Search Results - "Krokowski, D"
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Imatinib mesylate in scleroderma-associated diffuse skin fibrosis: a phase II multicentre randomized double-blinded controlled trial
Published in British journal of dermatology (1951) (01-11-2012)“…Summary Background Imatinib mesylate is a potent inhibitor of platelet‐derived growth factor and transforming growth factor‐β signalling pathways which may…”
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Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics
Published in Communications biology (30-10-2020)“…Alveolar epithelial type II (AETII) cells are important for lung epithelium maintenance and function. We demonstrate that AETII cells from mouse lungs exposed…”
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A Unique ISR Program Determines Cellular Responses to Chronic Stress
Published in Molecular cell (07-12-2017)“…The integrated stress response (ISR) is a homeostatic mechanism induced by endoplasmic reticulum (ER) stress. In acute/transient ER stress, decreased global…”
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Stress-induced perturbations in intracellular amino acids reprogram mRNA translation in osmoadaptation independently of the ISR
Published in Cell reports (Cambridge) (19-07-2022)“…The integrated stress response (ISR) plays a pivotal role in adaptation of translation machinery to cellular stress. Here, we demonstrate an ISR-independent…”
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C107 MITOCHONDRIA AND METABOLIC ALTERATIONS IN LUNG DISEASE: Role Of Mitochondrial Micrornas In Alveolar Epithelial Type Ii Cells Response To Cigarette Smoke
Published in American journal of respiratory and critical care medicine (01-01-2017)“…Rationale: The effect of Cigarette Smoke on type II alveolar epithelial (ATII) is of significant interest because of the central role of ATII in maintaining…”
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Yeast ribosomal P0 protein has two separate binding sites for P1/P2 proteins
Published in Molecular microbiology (01-04-2006)“…Summary The ribosome has a distinct lateral protuberance called the stalk; in eukaryotes it is formed by the acidic ribosomal P‐proteins which are organized as…”
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Structural Characterization of the Ribosomal P1A−P2B Protein Dimer by Small-Angle X-ray Scattering and NMR Spectroscopy
Published in Biochemistry (Easton) (20-02-2007)“…The five ribosomal P-proteins, denoted P0-(P1−P2)2, constitute the stalk structure of the large subunit of eukaryotic ribosomes. In the yeast Saccharomyces…”
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Elevated copy number of L-A virus in yeast mutant strains defective in ribosomal stalk
Published in Biochemical and biophysical research communications (06-04-2007)“…The eukaryotic ribosomal stalk, composed of the P-proteins, is a part of the GTPase-associated-center which is directly responsible for stimulation of…”
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Structural Characterization of Yeast Acidic Ribosomal P Proteins Forming the P1A−P2B Heterocomplex
Published in Biochemistry (Easton) (01-04-2003)“…Acidic ribosomal P proteins form a distinct lateral protuberance on the 60S ribosomal subunit. In yeast, this structure is composed of two heterocomplexes…”
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Overexpression, purification and characterization of the acidic ribosomal P-proteins from Candida albicans
Published in Biochimica et biophysica acta (11-06-2004)“…In all eukaryotic cells, acidic ribosomal P-proteins form a lateral protuberance on the 60S ribosomal subunit—the so-called stalk—structure that plays an…”
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Cloning and characterization of the gene encoding ribosomal P0 phosphoprotein from Neurospora crassa
Published in Acta biochimica polonica (01-01-2002)“…A gene for ribosomal protein P0 that belongs to the family of ribosomal P proteins was isolated from a Neurospora crassa cDNA library, using polyclonal…”
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Pulmonary Lymphangioma
Published in The Annals of thoracic surgery (2008)“…We report on the very rare case of a 49-year-old man with a large solitary pulmonary lymphangioma. Rapid growth of the tumor led to dyspnea and pain. A chest…”
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