Search Results - "Kröhler, Tarek"

First Small-Molecule Inhibitors Targeting the RNA-Binding Protein IGF2BP2/IMP2 for Cancer Therapy by Dahlem, Charlotte, Abuhaliema, Ali, Kessler, Sonja M, Kröhler, Tarek, Zoller, Ben G. E, Chanda, Shilpee, Wu, Yingwen, Both, Simon, Müller, Fabian, Lepikhov, Konstantin, Kirsch, Susanne H, Laggai, Stephan, Müller, Rolf, Empting, Martin, Kiemer, Alexandra K

“…The RNA-binding protein IGF2BP2/IMP2/VICKZ2/p62 is overexpressed in several tumor entities, promotes tumorigenesis and tumor progression, and has been…”
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A combined computational and functional approach identifies IGF2BP2 as a driver of chemoresistance in a wide array of pre-clinical models of colorectal cancer by Kendzia, Sandra, Franke, Susanne, Kröhler, Tarek, Golob-Schwarzl, Nicole, Schweiger, Caroline, Toeglhofer, Anna M, Skofler, Christina, Uranitsch, Stefan, El-Heliebi, Amin, Fuchs, Julia, Punschart, Andreas, Stiegler, Philipp, Keil, Marlen, Hoffmann, Jens, Henderson, David, Lehrach, Hans, Yaspo, Marie-Laure, Reinhard, Christoph, Schäfer, Reinhold, Keilholz, Ulrich, Regenbrecht, Christian, Schicho, Rudolf, Fickert, Peter, Lax, Sigurd F, Erdmann, Frank, Schulz, Marcel H, Kiemer, Alexandra K, Haybaeck, Johannes, Kessler, Sonja M

“…Chemoresistance is a major cause of treatment failure in colorectal cancer (CRC) therapy. In this study, the impact of the IGF2BP family of RNA-binding…”
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The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma by Kröhler, Tarek, Kessler, Sonja M, Hosseini, Kevan, List, Markus, Barghash, Ahmad, Patial, Sonika, Laggai, Stephan, Gemperlein, Katja, Haybaeck, Johannes, Müller, Rolf, Helms, Volkhard, Schulz, Marcel H, Hoppstädter, Jessica, Blackshear, Perry J, Kiemer, Alexandra K

“…Hepatic lipid deposition and inflammation represent risk factors for hepatocellular carcinoma (HCC). The mRNA-binding protein tristetraprolin (TTP, gene name )…”
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Kupffer cells are protective in alcoholic steatosis by Köhler, Nikolai, Höring, Marcus, Czepukojc, Beate, Rose, Tim Daniel, Buechler, Christa, Kröhler, Tarek, Haybaeck, Johannes, Liebisch, Gerhard, Pauling, Josch K, Kessler, Sonja M, Kiemer, Alexandra K

“…Massive accumulation of lipids is a characteristic of alcoholic liver disease. Excess of hepatic fat activates Kupffer cells (KCs), which affect disease…”
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THU-470-The mRNA-binding protein tristetraprolin promotes hepatocarcinogenesis but inhibits tumour progression in liver cancer by Kessler, Sonja, Hosseini, Kevan, Kröhler, Tarek, Barghash, Ahmad, Patial, Sonika, Hoppstädter, Jessica, Gemperlein, Katja, Haybäck, Johannes, List, Markus, Müller, Rolf, Helms, Volkhard, Schulz, Marcel, Laggai, Stephan, Blackshear, Perry, Kiemer, Alexandra K.

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