Search Results - "Kriz̆aj, I."

Nicotinic acetylcholine receptors in cancer: Limitations and prospects by Bele, T., Turk, T., Križaj, I.

“…Nicotinic acetylcholine receptors (nAChRs) have long been considered to solely mediate neurotransmission. However, their widespread distribution in the human…”
Get full text

An agonist of CXCR4 induces a rapid recovery from the neurotoxic effects of Vipera ammodytes and Vipera aspis venoms by Stazi, M., Megighian, A., D'Este, G., Negro, S., Ivanušec, A., Lonati, D., Pirazzini, M., Križaj, I., Montecucco, C.

“…People bitten by Alpine vipers are usually treated with antivenom antisera to prevent the noxious consequences caused by the injected venom. However, this…”
Get full text

The sensing of membrane microdomains based on pore-forming toxins by Skočaj, M, Bakrač, B, Križaj, I, Maček, P, Anderluh, G, Sepčić, K

“…Membrane rafts are transient and unstable membrane microdomains that are enriched in sphingolipids, cholesterol, and specific proteins. They are involved in…”
Get more information

Comparative electrophysiological characterization of ammodytoxin A, a β-neurotoxin from the nose-horned viper venom, and its enzymatically inactive mutant by Žužek, M.C., Ivanušec, A., Herman, J., Šribar, J., Leonardi, A., Frangež, R., Križaj, I.

“…Presynaptic- or β-neurotoxicity of secreted phospholipases A2 (sPLA2) is a complex process. For full expression of β-neurotoxicity, the enzymatic activity of…”
Get full text

High avidity anti-β2-glycoprotein I antibodies in patients with antiphospholipid syndrome by Čučnik, S, Kveder, T, Križaj, I, Rozman, B, Božič, B

“…Objective: To evaluate avidity of IgG anti-β2-glycoprotein I antibodies (anti-β2-GPI) in patients with antiphospholipid syndrome (APS) and systemic lupus…”
Get full text

Ultrastructural evidence for the uptake of a neurotoxic snake venom phospholipase A2 into mammalian motor nerve terminals by LOGONDER, U, JENKO-PRAZNIKAR, Z, SCOTT-DAVEY, T, PUNGERCAR, J, KRIZAJ, I, HARRIS, J. B

“…A mutant form of ammodytoxin A, a neurotoxic phospholipase A(2) from the venom of the long nosed viper Vipera ammodytes ammodytes, was prepared by…”
Get full text

Genetic interactions between a phospholipase A₂ and the Rim101 pathway components in S. cerevisiae reveal a role for this pathway in response to changes in membrane composition and shape by Mattiazzi, M, Jambhekar, A, Kaferle, P, DeRisi, J. L, Križaj, I, Petrovič, U

“…Modulating composition and shape of biological membranes is an emerging mode of regulation of cellular processes. We investigated the global effects that such…”
Get full text

New conopeptides of the D-superfamily selectively inhibiting neuronal nicotinic acetylcholine receptors by Kauferstein, S., Kendel, Y., Nicke, A., Coronas, F.I.V., Possani, L.D., Favreau, P., Križaj, I., Wunder, C., Kauert, G., Mebs, D.

“…The venom of cone snails ( Conus spp.) is a rich source of peptides exhibiting a wide variety of biological activities. Several of these conopeptides are…”
Get full text

Isolation and characterization of the Pseudobutyrivibrio xylanivorans Mz5 xylanase XynT--the first family 11 endoxylanase from rumen Butyrivibrio- related bacteria by Cepeljnik, T, Krizaj, I, Marinsek-Logar, R

“…Rumen bacterium Pseudobutyrivibrio xylanivorans Mz5 produces multiple xylanases that account for its high xylanolytic activity. The smallest xylanase (XynT)…”
Get full text

Isolation and characterization of the Pseudobutyrivibrio xylanivorans Mz5T xylanase XynT: the first family 11 endoxylanase from rumen Butyrivibrio-related bacteria by CEPELJNIK, T, KRIZAJ, I, MARINSEK-LOGAR, R

Get full text

N-terminal truncation mutagenesis of equinatoxin II, a pore-forming protein from the sea anemone Actinia equina by Anderluh, G, Pungercar, J, Krizaj, I, Strukelj, B, Gubensek, F, Macek, P

“…The role of the N-terminal segment 1-33 of equinatoxin II, a 20 kDa pore-forming protein from the sea anemone Actinia equina, was studied by N-truncation…”
Get full text

Charge reversal of ammodytoxin A, a phospholipase A2-toxin, does not abolish its neurotoxicity by Prijatelj, P, Copic, A, Krizaj, I, Gubensek, F, Pungercar, J

“…The positive charge concentrated at the C-terminal region of ammodytoxin (Atx) A, which is involved in presynaptic toxicity, has been reversed. A six-site…”
Get full text

Reversible thrombocytopenia of functional platelets after the nose-horned viper venom envenomation is induced by a snaclec by Križaj, I., Dobaja Borak, M., Leonardi, A., Požek, K., Reberšek, K., Podgornik, H., Pirnat, A., Trampuš Bakija, A., Kranjc Brezar, S., Trobec, T., Žužek, M., Frangež, R., Brvar, M.

Get full text

The primary structure of inhibitor of cysteine proteinases from potato by Kriz̆aj, I., Drobnic̆-Kos̆orok, M., Brzin, J., Jerala, R., Turk, V.

“…The complete amino acid sequence of the cysteine proteinase inhibitor from potato tubers was determined. The inhibitor is a single-chain protein having 180…”
Get full text

Bovine stefin C, a new member of the stefin family by Turk, B, Krizaj, I, Kralj, B, Dolenc, I, Popovic, T, Bieth, J.G, Turk, V

“…Four low Mr cysteine proteinase inhibitors with different pI values were isolated from bovine thymus using alkaline activation of the gland homogenate,…”
Get full text

Discovering innovative drugs and diagnostic tools to control haemostasis by venomics of the Vipera a. ammodytes snake by Leonardi, A., Sajevic, T., Križaj, I.

Get full text

Ammodytoxin A acceptor in bovine brain synaptic membranes by Kriz̆aj, I., Rowan, E.G., Gubens̆ek, F.

“…Ammodytoxin A, the presynaptic neurotoxin from Vipera ammodytes ammodytes venom, was found to bind specifically and with high affinity to bovine cortex…”
Get full text

Understanding the molecular mechanism underlying the presynaptic toxicity of secreted phospholipases A sub(2) by Pungercar, J, Krizaj, I

“…An important group of toxins, whose action at the molecular level is still a matter of debate, is secreted phospholipases A sub(2) (sPLA sub(2)s) endowed with…”
Get full text

Cathepsin D inactivates cysteine proteinase inhibitors, cystatins by Lenarcic, B, Kos, J, Dolenc, I, Lucovnik, P, Krizaj, I, Turk, V

“…The formation of inactive complexes in excess molar amounts of human cathepsins H and L with their protein inhibitors human stefin A, human stefin B and…”
Get more information

Nucleotide and deduced amino acid sequence of an aspartic proteinase inhibitor homologue from potato tubers (Solanum tuberosum L.) by STRUKELJ, B, PUNGERCAR, J, RITONJA, A, KRIZAJ, I, GUBENSEK, F, KREGAR, I, TURK, V

“…cDNA sequences of any aspartic proteinase inhibitors have not been reported so far. Two protein inhibitors of aspartic proteinases were isolated from potato…”
Get full text