Search Results - "Kristian, Taipale"

Oncolytic adenovirus decreases the proportion of TIM-3+ subset of tumor-infiltrating CD8+ T cells with correlation to improved survival in patients with cancer by Liikanen, Ilkka, Basnet, Saru, Quixabeira, Dafne C A, Taipale, Kristian, Hemminki, Otto, Oksanen, Minna, Kankainen, Matti, Juhila, Juuso, Kanerva, Anna, Joensuu, Timo, Tähtinen, Siri, Hemminki, Akseli

“…BackgroundOncolytic viruses are a potent form of active immunotherapy, capable of invoking antitumor T-cell responses. Meanwhile, less is known about their…”
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T-cell Subsets in Peripheral Blood and Tumors of Patients Treated With Oncolytic Adenoviruses by Kristian, Taipale, Ilkka, Liikanen, Juuso, Juhila, Aila, Karioja-Kallio, Minna, Oksanen, Riku, Turkki, Nina, Linder, Johan, Lundin, Ari, Ristimäki, Anna, Kanerva, Anniina, Koski, Timo, Joensuu, Markus, Vähä-Koskela, Akseli, Hemminki

“…The quality of the antitumor immune response is decisive when developing new immunotherapies for cancer. Oncolytic adenoviruses cause a potent immunogenic…”
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Oncograms Visualize Factors Influencing Long-Term Survival of Cancer Patients Treated with Adenoviral Oncolytic Immunotherapy by Hemminki, Otto, Oksanen, Minna, Taipale, Kristian, Liikanen, Ilkka, Koski, Anniina, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli

“…The first US Food and Drug Administration (FDA)- and EMA-approved oncolytic virus has been available since 2015. However, there are no markers available that…”
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Overcoming tumor resistance by heterologous adeno-poxvirus combination therapy by Vähä-Koskela, Markus, Tähtinen, Siri, Grönberg-Vähä-Koskela, Susanna, Taipale, Kristian, Saha, Dipongkor, Merisalo-Soikkeli, Maiju, Ahonen, Marko, Rouvinen-Lagerström, Noora, Hirvinen, Mari, Veckman, Ville, Matikainen, Sampsa, Zhao, Fang, Pakarinen, Päivi, Salo, Jarmo, Kanerva, Anna, Cerullo, Vincenzo, Hemminki, Akseli

“…Successful cancer control relies on overcoming resistance to cell death and on activation of host antitumor immunity. Oncolytic viruses are particularly…”
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Risk-stratified analysis of long-term clinical outcomes and cumulative costs in Finnish patients with recent acute coronary syndrome or coronary revascularization: a 5-year real-world study using electronic health records by Oksanen, Minna, Parviainen, Jenna, Asseburg, Christian, Hageman, Steven, Rissanen, Tuomas T, Kivelä, Annukka, Taipale, Kristian, Visseren, Frank, Martikainen, Janne

“…Risk assessment is essential in the prevention of cardiovascular disease. In patients with recent acute coronary syndrome (ACS) or coronary revascularization,…”
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418. Peripheral Blood Leucocytes, Neutralizing Antibodies and Tumor Burden as Predictive and Prognostic Factors in Patients Treated with Oncolytic Adenoviral Immunotherapy by Parviainen, Suvi, Taipale, Kristian, Liikanen, Ilkka, Koski, Anniina, Kanerva, Anna, Oksanen, Minna, Hemminki, Akseli

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Predictive and Prognostic Clinical Variables in Cancer Patients Treated With Adenoviral Oncolytic Immunotherapy by Taipale, Kristian, Liikanen, Ilkka, Koski, Anniina, Heiskanen, Raita, Kanerva, Anna, Hemminki, Otto, Oksanen, Minna, Grönberg-Vähä-Koskela, Susanna, Hemminki, Kari, Joensuu, Timo, Hemminki, Akseli

“…The development of oncolytic viruses has recently made great progress towards being available to cancer patients. With the breakthrough into clinics, it is…”
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Interleukin 8 activity influences the efficacy of adenoviral oncolytic immunotherapy in cancer patients by Taipale, Kristian, Tähtinen, Siri, Havunen, Riikka, Koski, Anniina, Liikanen, Ilkka, Pakarinen, Päivi, Koivisto-Korander, Riitta, Kankainen, Matti, Joensuu, Timo, Kanerva, Anna, Hemminki, Akseli

“…After the landmark approval of T-VEC, oncolytic viruses are finding their way to the clinics. However, response rates have still room for improvement, and…”
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Chronic Activation of Innate Immunity Correlates With Poor Prognosis in Cancer Patients Treated With Oncolytic Adenovirus by Taipale, Kristian, Liikanen, Ilkka, Juhila, Juuso, Turkki, Riku, Tähtinen, Siri, Kankainen, Matti, Vassilev, Lotta, Ristimäki, Ari, Koski, Anniina, Kanerva, Anna, Diaconu, Iulia, Cerullo, Vincenzo, Vähä-Koskela, Markus, Oksanen, Minna, Linder, Nina, Joensuu, Timo, Lundin, Johan, Hemminki, Akseli

“…Despite many clinical trials conducted with oncolytic viruses, the exact tumor-level mechanisms affecting therapeutic efficacy have not been established…”
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Prognostic and predictive factors in therapy with oncolytic adenoviruses by Koski, Anniina, Heiskanen, Raita, Taipale, Kristian, Partanen, Kaarina, Joensuu, Timo, Hemminki, Akseli

“…286 patients with advanced chemotherapy refractory solid tumors were treated in a personalized manner in the Advanced Therapy Access Program. Presented here is…”
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Analysis of predictive and prognostic factors in 290 patients treated with oncolytic adenoviruses by Taipale, Kristian, Liikanen, Ilkka, Koski, Anniina, Kanerva, Anna, Oksanen, Minna, Hemminki, Akseli

“…BackgroundAfter years of development, oncolytic viruses are nearing a breakthrough into clinical use. In order to facilitate the implementation of this new…”
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