Search Results - "Kron, L"

Standardization of Care: Impact of an Enhanced Recovery Protocol on Length of Stay, Complications, and Direct Costs after Colorectal Surgery by Thiele, Robert H., MD, Rea, Kathleen M., MSN, APRN, Turrentine, Florence E., PhD, RN, Friel, Charles M., MD, FACS, Hassinger, Taryn E., MD, Goudreau, Bernadette J., BS, Umapathi, Bindu A., MD, Kron, Irving L., MD, FACS, Sawyer, Robert G., MD, FACS, Hedrick, Traci L., MD, FACS, McMurry, Timothy L., PhD

“…Background Colorectal surgery is associated with considerable morbidity and prolonged length of stay (LOS). Recognizing the need for improvement, we…”
Get full text

Postoperative Atrial Fibrillation Significantly Increases Mortality, Hospital Readmission, and Hospital Costs by LaPar, Damien J., MD, MS, Speir, Alan M., MD, Crosby, Ivan K., MD, Fonner, Edwin, DrPH, Brown, Michael, PA-C, Rich, Jeffrey B., MD, Quader, Mohammed, MD, Kern, John A., MD, Kron, Irving L., MD, Ailawadi, Gorav, MD

“…Background New-onset postoperative atrial fibrillation (POAF) is the most common complication following cardiac surgery. However, the magnitude of POAF on…”
Get full text

One-Year Outcomes After MitraClip for Functional Mitral Regurgitation by Ailawadi, Gorav, Lim, D Scott, Mack, Michael J, Trento, Alfredo, Kar, Saibal, Grayburn, Paul A, Glower, Donald D, Wang, Andrew, Foster, Elyse, Qasim, Atif, Weissman, Neil J, Ellis, Jeffrey, Crosson, Lori, Fan, Frank, Kron, Irving L, Pearson, Paul J, Feldman, Ted

“…BACKGROUND:Secondary mitral regurgitation (SMR) occurs in the absence of organic mitral valve disease and may develop as the left ventricle dilates or remodels…”
Get full text

Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death by Stone, Matthew L, Zhao, Yunge, Robert Smith, J, Weiss, Mark L, Kron, Irving L, Laubach, Victor E, Sharma, Ashish K

“…Lung ischemia-reperfusion (IR) injury after transplantation as well as acute shortage of suitable donor lungs are two critical issues impacting lung transplant…”
Get full text

Predicting recurrent mitral regurgitation after mitral valve repair for severe ischemic mitral regurgitation by Kron, Irving L., MD, Hung, Judy, MD, Overbey, Jessica R., MS, Bouchard, Denis, MD, Gelijns, Annetine C., PhD, Moskowitz, Alan J., MD, Voisine, Pierre, MD, O'Gara, Patrick T., MD, Argenziano, Michael, MD, Michler, Robert E., MD, Gillinov, Marc, MD, Puskas, John D., MD, Gammie, James S., MD, Mack, Michael J., MD, Smith, Peter K., MD, Sai-Sudhakar, Chittoor, MD, Gardner, Timothy J., MD, Ailawadi, Gorav, MD, Zeng, Xin, MD, O'Sullivan, Karen, MPH, Parides, Michael K., PhD, Swayze, Roger, RN, BSN, Thourani, Vinod, MD, Rose, Eric A., MD, Perrault, Louis P., MD, Acker, Michael A., MD

“…Abstract Objectives The Cardiothoracic Surgical Trials Network recently reported no difference in the primary end point of left ventricular end-systolic volume…”
Get full text

Blood Transfusion and Infection After Cardiac Surgery by Horvath, Keith A., MD, Acker, Michael A., MD, Chang, Helena, MS, Bagiella, Emilia, PhD, Smith, Peter K., MD, Iribarne, Alexander, MD, MS, Kron, Irving L., MD, Lackner, Pamela, Argenziano, Michael, MD, Ascheim, Deborah D., MD, Gelijns, Annetine C., PhD, Michler, Robert E., MD, Van Patten, Danielle, Puskas, John D., MD, O'Sullivan, Karen, MPH, Kliniewski, Dorothy, RN, BSN, Jeffries, Neal O., PhD, O'Gara, Patrick T., MD, Moskowitz, Alan J., MD, Blackstone, Eugene H., MD

“…Cardiac surgery is the largest consumer of blood products in medicine; although believed life saving, transfusion carries substantial adverse risks. This study…”
Get full text

Smooth muscle phenotypic modulation is an early event in aortic aneurysms by Ailawadi, Gorav, MD, Moehle, Christopher W., BS, Pei, Hong, MD, Walton, Sandra P., BS, Yang, Zequan, MD, PhD, Kron, Irving L., MD, Lau, Christine L., MD, Owens, Gary K., PhD

“…Objectives Vascular smooth muscle cells can undergo profound changes in phenotype, defined by coordinated repression of smooth muscle cell marker genes and…”
Get full text

Stimulation of the Beta2 Adrenergic Receptor at Reperfusion Limits Myocardial Reperfusion Injury via an Interleukin-10-Dependent Anti-Inflammatory Pathway in the Spleen by Tian, Yikui, Miao, Bin, Charles, Eric J., Wu, Di, Kron, Irving L., French, Brent A., Yang, Zequan

“…Background: In addition to the airway-relaxing effects, β2 adrenergic receptor (β2AR) agonists are also found to have broad anti-inflammatory effects. The…”
Get full text

Improved outcomes and value in staged hybrid extent II thoracoabdominal aortic aneurysm repair by Hawkins, Robert B., MD, MSc, Mehaffey, J. Hunter, MD, MSc, Narahari, Adishesh K., BS, Jain, Amit, MD, Ghanta, Ravi K., MD, Kron, Irving L., MD, Kern, John A., MD, Upchurch, Gilbert R., MD

“…Abstract Objective Complex Crawford extent II thoracoabdominal aortic aneurysms (TAAAs) can be treated in a hybrid manner with proximal thoracic endovascular…”
Get full text

Blood product conservation is associated with improved outcomes and reduced costs after cardiac surgery by LaPar, Damien J., MD, MSc, Crosby, Ivan K., MD, Ailawadi, Gorav, MD, Ad, Niv, MD, Choi, Elmer, MD, Spiess, Bruce D., MD, Rich, Jeffery B., MD, Kasirajan, Vigneshwar, MD, Fonner, Edwin, DrPH, Kron, Irving L., MD, Speir, Alan M., MD

“…Background Efforts to reduce blood product use have the potential to avoid transfusion-related complications and reduce health care costs. The purpose of this…”
Get full text

Plasmacytoid Dendritic Cells Mediate Myocardial Ischemia/Reperfusion Injury by Secreting Type I Interferons by Lai, Lina, Zhang, Aimee, Yang, Boris, Charles, Eric J., Kron, Irving L., Yang, Zequan

“…Background We previously demonstrated that ischemically injured cardiomyocytes release cell‐free DNA and HMGB1 (high mobility group box 1 protein) into…”
Get full text

The spleen contributes importantly to myocardial infarct exacerbation during post-ischemic reperfusion in mice via signaling between cardiac HMGB1 and splenic RAGE by Tian, Yikui, Pan, Dongfeng, Chordia, Mahendra D., French, Brent A., Kron, Irving L., Yang, Zequan

“…The spleen plays a critical role in post-infarct myocardial remodeling. However, the role of the spleen in exacerbating myocardial infarction (MI) during acute…”
Get full text

Minimally invasive aortic valve replacement provides equivalent outcomes at reduced cost compared with conventional aortic valve replacement: A real-world multi-institutional analysis by Ghanta, Ravi K., MD, Lapar, Damien J., MD, MSc, Kern, John A., MD, Kron, Irving L., MD, Speir, Alan M., MD, Fonner, Edwin, DrPH, Quader, Mohammed, MD, Ailawadi, Gorav, MD

“…Abstract Background Several single-center studies have reported excellent outcomes with minimally invasive aortic valve replacement (mini-AVR). Although…”
Get full text

Methylene Blue for Vasoplegic Syndrome After Cardiac Operation: Early Administration Improves Survival by Mehaffey, J. Hunter, MD, Johnston, Lily E., MD, MPH, Hawkins, Robert B., MD, Charles, Eric J., MD, Yarboro, Leora, MD, Kern, John A., MD, Ailawadi, Gorav, MD, Kron, Irving L., MD, Ghanta, Ravi K., MD

“…Background Vasoplegic syndrome, defined by hypotension despite normal or increased cardiac output, is associated with high mortality rate after cardiopulmonary…”
Get full text

Bilateral Internal Mammary Artery Use for Coronary Artery Bypass Grafting Remains Underutilized: A Propensity-Matched Multi-Institution Analysis by LaPar, Damien J., MD, MS, Crosby, Ivan K., MD, Rich, Jeffrey B., MD, Quader, Mohammed A., MD, Speir, Alan M., MD, Kern, John A., MD, Tribble, Curt, MD, Kron, Irving L., MD, Ailawadi, Gorav, MD

“…Background Bilateral internal mammary arterial (BIMA) grafts have repeatedly demonstrated superior outcomes compared with single IMA (SIMA) after coronary…”
Get full text

Meaningful Patient-centered Outcomes 1 Year Following Cardiac Surgery by Charles, Eric J., Mehaffey, J. Hunter, Hawkins, Robert B., Burks, Sandra G., McMurry, Timothy L., Yarboro, Leora T., Kern, John A., Ailawadi, Gorav, Kron, Irving L., Stukenborg, George J., Kozower, Benjamin D.

“…OBJECTIVE:To evaluate meaningful, patient-centered outcomes including alive-at-home status and patient-reported quality of life 1 year after cardiac surgery…”
Get full text

Hospital Variation in Mortality From Cardiac Arrest After Cardiac Surgery: An Opportunity for Improvement? by LaPar, Damien J., MD, MS, Ghanta, Ravi K., MD, Kern, John A., MD, Crosby, Ivan K., MD, Rich, Jeffrey B., MD, Speir, Alan M., MD, Kron, Irving L., MD, Ailawadi, Gorav, MD

“…Background Among all postoperative complications, cardiac arrest after cardiac surgical operations has the greatest association with mortality. However,…”
Get full text

Effect of Cardiac Surgery on One-Year Patient-Reported Outcomes: A Prospective Cohort Study by Charles, Eric J., Mehaffey, J. Hunter, Hawkins, Robert B., Green, China J., Craddock, Ashley, Tyerman, Zachary M., Larson, Nathaniel D., Kron, Irving L., Ailawadi, Gorav, Kozower, Benjamin D.

“…Current cardiac surgery risk algorithms and quality measures focus on perioperative outcomes. However, delivering high-value, patient-centered cardiac care…”
Get full text

Experimental Abdominal Aortic Aneurysm Formation Is Mediated by IL-17 and Attenuated by Mesenchymal Stem Cell Treatment by SHARMA, Ashish K, GUANYI LU, KRON, Irving L, LAUBACH, Victor E, MURPHY, Michael P, AILAWADI, Gorav, UPCHURCH, Gilbert R, JESTER, Andrea, JOHNSTON, William F, YUNGE ZHAO, HAJZUS, Vanessa A, REZA SAADATZADEH, M, GANG SU, BHAMIDIPATI, Castigliano M, MEHTA, Gaurav S

“…Abdominal aortic aneurysm (AAA) formation is characterized by inflammation, smooth muscle activation and matrix degradation. This study tests the hypothesis…”
Get full text

Natural history of coexistent mitral regurgitation after aortic valve replacement by Schubert, Sarah A., MD, Yarboro, Leora T., MD, Madala, Sushma, MD, Ayunipudi, Karnika, MD, Kron, Irving L., MD, Kern, John A., MD, Ailawadi, Gorav, MD, Stukenborg, George J., PhD, Ghanta, Ravi K., MD

“…Abstract Objectives The long-term evolution of coexistent mitral regurgitation (MR) after aortic valve replacement (AVR) for aortic stenosis remains poorly…”
Get full text