular responses, including cell growth and…”
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S189: EARLY, DEEP, AND DURABLE RESPONSES, AND LOW RATES OF CRS WITH REGN5458, A BCMAXCD3 BISPECIFIC ANTIBODY, IN A PHASE 1/2 FIRST-IN-HUMAN STUDY IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA by Zonder, J. A., Richter, J., Bumma, N., Brayer, J., Hoffman, J. E., Bensinger, W. I., Wu, K. L., Xu, L., Chokshi, D., Boyapati, A., Cronier, D., Houvras, Y., Rodriguez Lorenc, K., Kroog, G. S., Dhodapkar, M. V., Lentzsch, S., Cooper, D., Jagannath, S.

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Vasoactive intestinal peptide increases intracellular cAMP and gonadotropin-alpha gene activity in JEG-3 syncytial trophoblasts. Constraints posed by desensitization by DEUTSCH, P. J, YU SUN, KROOG, G. S

“…Expression of the human chorionic gonadotropin (hCG)-alpha gene in placental trophoblasts is markedly stimulated by cAMP, a property preserved in a reporter…”
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Phosphorylation uncouples the gastrin-releasing peptide receptor from G(q) by Kroog, G S, Jian, X, Chen, L, Northup, J K, Battey, J F

“…Previous work on the desensitization of G protein-coupled receptors has focused on the role of arrestin binding following receptor phosphorylation. We have…”
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Effect of gastrin-releasing peptide receptor number on receptor affinity, coupling, degradation, and modulation by Tsuda, T, Kusui, T, Hou, W, Benya, R V, Akeson, M A, Kroog, G S, Battey, J F, Jensen, R T

“…The relationship between receptor number and agonist-induced intracellular responses has been well studied in receptors coupled to adenylate cyclase; however,…”
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An Aspartate Residue at the Extracellular Boundary of TMII and an Arginine Residue in TMVII of the Gastrin-Releasing Peptide Receptor Interact To Facilitate Heterotrimeric G Protein Coupling by Donohue, Patrick J, Sainz, Eduardo, Akeson, Mark, Kroog, Glenn S, Mantey, Samuel A, Battey, James F, Jensen, Robert T, Northup, John K

“…The mammalian bombesin receptor subfamily of G protein-coupled receptors currently consists of the gastrin-releasing peptide receptor (GRP-R), neuromedin B…”
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S189: EARLY, DEEP, AND DURABLE RESPONSES, AND LOW RATES OF CRS WITH REGN5458, A BCMAXCD3 BISPECIFIC ANTIBODY, IN A PHASE 1/2 FIRST‐IN‐HUMAN STUDY IN PATIENTS WITH RELAPSED/REFRACTORY MULTIPLE MYELOMA by Zonder, J. A., Richter, J., Bumma, N., Brayer, J., Hoffman, J. E., Bensinger, W. I., Wu, K. L., Xu, L., Chokshi, D., Boyapati, A., Cronier, D., Houvras, Y., Rodriguez Lorenc, K., Kroog, G. S., Dhodapkar, M. V., Lentzsch, S., Cooper, D., Jagannath, S.

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The Gastrin-releasing Peptide Receptor Is Rapidly Phosphorylated by a Kinase Other Than Protein Kinase C After Exposure to Agonist (∗) by Kroog, Glenn S., Sainz, Eduardo, Worland, Peter J., Akeson, Mark A., Benya, Richard V., Jensen, Robert T., Battey, James F.

“…Several guanine nucleotide-binding protein-coupled receptors are known to be rapidly phosphorylated after agonist exposure. In this study we show that the…”
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Phase I trial of RAD001 (everolimus) plus sunitinib in patients with metastatic renal cell carcinoma by Kroog, G. S., Feldman, D. R., Kondagunta, G. V., Ginsberg, M. S., Fischer, P. M., Trinos, M. J., Patil, S., Ishill, N. M., Motzer, R. J.

“…Abstract only 5037^ Background: RAD001 (everolimus) and sunitinib (SUTENT) both have activity in metastatic renal cell carcinoma (mRCC). Combining RAD001 and…”
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Alterations in receptor expression or agonist concentration change the pathways gastrin-releasing peptide receptor uses to regulate extracellular signal-regulated kinase by Chen, Pei-Wen, Kroog, Glenn S

“…G protein-coupled receptors activate extracellular signal-regulated kinases (ERKs) via different pathways in different cell types. In this study, we…”
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Phase I study of weekly gemcitabine as a radiation sensitizer for unresectable pancreatic cancer by Poggi, Matthew M, Kroog, Glenn S, Russo, Angelo, Muir, Christine, Cook, John, Smith, Judith, Mitchell, James B, Herscher, Laurie L

“…To determine the maximal tolerated dose and dose-limiting toxicities (DLTs) of weekly gemcitabine with concurrent radiotherapy (RT) in patients with…”
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