Search Results - "Kroeze, Hans"

Malaria parasite evades mosquito immunity by glutaminyl cyclase-mediated posttranslational protein modification by Kolli, Surendra Kumar, Molina-Cruz, Alvaro, Araki, Tamasa, Geurten, Fiona J A, Ramesar, Jai, Chevalley-Maurel, Severine, Kroeze, Hans J, Bezemer, Sascha, de Korne, Clarize, Withers, Roxanne, Raytselis, Nadia, El Hebieshy, Angela F, Kim, Robbert Q, Child, Matthew A, Kakuta, Soichiro, Hisaeda, Hajime, Kobayashi, Hirotaka, Annoura, Takeshi, Hensbergen, Paul J, Franke-Fayard, Blandine M, Barillas-Mury, Carolina, Scheeren, Ferenc A, Janse, Chris J

“…Glutaminyl cyclase (QC) modifies N-terminal glutamine or glutamic acid residues of target proteins into cyclic pyroglutamic acid (pGlu). Here, we report the…”
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The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission by Marin-Mogollon, Catherin, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, van Pul, Fiona J. A., Ramesar, Jai, Othman, Ahmad Syibli, Kroeze, Hans, Miao, Jun, Cui, Liwang, Williamson, Kim C., Sauerwein, Robert W., Janse, Chris J., Khan, Shahid M.

“…Two members of 6-cysteine (6-cys) protein family, P48/45 and P230, are important for gamete fertility in rodent and human malaria parasites and are leading…”
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Replication of Plasmodium in reticulocytes can occur without hemozoin formation, resulting in chloroquine resistance by Lin, Jing-Wen, Spaccapelo, Roberta, Schwarzer, Evelin, Sajid, Mohammed, Annoura, Takeshi, Deroost, Katrien, Ravelli, Raimond B G, Aime, Elena, Capuccini, Barbara, Mommaas-Kienhuis, Anna M, O'Toole, Tom, Prins, Frans, Franke-Fayard, Blandine M D, Ramesar, Jai, Chevalley-Maurel, Séverine, Kroeze, Hans, Koster, Abraham J, Tanke, Hans J, Crisanti, Andrea, Langhorne, Jean, Arese, Paolo, Van den Steen, Philippe E, Janse, Chris J, Khan, Shahid M

“…Most studies on malaria-parasite digestion of hemoglobin (Hb) have been performed using P. falciparum maintained in mature erythrocytes, in vitro. In this…”
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Three members of the 6-cys protein family of Plasmodium play a role in gamete fertility by van Dijk, Melissa R, van Schaijk, Ben C L, Khan, Shahid M, van Dooren, Maaike W, Ramesar, Jai, Kaczanowski, Szymon, van Gemert, Geert-Jan, Kroeze, Hans, Stunnenberg, Hendrik G, Eling, Wijnand M, Sauerwein, Robert W, Waters, Andrew P, Janse, Chris J

“…The process of fertilization is critically dependent on the mutual recognition of gametes and in Plasmodium, the male gamete surface protein P48/45 is vital to…”
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Screening of viral-vectored P. falciparum pre-erythrocytic candidate vaccine antigens using chimeric rodent parasites by Kolli, Surendra Kumar, Salman, Ahmed M, Ramesar, Jai, Chevalley-Maurel, Severine, Kroeze, Hans, Geurten, Fiona G A, Miyazaki, Shinya, Mukhopadhyay, Ekta, Marin-Mogollon, Catherin, Franke-Fayard, Blandine, Hill, Adrian V S, Janse, Chris J

“…To screen for additional vaccine candidate antigens of Plasmodium pre-erythrocytic stages, fourteen P. falciparum proteins were selected based on expression in…”
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Rapid Generation of Marker-Free P. falciparum Fluorescent Reporter Lines Using Modified CRISPR/Cas9 Constructs and Selection Protocol by Mogollon, Catherin Marin, van Pul, Fiona J A, Imai, Takashi, Ramesar, Jai, Chevalley-Maurel, Séverine, de Roo, Guido M, Veld, Sabrina A J, Kroeze, Hans, Franke-Fayard, Blandine M D, Janse, Chris J, Khan, Shahid M

“…The CRISPR/Cas9 system is a powerful genome editing technique employed in a wide variety of organisms including recently the human malaria parasite, P…”
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Proteomic profiling of Plasmodium sporozoite maturation identifies new proteins essential for parasite development and infectivity by Lasonder, Edwin, Janse, Chris J, van Gemert, Geert-Jan, Mair, Gunnar R, Vermunt, Adriaan M W, Douradinha, Bruno G, van Noort, Vera, Huynen, Martijn A, Luty, Adrian J F, Kroeze, Hans, Khan, Shahid M, Sauerwein, Robert W, Waters, Andrew P, Mann, Matthias, Stunnenberg, Hendrik G

“…Plasmodium falciparum sporozoites that develop and mature inside an Anopheles mosquito initiate a malaria infection in humans. Here we report the first…”
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Creation and preclinical evaluation of genetically attenuated malaria parasites arresting growth late in the liver by Franke-Fayard, Blandine, Marin-Mogollon, Catherin, Geurten, Fiona J. A., Chevalley-Maurel, Séverine, Ramesar, Jai, Kroeze, Hans, Baalbergen, Els, Wessels, Els, Baron, Ludivine, Soulard, Valérie, Martinson, Thomas, Aleshnick, Maya, Huijs, Antonius T. G., Subudhi, Amit K., Miyazaki, Yukiko, Othman, Ahmad Syibli, Kolli, Surendra Kumar, Lamers, Olivia A. C., Roques, Magali, Stanway, Rebecca R., Murphy, Sean C., Foquet, Lander, Moita, Diana, Mendes, António M., Prudêncio, Miguel, Dechering, Koen J., Heussler, Volker T., Pain, Arnab, Wilder, Brandon K., Roestenberg, Meta, Janse, Chris J.

“…Whole-sporozoite (WSp) malaria vaccines induce protective immune responses in animal malaria models and in humans. A recent clinical trial with a WSp vaccine…”
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Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites by Marin-Mogollon, Catherin, van Pul, Fiona J A, Miyazaki, Shinya, Imai, Takashi, Ramesar, Jai, Salman, Ahmed M, Winkel, Beatrice M F, Othman, Ahmad Syibli, Kroeze, Hans, Chevalley-Maurel, Severine, Reyes-Sandoval, Arturo, Roestenberg, Meta, Franke-Fayard, Blandine, Janse, Chris J, Khan, Shahid M

“…Rodent malaria parasites where the gene encoding circumsporozoite protein (CSP) has been replaced with csp genes from the human malaria parasites, Plasmodium…”
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Generation of a genetically modified chimeric plasmodium falciparum parasite expressing plasmodium vivax circumsporozoite protein for malaria vaccine development by Miyazaki, Yukiko, Marin-Mogollon, Catherin, Imai, Takashi, M. Mendes, António, van der Laak, Rianne, Sturm, Angelika, Geurten, Fiona J. A., Miyazaki, Shinya, Chevalley-Maurel, Severine, Ramesar, Jai, Kolli, Surendra K., Kroeze, Hans, van Schuijlenburg, Roos, Salman, Ahmed M., Wilder, Brandon K., Reyes-Sandoval, Arturo, Dechering, Koen J., Prudêncio, Miguel, Janse, Chris J., Khan, Shahid M., Franke-Fayard, Blandine

“…Copyright © 2020 Miyazaki, Marin-Mogollon, Imai, Mendes, van der Laak, Sturm, Geurten, Miyazaki, Chevalley-Maurel, Ramesar, Kolli, Kroeze, van Schuijlenburg,…”
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A versatile Plasmodium falciparum reporter line expressing NanoLuc enables highly sensitive multi-stage drug assays by Miyazaki, Yukiko, Vos, Martijn W., Geurten, Fiona J. A., Bigeard, Pierre, Kroeze, Hans, Yoshioka, Shohei, Arisawa, Mitsuhiro, Inaoka, Daniel Ken, Soulard, Valerie, Dechering, Koen J., Franke-Fayard, Blandine, Miyazaki, Shinya

“…Transgenic luciferase-expressing Plasmodium falciparum parasites have been widely used for the evaluation of anti-malarial compounds. Here, to screen for…”
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A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages by Marin-Mogollon, Catherin, Salman, Ahmed M, Koolen, Karin M J, Bolscher, Judith M, van Pul, Fiona J A, Miyazaki, Shinya, Imai, Takashi, Othman, Ahmad Syibli, Ramesar, Jai, van Gemert, Geert-Jan, Kroeze, Hans, Chevalley-Maurel, Severine, Franke-Fayard, Blandine, Sauerwein, Robert W, Hill, Adrian V S, Dechering, Koen J, Janse, Chris J, Khan, Shahid M

“…Transgenic malaria parasites expressing fluorescent and bioluminescent proteins are valuable tools to interrogate malaria-parasite biology and to evaluate…”
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Combinatorial Tim‐3 and PD‐1 activity sustains antigen‐specific Th1 cell numbers during blood‐stage malaria by Dookie, Rebecca S., Villegas‐Mendez, Ana, Kroeze, Hans, Barrett, Jordan R., Draper, Simon J., Franke‐Fayard, Blandine M., Janse, Chris J., MacDonald, Andrew S., Couper, Kevin N.

“…Aims Co‐inhibitory receptors play a major role in controlling the Th1 response during blood‐stage malaria. Whilst PD‐1 is viewed as the dominant co‐inhibitory…”
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Egress of Plasmodium berghei gametes from their host erythrocyte is mediated by the MDV-1/PEG3 protein by Ponzi, Marta, Sidén-Kiamos, Inga, Bertuccini, Lucia, Currà, Chiara, Kroeze, Hans, Camarda, Grazia, Pace, Tomasino, Franke-Fayard, Blandine, Laurentino, Eliane C, Louis, Christos, Waters, Andrew P, Janse, Chris J, Alano, Pietro

“…Malaria parasites invade erythrocytes of their host both for asexual multiplication and for differentiation to male and female gametocytes - the precursor…”
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Expression of full-length Plasmodium falciparum P48/45 in P. berghei blood stages: A method to express and evaluate vaccine antigens by Othman, Ahmad Syibli, Lin, Jing-wen, Franke-Fayard, Blandine M., Kroeze, Hans, van Pul, Fiona J.A., Chevalley-Maurel, Séverine, Ramesar, Jai, Marin-Mogollon, Catherin, Jore, Matthijs M., Morin, Merribeth J., Long, Carole A., Sauerwein, Robert, Birkett, Ashley, Miura, Kazutoyo, Janse, Chris J., Khan, Shahid M.

“…•Full-length Pfs48/45 protein is efficiently expressed in blood stages of P. berghei.•P. berghei blood-stage expressed Pfs48/45 retain conformational…”
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A genotype and phenotype database of genetically modified malaria-parasites by Janse, Chris J, Kroeze, Hans, van Wigcheren, Auke, Mededovic, Senad, Fonager, Jannik, Franke-Fayard, Blandine, Waters, Andrew P, Khan, Shahid M

“…The RMgm database, www.pberghei.eu , is a web-based, manually curated, repository containing information on genetically modified rodent-malaria parasites. It…”
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Author Correction: The Plasmodium falciparum male gametocyte protein P230p, a paralog of P230, is vital for ookinete formation and mosquito transmission by Marin-Mogollon, Catherin, van de Vegte-Bolmer, Marga, van Gemert, Geert-Jan, van Pul, Fiona J. A., Ramesar, Jai, Othman, Ahmad Syibli, Kroeze, Hans, Miao, Jun, Cui, Liwang, Williamson, Kim C., Sauerwein, Robert W., Janse, Chris J., Khan, Shahid M.

“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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Plasmodium TRAP/MIC2 family member, TRAP-Like Protein (TLP), is involved in tissue traversal by sporozoites by Moreira, Cristina K, Templeton, Thomas J, Lavazec, Catherine, Hayward, Rhian E, Hobbs, Charlotte V, Kroeze, Hans, Janse, Chris J, Waters, Andrew P, Sinnis, Photini, Coppi, Alida

“…In the apicomplexan protozoans motility and cell invasion are mediated by the TRAP/MIC2 family of transmembrane proteins, members of which link extracellular…”
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The subcellular location of ovalbumin in Plasmodium berghei blood stages influences the magnitude of T-cell responses by Lin, Jing-Wen, Shaw, Tovah N, Annoura, Takeshi, Fougère, Aurélie, Bouchier, Pascale, Chevalley-Maurel, Séverine, Kroeze, Hans, Franke-Fayard, Blandine, Janse, Chris J, Couper, Kevin N, Khan, Shahid M

“…Model antigens are frequently introduced into pathogens to study determinants that influence T-cell responses to infections. To address whether an antigen's…”
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Experimentally controlled downregulation of the histone chaperone FACT in Plasmodium berghei reveals that it is critical to male gamete fertility by Laurentino, Eliane C., Taylor, Sonya, Mair, Gunnar R., Lasonder, Edwin, Bartfai, Richard, Stunnenberg, Hendrik G., Kroeze, Hans, Ramesar, Jai, Franke‐Fayard, Blandine, Khan, Shahid M., Janse, Chris J., Waters, Andrew P.

“…Summary Human FACT (facilitates chromatin transcription) consists of the proteins SPT16 and SSRP1 and acts as a histone chaperone in the (dis)assembly of…”
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