Search Results - "Kroetz, Danielle"

Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection by Kroetz, Danielle N, Allen, Ronald M, Schaller, Matthew A, Cavallaro, Cleyton, Ito, Toshihiro, Kunkel, Steven L

“…Influenza A virus (IAV) is an airborne pathogen that causes significant morbidity and mortality each year. Macrophages (Mϕ) are the first immune population to…”
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The role of cytokines and chemokines in Histoplasma capsulatum infection by Kroetz, Danielle N., Deepe, George S.

“…► The involvement of Th1 and Th17 cytokines in mediating a protective immune response to Histoplasma capsulatum. ► How cytokines such as IL-4 and IL-10 dampen…”
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CCR5 dictates the equilibrium of proinflammatory IL-17+ and regulatory Foxp3+ T cells in fungal infection by Kroetz, Danielle N, Deepe, Jr, George S

“…CCR5 is a chemotactic mediator for inflammatory cells as well as regulatory T cells (Tregs). In this study, we investigated the role of CCR5 during infection…”
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An aberrant thymus in CCR5-/- mice is coupled with an enhanced adaptive immune response in fungal infection by Kroetz, Danielle N, Deepe, Jr, George S

“…CCR5 is a potent mediator of regulatory T cell (Treg) chemotaxis. In murine histoplasmosis, mice lacking CCR5 or endogenous CCL4 have a reduced number of Tregs…”
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CCR5 Deficiency Mitigates the Deleterious Effects of Tumor Necrosis Factor α Antagonism in Murine Histoplasmosis by Kroetz, Danielle N., Deepe, George S.

“…In murine histoplasmosis, tumor necrosis factor α (TNF-α) antagonism increases the number of regulatory T cells (Tregs) in lungs, and these cells profoundly…”
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Type I Interferon Induced Epigenetic Regulation of Macrophages Suppresses Innate and Adaptive Immunity in Acute Respiratory Viral Infection: e1005338 by Kroetz, Danielle N, Allen, Ronald M, Schaller, Matthew A, Cavallaro, Cleyton, Ito, Toshihiro, Kunkel, Steven L

“…Influenza A virus (IAV) is an airborne pathogen that causes significant morbidity and mortality each year. Macrophages (M[varphi]) are the first immune…”
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Histone methyltransferase, Setdb2, regulates wound healing in a diet-induced obesity model of diabetes (IRM9P.601) by Joshi, Amrita, Allen, Ronald, Kroetz, Danielle, Schaller, Matthew, Dalton, Jennifer, Kunkel, Steven, Gallagher, Katherine

“…Abstract Impaired wound healing in Type 2 diabetes (T2D) is associated with a chronic inflammatory response mediated by accumulation of macrophages producing…”
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Epigenetic regulation of IL‐12‐dependent T cell proliferation by Schaller, Matthew, Ito, Toshihiro, Allen, Ronald M., Kroetz, Danielle, Kittan, Nicolai, Ptaschinski, Catherine, Cavassani, Karen, Carson, William F., Godessart, Nuria, Grembecka, Jolanta, Cierpicki, Tomasz, Dou, Yali, Kunkel, Steven L.

“…Mll1, regulated by IL‐12 in CD4+ T cells, enhances the proliferation of the Th1 response. It is well established that the cytokine IL‐12 and the transcription…”
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Regulation of CD4+ T cell activation and effector function by the histone acetyltransferase Myst1 (IRM6P.662) by Carson, William, Mertz, David, Cavassani, Karen, Mukherjee, Sumanta, Harissa, Batoul, Kroetz, Danielle, Schaller, Matthew, Dou, Yali, Kunkel, Steven

“…Abstract Chromatin remodeling events are central molecular mechanisms that serve to govern CD4+ T cell function through regulation of gene accessibility. Myst1…”
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Response to Comment on “CCR5 Dictates the Equilibrium of Proinflammatory IL-17+ and Regulatory Foxp3+ T Cells in Fungal Infections” by Kroetz, Danielle N., Deepe, George S.

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Type II cytokines impair host defense against an intracellular fungal pathogen by amplifying macrophage generation of IL-33 by Verma, A, Kroetz, D N, Tweedle, J L, Deepe, G S

“…Interleukin (IL)-4 subverts protective immunity to multiple intracellular pathogens, including the fungus Histoplasma capsulatum . Previously, we reported that…”
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The role of CCR5 in protection against Histoplasma capsulatum infection by Kroetz, Danielle N

“…Histoplasma capsulatum is a dimorphic fungus that is found worldwide, but is endemic in the Midwest and Southeast regions of the United States. Infection with…”
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