Search Results - "Krol, Ilona"

E-cadherin is required for metastasis in multiple models of breast cancer by Padmanaban, Veena, Krol, Ilona, Suhail, Yasir, Szczerba, Barbara M., Aceto, Nicola, Bader, Joel S., Ewald, Andrew J.

“…Metastasis is the major driver of death in patients with cancer. Invasion of surrounding tissues and metastasis have been proposed to initiate following loss…”
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Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding by Gkountela, Sofia, Castro-Giner, Francesc, Szczerba, Barbara Maria, Vetter, Marcus, Landin, Julia, Scherrer, Ramona, Krol, Ilona, Scheidmann, Manuel C., Beisel, Christian, Stirnimann, Christian U., Kurzeder, Christian, Heinzelmann-Schwarz, Viola, Rochlitz, Christoph, Weber, Walter Paul, Aceto, Nicola

“…The ability of circulating tumor cells (CTCs) to form clusters has been linked to increased metastatic potential. Yet biological features and vulnerabilities…”
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Detection of clustered circulating tumour cells in early breast cancer by Krol, Ilona, Schwab, Fabienne D., Carbone, Roberta, Ritter, Mathilde, Picocci, Sabrina, De Marni, Marzia L., Stepien, Grazyna, Franchi, Gian M., Zanardi, Andrea, Rissoglio, Marco D., Covelli, Alfredo, Guidi, Guido, Scarinci, Daniele, Castro-Giner, Francesc, Mazzarella, Luca, Doglioni, Claudio, Borghi, Francesca, Milani, Paolo, Kurzeder, Christian, Weber, Walter P., Aceto, Nicola

“…Circulating tumour cell (CTC) clusters have been proposed to be major players in the metastatic spread of breast cancer, particularly during advanced disease…”
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A novel device for elimination of cancer cells from blood specimens by Weth, Agnes, Krol, Ilona, Priesner, Kurt, Donato, Cinzia, Pirker, Stefan, Wolf, Christoph, Aceto, Nicola, Baumgartner, Werner

“…Circulating tumor cells (CTCs) are derivatives of solid cancerous lesions that detach from the tumor mass and enter the blood circulation. CTCs are considered…”
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Denosumab treatment is associated with the absence of circulating tumor cells in patients with breast cancer by Vetter, Marcus, Landin, Julia, Szczerba, Barbara Maria, Castro-Giner, Francesc, Gkountela, Sofia, Donato, Cinzia, Krol, Ilona, Scherrer, Ramona, Balmelli, Catharina, Malinovska, Alexandra, Zippelius, Alfred, Kurzeder, Christian, Heinzelmann-Schwarz, Viola, Weber, Walter Paul, Rochlitz, Christoph, Aceto, Nicola

“…The presence of circulating tumor cells (CTCs) in patients with breast cancer correlates to a bad prognosis. Yet, CTCs are detectable in only a minority of…”
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MyCTC chip: microfluidic-based drug screen with patient-derived tumour cells from liquid biopsies by Schwab, Fabienne D., Scheidmann, Manuel C., Ozimski, Lauren L., Kling, André, Armbrecht, Lucas, Ryser, Till, Krol, Ilona, Strittmatter, Karin, Nguyen-Sträuli, Bich Doan, Jacob, Francis, Fedier, André, Heinzelmann-Schwarz, Viola, Wicki, Andreas, Dittrich, Petra S., Aceto, Nicola

“…Cancer patients with advanced disease are characterized by intrinsic challenges in predicting drug response patterns, often leading to ineffective treatment…”
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The metastatic spread of breast cancer accelerates during sleep by Diamantopoulou, Zoi, Castro-Giner, Francesc, Schwab, Fabienne Dominique, Foerster, Christiane, Saini, Massimo, Budinjas, Selina, Strittmatter, Karin, Krol, Ilona, Seifert, Bettina, Heinzelmann-Schwarz, Viola, Kurzeder, Christian, Rochlitz, Christoph, Vetter, Marcus, Weber, Walter Paul, Aceto, Nicola

“…The metastatic spread of cancer is achieved by the haematogenous dissemination of circulating tumour cells (CTCs). Generally, however, the temporal dynamics…”
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Neutrophils escort circulating tumour cells to enable cell cycle progression by Szczerba, Barbara Maria, Castro-Giner, Francesc, Vetter, Marcus, Krol, Ilona, Gkountela, Sofia, Landin, Julia, Scheidmann, Manuel C., Donato, Cinzia, Scherrer, Ramona, Singer, Jochen, Beisel, Christian, Kurzeder, Christian, Heinzelmann-Schwarz, Viola, Rochlitz, Christoph, Weber, Walter Paul, Beerenwinkel, Niko, Aceto, Nicola

“…A better understanding of the features that define the interaction between cancer cells and immune cells is important for the development of new cancer…”
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A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture by Krol, Jacek, Krol, Ilona, Alvarez, Claudia Patricia Patino, Fiscella, Michele, Hierlemann, Andreas, Roska, Botond, Filipowicz, Witold

“…Brain regions, such as the cortex and retina, are composed of layers of uniform thickness. The molecular mechanism that controls this uniformity is not well…”
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Detection of circulating tumour cell clusters in human glioblastoma by Krol, Ilona, Castro-Giner, Francesc, Maurer, Martina, Gkountela, Sofia, Szczerba, Barbara Maria, Scherrer, Ramona, Coleman, Niamh, Carreira, Suzanne, Bachmann, Felix, Anderson, Stephanie, Engelhardt, Marc, Lane, Heidi, Evans, Thomas Ronald Jeffry, Plummer, Ruth, Kristeleit, Rebecca, Lopez, Juanita, Aceto, Nicola

“…Human glioblastoma (GBM) is a highly aggressive, invasive and hypervascularised malignant brain cancer. Individual circulating tumour cells (CTCs) are…”
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An In Vivo CRISPR Screen Identifies Stepwise Genetic Dependencies of Metastatic Progression by Scheidmann, Manuel C, Castro-Giner, Francesc, Strittmatter, Karin, Krol, Ilona, Paasinen-Sohns, Aino, Scherrer, Ramona, Donato, Cinzia, Gkountela, Sofia, Szczerba, Barbara M, Diamantopoulou, Zoi, Muenst, Simone, Vlajnic, Tatjana, Kunz, Leo, Vetter, Marcus, Rochlitz, Christoph, Taylor, Verdon, Giachino, Claudio, Schroeder, Timm, Platt, Randall J, Aceto, Nicola

“…Blood-borne metastasis of breast cancer involves a series of tightly regulated sequential steps, including the growth of a primary tumor lesion, intravasation…”
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Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes by Terczyńska-Dyla, Ewa, Bibert, Stephanie, Duong, Francois H. T., Krol, Ilona, Jørgensen, Sanne, Collinet, Emilie, Kutalik, Zoltán, Aubert, Vincent, Cerny, Andreas, Kaiser, Laurent, Malinverni, Raffaele, Mangia, Alessandra, Moradpour, Darius, Müllhaupt, Beat, Negro, Francesco, Santoro, Rosanna, Semela, David, Semmo, Nasser, Heim, Markus H., Bochud, Pierre-Yves, Hartmann, Rune

“…Hepatitis C virus (HCV) infections are the major cause of chronic liver disease, cirrhosis and hepatocellular carcinoma worldwide. Both spontaneous and…”
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IFN-λ receptor 1 expression is induced in chronic hepatitis C and correlates with the IFN-λ3 genotype and with nonresponsiveness to IFN-α therapies by Duong, Francois H T, Trincucci, Gaia, Boldanova, Tujana, Calabrese, Diego, Campana, Benedetta, Krol, Ilona, Durand, Sarah C, Heydmann, Laura, Zeisel, Mirjam B, Baumert, Thomas F, Heim, Markus H

“…The molecular mechanisms that link IFN-λ3 genotypes to differential induction of interferon (IFN)-stimulated genes (ISGs) in the liver of patients with chronic…”
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Pegylated IFN-α regulates hepatic gene expression through transient Jak/STAT activation by Dill, Michael T, Makowska, Zuzanna, Trincucci, Gaia, Gruber, Andreas J, Vogt, Julia E, Filipowicz, Magdalena, Calabrese, Diego, Krol, Ilona, Lau, Daryl T, Terracciano, Luigi, van Nimwegen, Erik, Roth, Volker, Heim, Markus H

“…The use of pegylated interferon-α (pegIFN-α) has replaced unmodified recombinant IFN-α for the treatment of chronic viral hepatitis. While the superior…”
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Abstract PO5-18-04: Effect of Digoxin on clusters of circulating tumor cells in patients with metastatic breast cancer (DICCT) by Vetter, Marcus, Ngyuen-Sträuli, Bich Doan, Krol, Ilona, Ring, Alexander, Kohler, Angela, Castro-Giner, Francesc, Vogel, Maren, Kuhar, Cvetka Grasic, Schwab, Fabienne, Heinzelmann-Schwarz, Viola, Pfister, Gabriela Kuster, Weber, Walter, Kurzeder, Christian, Aceto, Nicola

“…Abstract Background: The presence of circulating tumor cell (CTC) clusters is associated with tumor progression and with a bad prognosis in various cancer…”
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CD44v6 Defines a New Population of Circulating Tumor Cells Not Expressing EpCAM by Belthier, Guillaume, Homayed, Zeinab, Grillet, Fanny, Duperray, Christophe, Vendrell, Julie, Krol, Ilona, Bravo, Sophie, Boyer, Jean-Christophe, Villeronce, Olivia, Vitre-Boubaker, Jihane, Heaug-Wane, Diana, Macari-Fine, Françoise, Smith, Jai, Merlot, Matthieu, Lossaint, Gérald, Mazard, Thibault, Portales, Fabienne, Solassol, Jérôme, Ychou, Marc, Aceto, Nicola, Mamessier, Emilie, Bertucci, François, Pascussi, Jean Marc, Samalin, Emmanuelle, Hollande, Frédéric, Pannequin, Julie

“…Circulating tumor cells (CTCs) are promising diagnostic and prognostic tools for clinical use. In several cancers, including colorectal and breast, the CTC…”
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Hepatic Notch1 deletion predisposes to diabetes and steatosis via glucose-6-phosphatase and perilipin-5 upregulation by Bernsmeier, Christine, Dill, Michael T, Provenzano, Angela, Makowska, Zuzanna, Krol, Ilona, Muscogiuri, Giovanna, Semela, David, Tornillo, Luigi, Marra, Fabio, Heim, Markus H, Duong, François H T

“…Notch signaling pathways have recently been implicated in the pathogenesis of metabolic diseases. However, the role of hepatic Notch signaling in glucose and…”
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Pegylated IFN-[alpha] regulates hepatic gene expression through transient Jak/STAT activation by Dill, Michael T, Makowska, Zuzanna, Trincucci, Gaia, Gruber, Andreas J, Vogt, Julia E, Filipowicz, Magdalena, Calabrese, Diego, Krol, Ilona, Lau, Daryl T, Terracciano, Luigi, van Nimwegen, Erik, Roth, Volker, Heim, Markus H

“…The use of pegylated interferon-α has replaced unmodified recombinant IFN-α for the treatment of chronic viral hepatitis. While the superior antiviral efficacy…”
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Correction: Corrigendum: Reduced IFNλ4 activity is associated with improved HCV clearance and reduced expression of interferon-stimulated genes by Terczyńska-Dyla, Ewa, Bibert, Stephanie, Duong, Francois H. T., Krol, Ilona, Jørgensen, Sanne, Collinet, Emilie, Kutalik, Zoltán, Aubert, Vincent, Cerny, Andreas, Kaiser, Laurent, Malinverni, Raffaele, Mangia, Alessandra, Moradpour, Darius, Müllhaupt, Beat, Negro, Francesco, Santoro, Rosanna, Semela, David, Semmo, Nasser, Heim, Markus H., Bochud, Pierre-Yves, Hartmann, Rune

“…Nature Communications 5: Article number:5699 (2014); Published: 23 December 2014; Updated: 29 June 2015 In this Article, Rune Hartman was omitted as joint…”
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75 by Terczyńska-Dyla, Ewa, Bibert, Stephanie, Duong, Francois H.T., Krol, Ilona, Jørgensen, Sanne, Collinet, Emilie, Kutalik, Zoltán, Aubert, Vincent, Cerny, Andreas, Kaiser, Laurent, Malinverni, Raffaele, Mangia, Alessandra, Moradpour, Darius, Müllhaupt, Beat, Negro, Francesco, Santoro, Rosanna, Semela, David, Semmo, Nasser, Heim, Markus H., Bochud, Pierre-Yves, Hartmann, Rune

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