Search Results - "Kronenberg, Florian"

Human Genetics and the Causal Role of Lipoprotein(a) for Various Diseases by Kronenberg, Florian

“…Lipoprotein(a) [Lp(a)] is a highly atherogenic lipoprotein that is under strong genetic control by the LPA gene locus. Genetic variants including a highly…”
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HDL in CKD-The Devil Is in the Detail by Kronenberg, Florian

“…The picture of HDL cholesterol (HDL-C) as the "good" cholesterol has eroded. This is even more surprising because there exists strong evidence that HDL-C is…”
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Lipoprotein(a) beyond the kringle IV repeat polymorphism: The complexity of genetic variation in the LPA gene by Coassin, Stefan, Kronenberg, Florian

“…High lipoprotein(a) [Lp(a)] concentrations are one of the most important genetically determined risk factors for cardiovascular disease. Lp(a) concentrations…”
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Structure, function, and genetics of lipoprotein (a) by Schmidt, Konrad, Noureen, Asma, Kronenberg, Florian, Utermann, Gerd

“…Lipoprotein (a) [Lp(a)] has attracted the interest of researchers and physicians due to its intriguing properties, including an intragenic multiallelic copy…”
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Emerging risk factors and markers of chronic kidney disease progression by Kronenberg, Florian

“…Chronic kidney disease (CKD) is a common condition and its prevalence is increasing. Prognosis is poor, with many patients experiencing disease progression…”
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HaploGrep 2: mitochondrial haplogroup classification in the era of high-throughput sequencing by Weissensteiner, Hansi, Pacher, Dominic, Kloss-Brandstätter, Anita, Forer, Lukas, Specht, Günther, Bandelt, Hans-Jürgen, Kronenberg, Florian, Salas, Antonio, Schönherr, Sebastian

“…Mitochondrial DNA (mtDNA) profiles can be classified into phylogenetic clusters (haplogroups), which is of great relevance for evolutionary, forensic and…”
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Lipoprotein(a): the revenant by Gencer, Baris, Kronenberg, Florian, Stroes, Erik S, Mach, François

“…In the mid-1990s, the days of lipoprotein(a) [Lp(a)] were numbered and many people would not have placed a bet on this lipid particle making it to the next…”
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Lipoprotein(a) in atherosclerotic cardiovascular disease and aortic stenosis: a European Atherosclerosis Society consensus statement by Kronenberg, Florian, Mora, Samia, Stroes, Erik S G, Ference, Brian A, Arsenault, Benoit J, Berglund, Lars, Dweck, Marc R, Koschinsky, Marlys, Lambert, Gilles, Mach, François, McNeal, Catherine J, Moriarty, Patrick M, Natarajan, Pradeep, Nordestgaard, Børge G, Parhofer, Klaus G, Virani, Salim S, von Eckardstein, Arnold, Watts, Gerald F, Stock, Jane K, Ray, Kausik K, Tokgözoğlu, Lale S, Catapano, Alberico L

“…Abstract This 2022 European Atherosclerosis Society lipoprotein(a) [Lp(a)] consensus statement updates evidence for the role of Lp(a) in atherosclerotic…”
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OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation by Schöpf, Bernd, Weissensteiner, Hansi, Schäfer, Georg, Fazzini, Federica, Charoentong, Pornpimol, Naschberger, Andreas, Rupp, Bernhard, Fendt, Liane, Bukur, Valesca, Giese, Irina, Sorn, Patrick, Sant’Anna-Silva, Ana Carolina, Iglesias-Gonzalez, Javier, Sahin, Ugur, Kronenberg, Florian, Gnaiger, Erich, Klocker, Helmut

“…Rewiring of energy metabolism and adaptation of mitochondria are considered to impact on prostate cancer development and progression. Here, we report on…”
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A genome-wide association meta-analysis on lipoprotein (a) concentrations adjusted for apolipoprotein (a) isoforms[S] by Mack, Salome, Coassin, Stefan, Rueedi, Rico, Yousri, Noha A., Seppälä, Ilkka, Gieger, Christian, Schönherr, Sebastian, Forer, Lukas, Erhart, Gertraud, Marques-Vidal, Pedro, Ried, Janina S., Waeber, Gerard, Bergmann, Sven, Dähnhardt, Doreen, Stöckl, Andrea, Raitakari, Olli T., Kähönen, Mika, Peters, Annette, Meitinger, Thomas, Strauch, Konstantin, Kedenko, Ludmilla, Paulweber, Bernhard, Lehtimäki, Terho, Hunt, Steven C., Vollenweider, Peter, Lamina, Claudia, Kronenberg, Florian

“…High lipoprotein (a) [Lp(a)] concentrations are an independent risk factor for cardiovascular outcomes. Concentrations are strongly influenced by apo(a)…”
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Daring to dream: Targeting lipoprotein(a) as a causal and risk-enhancing factor by Koschinsky, Marlys L., Stroes, Erik S.G., Kronenberg, Florian

“…Lipoprotein(a) [Lp(a)], a distinct lipoprotein class, has become a major focus for cardiovascular research. This review is written in light of the recent…”
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Quantifying Atherogenic Lipoproteins: Current and Future Challenges in the Era of Personalized Medicine and Very Low Concentrations of LDL Cholesterol. A Consensus Statement from EAS and EFLM by Langlois, Michel R, Chapman, M John, Cobbaert, Christa, Mora, Samia, Remaley, Alan T, Ros, Emilio, Watts, Gerald F, Borén, Jan, Baum, Hannsjörg, Bruckert, Eric, Catapano, Alberico, Descamps, Olivier S, von Eckardstein, Arnold, Kamstrup, Pia R, Kolovou, Genovefa, Kronenberg, Florian, Langsted, Anne, Pulkki, Kari, Rifai, Nader, Sypniewska, Grazyna, Wiklund, Olov, Nordestgaard, Børge G

“…The European Atherosclerosis Society-European Federation of Clinical Chemistry and Laboratory Medicine Consensus Panel aims to provide recommendations to…”
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Rare genetic variants affecting urine metabolite levels link population variation to inborn errors of metabolism by Cheng, Yurong, Schlosser, Pascal, Hertel, Johannes, Sekula, Peggy, Oefner, Peter J., Spiekerkoetter, Ute, Mielke, Johanna, Freitag, Daniel F., Schmidts, Miriam, Kronenberg, Florian, Eckardt, Kai-Uwe, Thiele, Ines, Li, Yong, Köttgen, Anna

“…Metabolite levels in urine may provide insights into genetic mechanisms shaping their related pathways. We therefore investigate the cumulative contribution of…”
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HaploGrep: a fast and reliable algorithm for automatic classification of mitochondrial DNA haplogroups by Kloss-Brandstätter, Anita, Pacher, Dominic, Schönherr, Sebastian, Weissensteiner, Hansi, Binna, Robert, Specht, Günther, Kronenberg, Florian

“…An ongoing source of controversy in mitochondrial DNA (mtDNA) research is based on the detection of numerous errors in mtDNA profiles that led to erroneous…”
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Leucocyte telomere length and risk of type 2 diabetes mellitus: new prospective cohort study and literature-based meta-analysis by Willeit, Peter, Raschenberger, Julia, Heydon, Emma E, Tsimikas, Sotirios, Haun, Margot, Mayr, Agnes, Weger, Siegfried, Witztum, Joseph L, Butterworth, Adam S, Willeit, Johann, Kronenberg, Florian, Kiechl, Stefan

“…Short telomeres have been linked to various age-related diseases. We aimed to assess the association of telomere length with incident type 2 diabetes mellitus…”
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Genetic studies of urinary metabolites illuminate mechanisms of detoxification and excretion in humans by Schlosser, Pascal, Li, Yong, Sekula, Peggy, Raffler, Johannes, Grundner-Culemann, Franziska, Pietzner, Maik, Cheng, Yurong, Wuttke, Matthias, Steinbrenner, Inga, Schultheiss, Ulla T., Kotsis, Fruzsina, Kacprowski, Tim, Forer, Lukas, Hausknecht, Birgit, Ekici, Arif B., Nauck, Matthias, Völker, Uwe, Walz, Gerd, Oefner, Peter J., Kronenberg, Florian, Mohney, Robert P., Köttgen, Michael, Suhre, Karsten, Eckardt, Kai-Uwe, Kastenmüller, Gabi, Köttgen, Anna

“…The kidneys integrate information from continuous systemic processes related to the absorption, distribution, metabolism and excretion (ADME) of metabolites…”
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Development and validation of a predictive mortality risk score from a European hemodialysis cohort by Floege, Jürgen, Gillespie, Iain A, Kronenberg, Florian, Anker, Stefan D, Gioni, Ioanna, Richards, Sharon, Pisoni, Ronald L, Robinson, Bruce M, Marcelli, Daniele, Froissart, Marc, Eckardt, Kai-Uwe

“…Although mortality risk scores for chronic hemodialysis (HD) patients should have an important role in clinical decision-making, those currently available have…”
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Differences between human plasma and serum metabolite profiles by Yu, Zhonghao, Kastenmüller, Gabi, He, Ying, Belcredi, Petra, Möller, Gabriele, Prehn, Cornelia, Mendes, Joaquim, Wahl, Simone, Roemisch-Margl, Werner, Ceglarek, Uta, Polonikov, Alexey, Dahmen, Norbert, Prokisch, Holger, Xie, Lu, Li, Yixue, Wichmann, H-Erich, Peters, Annette, Kronenberg, Florian, Suhre, Karsten, Adamski, Jerzy, Illig, Thomas, Wang-Sattler, Rui

“…Human plasma and serum are widely used matrices in clinical and biological studies. However, different collecting procedures and the coagulation cascade…”
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A polygenic and family risk score are both independently associated with risk of type 2 diabetes in a population-based study by Duschek, Elena, Forer, Lukas, Schönherr, Sebastian, Gieger, Christian, Peters, Annette, Kronenberg, Florian, Grallert, Harald, Lamina, Claudia

“…The availability of polygenic scores for type 2 diabetes (T2D) raises the question, whether assessing family history might become redundant. However, family…”
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An in-depth analysis of the mitochondrial phylogenetic landscape of Cambodia by Kloss-Brandstätter, Anita, Summerer, Monika, Horst, David, Horst, Basil, Streiter, Gertraud, Raschenberger, Julia, Kronenberg, Florian, Sanguansermsri, Torpong, Horst, Jürgen, Weissensteiner, Hansi

“…Cambodia harbours a variety of human aboriginal populations that have scarcely been studied in terms of genetic diversity of entire mitochondrial genomes. Here…”
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