Search Results - "Kristl, Vonck"
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Translational research to unravel the mechanism of action of vagus nerve stimulation
Published in Brain stimulation (01-11-2021)Get full text
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Functional brain connectivity from EEG in epilepsy: seizure prediction and epileptogenic focus localization
Published in Progress in neurobiology (01-10-2014)“…Today, neuroimaging techniques are frequently used to investigate the integration of functionally specialized brain regions in a network. Functional…”
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Resting-state networks and dissociation in psychogenic non-epileptic seizures
Published in Journal of psychiatric research (01-07-2014)“…Abstract Objective Psychogenic non-epileptic seizures (PNES) are epilepsy-like episodes which have an emotional rather than organic origin. Although PNES have…”
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The potential of invasive and non-invasive vagus nerve stimulation to improve verbal memory performance in epilepsy patients
Published in Scientific reports (07-02-2022)“…It has been demonstrated that acute vagus nerve stimulation (VNS) improves word recognition memory in epilepsy patients. Transcutaneous auricular vagus nerve…”
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Vagus nerve stimulation…25 years later! What do we know about the effects on cognition?
Published in Neuroscience and biobehavioral reviews (01-09-2014)“…VNS therapy was delivered to patients for the first time in 1988. After 25 years, insight in the antiepileptic and antidepressant mechanism of action of VNS…”
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The antidepressant mechanism of action of vagus nerve stimulation: Evidence from preclinical studies
Published in Neuroscience and biobehavioral reviews (01-09-2015)“…Vagus nerve stimulation (VNS) is a proposed neuromodulatory treatment for medically refractory major depression. Although VNS is already used in clinical…”
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International Consensus Based Review and Recommendations for Minimum Reporting Standards in Research on Transcutaneous Vagus Nerve Stimulation (Version 2020)
Published in Frontiers in human neuroscience (23-03-2021)“…Given its non-invasive nature, there is increasing interest in the use of transcutaneous vagus nerve stimulation (tVNS) across basic, translational and…”
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Vagus nerve stimulation in refractory and super-refractory status epilepticus – A systematic review
Published in Brain stimulation (01-09-2019)“…Refractory status epilepticus (RSE) is the persistence of status epilepticus despite second-line treatment. Super-refractory SE (SRSE) is characterized by…”
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Deep brain and cortical stimulation for epilepsy
Published in Cochrane database of systematic reviews (17-06-2014)“…Despite optimal medical treatment, including epilepsy surgery, many epilepsy patients have uncontrolled seizures. In the last decades, interest has grown in…”
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30 years of vagus nerve stimulation trials in epilepsy: Do we need neuromodulation-specific trial designs?
Published in Epilepsy research (01-07-2019)“…•Larger P300 amplitudes are found in VNS responders upon stimulation. P300 modulation by non-invasive VNS may be used to predict response to VNS.•12-week…”
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Autonomic nervous system functioning associated with psychogenic nonepileptic seizures: Analysis of heart rate variability
Published in Epilepsy & behavior (01-01-2016)“…Abstract Objective Psychogenic nonepileptic seizures (PNESs) resemble epileptic seizures but originate from psychogenic rather than organic causes. Patients…”
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Hippocampal seizures differentially modulate locus coeruleus activity and result in consistent time-locked release of noradrenaline in rat hippocampus
Published in Neurobiology of disease (01-12-2023)“…The locus coeruleus (LC) is a small brainstem nucleus and is the sole source of noradrenaline in the neocortex, hippocampus and cerebellum. Noradrenaline is a…”
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Recent Advances in the Use of Focused Ultrasound as a Treatment for Epilepsy
Published in Frontiers in neuroscience (20-06-2022)“…Epilepsy affects about 1% of the population. Approximately one third of patients with epilepsy are drug-resistant (DRE). Resective surgery is an effective…”
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Diagnostic methods and treatment options for focal cortical dysplasia
Published in Epilepsia (Copenhagen) (01-11-2015)“…Summary Our inability to adequately treat many patients with refractory epilepsy caused by focal cortical dysplasia (FCD), surgical inaccessibility and…”
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Increased hippocampal noradrenaline is a biomarker for efficacy of vagus nerve stimulation in a limbic seizure model
Published in Journal of neurochemistry (01-05-2011)“…J. Neurochem. (2011) 117, 461–469. Vagus nerve stimulation (VNS) is an effective adjunctive treatment for medically refractory epilepsy. In this study, we…”
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Transcutaneous Vagus Nerve Stimulation Does Not Affect Verbal Memory Performance in Healthy Volunteers
Published in Frontiers in psychology (15-04-2020)“…Invasive vagus nerve stimulation (VNS) improves word recognition memory in patients with epilepsy. Recent studies with transcutaneous VNS (tVNS) have also…”
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Long‐term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-11-2019)“…Objective More than one‐third of patients with temporal lobe epilepsy (TLE) continue to have seizures despite treatment with antiepileptic drugs, and many…”
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Vagus nerve stimulation enhances remyelination and decreases innate neuroinflammation in lysolecithin-induced demyelination
Published in Brain stimulation (01-05-2024)“…Current treatments for Multiple Sclerosis (MS) poorly address chronic innate neuroinflammation nor do they offer effective remyelination. The vagus nerve has a…”
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A prospective, multicenter study of cardiac-based seizure detection to activate vagus nerve stimulation
Published in Seizure (London, England) (01-11-2015)“…Highlights • First clinical trial in epilepsy with combined open and closed-loop VNS. • Cardiac-based seizure detection had greater than 80% sensitivity. •…”
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Long‐term chemogenetic suppression of seizures in a multifocal rat model of temporal lobe epilepsy
Published in Epilepsia (Copenhagen) (01-03-2021)“…Summary Objective One third of epilepsy patients do not become seizure‐free using conventional medication. Therefore, there is a need for alternative…”
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