Search Results - "Krizanova, Olga"
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Role of the 3-mercaptopyruvate sulfurtransferase in colon/colorectal cancers
Published in European journal of cell biology (01-06-2024)“…The 3-mercaptopyruvate sulfurtransferase (MPST) is a protein persulfidase, occurring mainly in mitochondria. Although function of this protein in cancer cells…”
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2
Signaling pathways in cutaneous wound healing
Published in Frontiers in physiology (25-11-2022)“…Wound healing is a very complex process, where variety of different pathways is activated, depending on the phase of healing. Improper or interrupted healing…”
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3
Role of Sodium/Calcium Exchangers in Tumors
Published in Biomolecules (Basel, Switzerland) (31-08-2020)“…The sodium/calcium exchanger (NCX) is a unique calcium transport system, generally transporting calcium ions out of the cell in exchange for sodium ions…”
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4
Type 3 inositol 1,4,5-trisphosphate receptor has antiapoptotic and proliferative role in cancer cells
Published in Cell death & disease (22-02-2019)“…Although the involvement of type 1 (IP 3 R1) and type 2 (IP 3 R2) inositol 1,4,5-trisphosphate receptors in apoptosis induction has been well documented in…”
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Endogenous H2S producing enzymes are involved in apoptosis induction in clear cell renal cell carcinoma
Published in BMC cancer (24-05-2018)“…Background Knowledge about the expression and thus a role of enzymes that produce endogenous H.sub.2S - cystathionine-[beta]-synthase, cystathionine…”
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Camptothecin, triptolide, and apoptosis inducer kit have differential effects on mitochondria in colorectal carcinoma cells
Published in FEBS open bio (01-05-2022)“…Mitochondrial fission and fusion are required for cell survival, and several studies have shown an imbalance between fission and fusion in cancer. High levels…”
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Melatonin-Induced Changes in Cytosolic Calcium Might be Responsible for Apoptosis Induction in Tumour Cells
Published in Cellular physiology and biochemistry (01-01-2017)“…Background/Aims: Melatonin is a hormone transferring information about duration of darkness to the organism and is known to modulate several signaling pathways…”
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8
Cystathionine β-synthase affects organization of cytoskeleton and modulates carcinogenesis in colorectal carcinoma cells
Published in Frontiers in oncology (07-07-2023)“…Cystathionine β-synthase (CBS), one of three enzymes that endogenously produce hydrogen sulfide, is extensively studied for its relevance in the cells of…”
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Slow Sulfide Donor GYY4137 Increased the Sensitivity of Two Breast Cancer Cell Lines to Paclitaxel by Different Mechanisms
Published in Biomolecules (Basel, Switzerland) (01-06-2024)“…Paclitaxel (PTX) is a chemotherapeutic agent affecting microtubule polymerization. The efficacy of PTX depends on the type of tumor, and its improvement would…”
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10
Haloperidol Affects Plasticity of Differentiated NG-108 Cells Through σ1R/IP3R1 Complex
Published in Cellular and molecular neurobiology (2018)“…Haloperidol is an antipsychotic agent that primarily acts as an antagonist of D2 dopamine receptors. Besides other receptor systems, it targets sigma 1…”
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Long-Term Haloperidol Treatment Prolongs QT Interval and Increases Expression of Sigma 1 and IP3 Receptors in Guinea Pig Hearts
Published in The Tohoku Journal of Experimental Medicine (2015)“…Haloperidol is a neuroleptic drug used for a medication of various psychoses and deliria. Its administration is frequently accompanied by cardiovascular side…”
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12
Apoptosis induced clustering of IP3R1 in nuclei of non-differentiated PC12 cells
Published in Journal of cellular physiology (01-12-2011)“…Inositol 1,4,5‐trisphosphate (IP3) receptors are emerging as key sites for regulation by pro‐ and anti‐apoptotic factors. Induction of apoptosis for 3 h…”
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13
Regulation of Gene Expression of Catecholamine Biosynthetic Enzymes in Dopamine-β-Hydroxylase- and CRH-Knockout Mice Exposed to Stress
Published in Annals of the New York Academy of Sciences (01-12-2008)“…Norepinephrine‐deficient mice harbor a disruption of the gene for dopamine‐β‐hydroxylase (DBH‐KO). Corticotropin‐releasing hormone knockout mice (CRH‐KO) have…”
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Bongkrekic acid and atractyloside inhibits chloride channels from mitochondrial membranes of rat heart
Published in Biochimica et biophysica acta (2007)“…The aim of this work was to characterize the effect of bongkrekic acid (BKA), atractyloside (ATR) and carboxyatractyloside (CAT) on single channel properties…”
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15
Calcium and ROS: A mutual interplay
Published in Redox biology (01-12-2015)“…Calcium is an important second messenger involved in intra- and extracellular signaling cascades and plays an essential role in cell life and death decisions…”
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Involvement of calcium signaling in different types of cell death in cancer
Published in Neoplasma (01-03-2022)“…Programmed cell death is a basic feature of chemotherapeutic (and also radiotherapeutic) intervention. Induction of cell death in tumor cells aims to kill…”
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Type 1 and 2 IP3 Receptors Respond Differently to Catecholamines and Stress
Published in Annals of the New York Academy of Sciences (01-12-2008)“…Type 1 and 2 inositol 1,4,5‐trisphosphate (IP3) receptors have been found in cardiac tissue, although they are localized in different types of cells. While the…”
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Slow sulfide donor GYY4137 potentiates effect of paclitaxel on colorectal carcinoma cells
Published in European journal of pharmacology (05-05-2022)“…Although paclitaxel (PTX) is potent chemotherapeutic agent commonly used in variety of cancers, in colorectal carcinoma its usage is excluded because of low…”
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Localization and Regulation of Phenylethanolamine N-Methyltransferase Gene Expression in the Heart of Rats and Mice during Stress
Published in Annals of the New York Academy of Sciences (01-06-2004)“…: Recently we have described the existence of phenylethanolamine N‐methyltransferase (PNMT) mRNA in the heart of adult rats. In this study, we report the first…”
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Effect of Hyperhomocysteinemia on Redox Balance and Redox Defence Enzymes in Ischemia–Reperfusion Injury and/or After Ischemic Preconditioning in Rats
Published in Cellular and molecular neurobiology (01-11-2017)“…Increased level of homocysteine (hHcy) in plasma is an accompanying phenomenon of many diseases, including a brain stroke. This study determines whether…”
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