Search Results - "Kroese, Frans G.M."

The value of rituximab treatment in primary Sjögren's syndrome by Verstappen, Gwenny M, van Nimwegen, Jolien F, Vissink, Arjan, Kroese, Frans G.M, Bootsma, Hendrika

“…Abstract The rationale for B-cell depletion therapy with rituximab in pSS relies upon the well-established role of B-cell hyperactivity in immunopathogenesis…”
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Autoimmunity: Break-through in the diagnosis and treatment of immune-mediated inflammatory diseases by Kroese, Frans G.M, Baeten, Dominique, Huizinga, Tom W.J

“…Abstract The study of fundamental mechanisms of autoimmunity has been instrumental to clinical progress in the diagnosis and treatment of a range of…”
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Biotribological properties of xerostomia patient saliva and its enhancement by Sharma, Prashant K., Vinke, Jeroen, Oude Elberink, Marijn, Stokman, Monique A., Kroese, Frans G.M., Nazmi, Kamran, Bikker, Floris J., van der Mei, Henny C., Vissink, Arjan

“…The study aimed to quantify the lubricating properties of chewing stimulated whole saliva from healthy controls (n=22), from patients suffering from primary…”
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Th17 cells in primary Sjögren's syndrome: Pathogenicity and plasticity by Verstappen, Gwenny M., Corneth, Odilia B.J., Bootsma, Hendrika, Kroese, Frans G.M.

“…Th17 cells play an important physiological role at mucosal barriers, and are involved in inflammatory responses to pathogens. Th17 cells and their signature…”
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Shared gut, but distinct oral microbiota composition in primary Sjögren's syndrome and systemic lupus erythematosus by van der Meulen, Taco A., Harmsen, Hermie J.M., Vila, Arnau Vich, Kurilshikov, Alexander, Liefers, Silvia C., Zhernakova, Alexandra, Fu, Jingyuan, Wijmenga, Cisca, Weersma, Rinse K., de Leeuw, Karina, Bootsma, Hendrika, Spijkervet, Fred K.L., Vissink, Arjan, Kroese, Frans G.M.

“…Alterations in the microbiota composition of the gastro-intestinal tract are suspected to be involved in the etiopathogenesis of two closely related systemic…”
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FcRL4+ B-cells in salivary glands of primary Sjögren's syndrome patients by Haacke, Erlin A, Bootsma, Hendrika, Spijkervet, Fred K.L, Visser, Annie, Vissink, Arjan, Kluin, Philip M, Kroese, Frans G.M

“…Abstract Fc receptor-like protein 4 (FcRL4) is normally expressed on a small subset of mucosa-associated B-cells, as well as on mucosa-associated lymphoid…”
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B Cell Depletion Therapy Normalizes Circulating Follicular Th Cells in Primary Sjögren Syndrome by Verstappen, Gwenny M, Kroese, Frans G M, Meiners, Petra M, Corneth, Odilia B, Huitema, Minke G, Haacke, Erlin A, van der Vegt, Bert, Arends, Suzanne, Vissink, Arjan, Bootsma, Hendrika, Abdulahad, Wayel H

“…To assess the effect of B cell depletion therapy on effector CD4+ T cell homeostasis and its relation to objective measures of disease activity in patients…”
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Long Noncoding RNA Expression Profiling in Normal B-Cell Subsets and Hodgkin Lymphoma Reveals Hodgkin and Reed-Sternberg Cell–Specific Long Noncoding RNAs by Tayari, Masoumeh, Winkle, Melanie, Kortman, Gertrud, Sietzema, Jantine, de Jong, Debora, Terpstra, Martijn, Mestdagh, Pieter, Kroese, Frans G.M, Visser, Lydia, Diepstra, Arjan, Kok, Klaas, van den Berg, Anke, Kluiver, Joost

“…Hodgkin lymphoma (HL) is a malignancy of germinal center (GC) B-cell origin. To explore the role of long noncoding RNAs (lncRNAs) in HL, we studied lncRNA…”
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Imaging in Primary Sjögren's Syndrome by van Ginkel, Martha S, Glaudemans, Andor W J M, van der Vegt, Bert, Mossel, Esther, Kroese, Frans G M, Bootsma, Hendrika, Vissink, Arjan

“…Primary Sjögren's syndrome (pSS) is a systemic autoimmune disease characterized by dysfunction and lymphocytic infiltration of the salivary and lacrimal…”
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Parotid Gland Biopsy, the Alternative Way to Diagnose Sjögren Syndrome by Spijkervet, Fred K.L., DMD, PhD, Haacke, Erlin, MD, Kroese, Frans G.M., PhD, Bootsma, Hendrika, MD, PhD, Vissink, Arjan, DMD, MD, PhD

“…Salivary gland biopsy is a technique broadly applied for the diagnosis of Sjögren syndrome (SS), lymphoma in SS, and connective tissue disorders (sarcoidosis,…”
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Viral infections as potential triggers of type 1 diabetes by van der Werf, Nienke, Kroese, Frans G.M., Rozing, Jan, Hillebrands, Jan-Luuk

“…During the last decades, the incidence of type 1 diabetes (T1D) has increased significantly, reaching percentages of 3% annually worldwide. This increase…”
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Low body temperature governs the decline of circulating lymphocytes during hibernation through sphingosine-1-phosphate by Bouma, Hjalmar R, Kroese, Frans G.M, Kok, Jan Willem, Talaei, Fatimeh, Boerema, Ate S, Herwig, Annika, Draghiciu, Oana, van Buiten, Azuwerus, Epema, Anne H, van Dam, Annie, Strijkstra, Arjen M, Henning, Robert H

“…Hibernation is an energy-conserving behavior consisting of periods of inhibited metabolism ('torpor') with lowered body temperature. Torpor bouts are…”
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Immune regulation and B-cell depletion therapy in patients with primary Sjögren’s syndrome by Abdulahad, Wayel H, Kroese, Frans G.M, Vissink, Arjan, Bootsma, Hendrika

“…Abstract Primary Sjögren’s syndrome (pSS) is an autoimmune exocrinopathy characterized by chronic inflammation and destruction of the salivary and lacrimal…”
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Hibernation is associated with depression of T-cell independent humoral immune responses in the 13-lined ground squirrel by Bouma, Hjalmar R., Henning, Robert H., Kroese, Frans G.M., Carey, Hannah V.

“…► The capacity to induce a humoral response to a TD antigen is maintained throughout hibernation. ► Immunization with a TI-2 antigen does not induce a humoral…”
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How to assess treatment efficacy in Sjögrenʼs syndrome? by Vissink, Arjan, Bootsma, Hendrika, Kroese, Frans G.M, Kallenberg, Cees G.M

“…PURPOSE OF REVIEWThis article critically reviews the current views and discusses the future challenges with regard to assessing disease progression and disease…”
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T cells in primary Sjögren’s syndrome: targets for early intervention by Verstappen, Gwenny M, Kroese, Frans G. M, Bootsma, Hendrika

“…Abstract A histologic hallmark of primary SS (pSS) is lymphocytic infiltration of the salivary and lacrimal glands, in particular by CD4+ T and B cells. In the…”
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Epithelial–immune cell interplay in primary Sjögren syndrome salivary gland pathogenesis by Verstappen, Gwenny M., Pringle, Sarah, Bootsma, Hendrika, Kroese, Frans G. M.

“…In primary Sjögren syndrome (pSS), the function of the salivary glands is often considerably reduced. Multiple innate immune pathways are likely dysregulated…”
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Attenuation of Follicular Helper T Cell–Dependent B Cell Hyperactivity by Abatacept Treatment in Primary Sjögren's Syndrome by Verstappen, Gwenny M., Meiners, Petra M., Corneth, Odilia B. J., Visser, Annie, Arends, Suzanne, Abdulahad, Wayel H., Hendriks, Rudi W., Vissink, Arjan, Kroese, Frans G. M., Bootsma, Hendrika

“…Objective To assess the effect of abatacept (CTLA‐4Ig), which limits T cell activation, on homeostasis of CD4+ T cell subsets and T cell–dependent B cell…”
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Ultrasonography of major salivary glands compared with parotid and labial gland biopsy and classification criteria in patients with clinically suspected primary Sjögren's syndrome by Mossel, Esther, Delli, Konstantina, van Nimwegen, Jolien F, Stel, Alja J, Kroese, Frans G M, Spijkervet, Fred K L, Vissink, Arjan, Arends, Suzanne, Bootsma, Hendrika

“…To assess the validity of ultrasound of major salivary glands (sUS) compared with parotid and labial gland biopsies, sialometry, anti-SSA/Ro antibody status…”
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Germinal centres in diagnostic labial gland biopsies of patients with primary Sjögren's syndrome are not predictive for parotid MALT lymphoma development by Haacke, Erlin A, van der Vegt, Bert, Vissink, Arjan, Spijkervet, Fred K L, Bootsma, Hendrika, Kroese, Frans G M

“…Patients with primary Sjögren's syndrome (pSS) have an increased risk of developing non-Hodgkin's lymphoma (NHL), particularly parotid gland mucosa-associated…”
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