Search Results - "Kristensen, W."

Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells by Schonberg, David L., Miller, Tyler E., Wu, Qiulian, Flavahan, William A., Das, Nupur K., Hale, James S., Hubert, Christopher G., Mack, Stephen C., Jarrar, Awad M., Karl, Robert T., Rosager, Ann Mari, Nixon, Anne M., Tesar, Paul J., Hamerlik, Petra, Kristensen, Bjarne W., Horbinski, Craig, Connor, James R., Fox, Paul L., Lathia, Justin D., Rich, Jeremy N.

“…Glioblastomas display hierarchies with self-renewing cancer stem-like cells (CSCs). RNA sequencing and enhancer mapping revealed regulatory programs unique to…”
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Expression and prognostic impact of matrix metalloproteinase-2 (MMP-2) in astrocytomas by Ramachandran, Rahimsan K, Sørensen, Mia D, Aaberg-Jessen, Charlotte, Hermansen, Simon K, Kristensen, Bjarne W

“…Astrocytomas are the most frequent primary brain tumors in adults, and despite aggressive treatment patients often experience recurrence. Survival decreases…”
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Transferrin receptor-1 and ferritin heavy and light chains in astrocytic brain tumors: Expression and prognostic value by Rosager, Ann Mari, Sørensen, Mia D, Dahlrot, Rikke H, Hansen, Steinbjørn, Schonberg, David L, Rich, Jeremy N, Lathia, Justin D, Kristensen, Bjarne W

“…Astrocytic brain tumors are the most frequent primary brain tumors. Treatment with radio- and chemotherapy has increased survival making prognostic biomarkers…”
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The presence of TIM‐3 positive cells in WHO grade III and IV astrocytic gliomas correlates with isocitrate dehydrogenase mutation status by D. Sørensen, Mia, Nielsen, Ole, Reifenberger, Guido, W. Kristensen, Bjarne

“…Diffuse gliomas are aggressive brain tumors that respond poorly to immunotherapy including immune checkpoint inhibition. This resistance may arise from an…”
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Drought in Africa Caused Delayed Arrival of European Songbirds by Tøttrup, A. P., Klaassen, R. H. G., Kristensen, M. W., Strandberg, R., Vardanis, Y., Lindström, Å., Rahbek, C., Alerstam, T., Thorup, K.

“…Despite an overall advancement in breeding area arrival, one of the latest spring arrivals in northwest Europe since 1950 of several trans-Saharan songbird…”
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Cancer Stem Cell‐Secreted Macrophage Migration Inhibitory Factor Stimulates Myeloid Derived Suppressor Cell Function and Facilitates Glioblastoma Immune Evasion by Otvos, Balint, Silver, Daniel J., Mulkearns‐Hubert, Erin E., Alvarado, Alvaro G., Turaga, Soumya M., Sorensen, Mia D., Rayman, Patricia, Flavahan, William A, Hale, James S., Stoltz, Kevin, Sinyuk, Maksim, Wu, Qiulian, Jarrar, Awad, Kim, Sung‐Hak, Fox, Paul L., Nakano, Ichiro, Rich, Jeremy N., Ransohoff, Richard M., Finke, James, Kristensen, Bjarne W., Vogelbaum, Michael A., Lathia, Justin D.

“…Shifting the balance away from tumor‐mediated immune suppression toward tumor immune rejection is the conceptual foundation for a variety of immunotherapy…”
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Geolocation by light: accuracy and precision affected by environmental factors by Lisovski, Simeon, Hewson, Chris M., Klaassen, Raymond H. G., Korner‐Nievergelt, Fränzi, Kristensen, Mikkel W., Hahn, Steffen

“…Summary 1. Geolocation by light allows for tracking animal movements, based on measurements of light intensity over time by a data‐logging device…”
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Prognostic role of Ki-67 in glioblastomas excluding contribution from non-neoplastic cells by Dahlrot, Rikke H., Bangsø, Julie A., Petersen, Jeanette K., Rosager, Ann Mari, Sørensen, Mia D., Reifenberger, Guido, Hansen, Steinbjørn, Kristensen, Bjarne W.

“…Survival of glioblastoma patients varies and prognostic markers are important in the clinical setting. With digital pathology and improved immunohistochemical…”
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Chronic pre-operative opioid use and acute pain after fast-track total knee arthroplasty by Aasvang, E. K., Lunn, T. H., Hansen, T. B., Kristensen, P. W., Solgaard, S., Kehlet, H.

“…Background Pre‐operative opioid use has been suggested to increase post‐operative pain and opioid consumption after total knee arthroplasty (TKA), but previous…”
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Altered lipid metabolism marks glioblastoma stem and non-stem cells in separate tumor niches by Shakya, Sajina, Gromovsky, Anthony D, Hale, James S, Knudsen, Arnon M, Prager, Briana, Wallace, Lisa C, Penalva, Luiz O F, Brown, H Alex, Kristensen, Bjarne W, Rich, Jeremy N, Lathia, Justin D, Brown, J Mark, Hubert, Christopher G

“…Glioblastoma (GBM) displays marked cellular and metabolic heterogeneity that varies among cellular microenvironments within a tumor. Metabolic targeting has…”
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Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke by Clausen, Bettina H, Wirenfeldt, Martin, Høgedal, Sofie S, Frich, Lars H, Nielsen, Helle H, Schrøder, Henrik D, Østergaard, Kamilla, Finsen, Bente, Kristensen, Bjarne W, Lambertsen, Kate L

“…Preclinical and clinical proof-of-concept studies have suggested the effectiveness of pharmacological modulation of inflammatory cytokines in ischemic stroke…”
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GDNF/GFRA1 signaling contributes to chemo- and radioresistance in glioblastoma by Avenel, Inès C. N., Ewald, Jesper D., Ariey-Bonnet, Jérémy, Kristensen, Ida H., Petterson, Stine A., Thesbjerg, Martin N., Burton, Mark, Thomassen, Mads, Wennerberg, Krister, Michaelsen, Signe R., Kristensen, Bjarne W.

“…Glioblastoma is the most common primary brain tumor in adults, characterized by an inherent aggressivity and resistance to treatment leading to poor prognoses…”
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A 4-miRNA signature to predict survival in glioblastomas by Hermansen, Simon K, Sørensen, Mia D, Hansen, Anker, Knudsen, Steen, Alvarado, Alvaro G, Lathia, Justin D, Kristensen, Bjarne W

“…Glioblastomas are among the most lethal cancers; however, recent advances in survival have increased the need for better prognostic markers. microRNAs (miRNAs)…”
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Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas by Aaberg-Jessen, Charlotte, Sørensen, Mia D, Matos, Ana L S A, Moreira, José M, Brünner, Nils, Knudsen, Arnon, Kristensen, Bjarne W

“…We have previously identified tissue inhibitor of metalloproteinases-1 (TIMP-1) as a prognostic marker in glioblastomas. TIMP-1 has been associated with…”
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Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo by Jensen, Stine S, Petterson, Stine A, Halle, Bo, Aaberg-Jessen, Charlotte, Kristensen, Bjarne W

“…Glioblastoma is the most frequent and most malignant brain tumor with the patients having a median survival of only 14.6 months. Although glioblastoma patients…”
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Inconsistent Immunohistochemical Expression Patterns of Four Different CD133 Antibody Clones in Glioblastoma by Hermansen, Simon K., Christensen, Karina G., Jensen, Stine S., Kristensen, Bjarne W.

“…The putative tumor stem cell marker CD133 is the marker of choice for identifying brain tumor stem cells in gliomas, but the use of different CD133 antibody…”
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The Prognostic Value of Methylation Signatures and NF2 Mutations in Atypical Meningiomas by Meta, Rahmina, Boldt, Henning B, Kristensen, Bjarne W, Sahm, Felix, Sjursen, Wenche, Torp, Sverre H

“…: Due to the solely subjective histopathological assessment, the WHO 2016 classification of human meningiomas is subject to interobserver variation…”
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Targeted next‐generation sequencing of adult gliomas for retrospective prognostic evaluation and up‐front diagnostics by Petersen, J. K., Boldt, H. B., Sørensen, M. D., Blach, S., Dahlrot, R. H., Hansen, S., Burton, M., Thomassen, M., Kruse, T., Poulsen, F. R., Andreasen, L., Hager, H., Ulhøi, B. P., Lukacova, S., Reifenberger, G., Kristensen, B. W.

“…Aims We aimed to reclassify a population‐based cohort of 529 adult glioma patients to evaluate the prognostic impact of the 2016 World Health Organization…”
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Asymmetric cell division promotes therapeutic resistance in glioblastoma stem cells by Hitomi, Masahiro, Chumakova, Anastasia P, Silver, Daniel J, Knudsen, Arnon M, Pontius, W Dean, Murphy, Stephanie, Anand, Neha, Kristensen, Bjarne W, Lathia, Justin D

“…Asymmetric cell division (ACD) enables the maintenance of a stem cell population while simultaneously generating differentiated progeny. Cancer stem cells…”
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APNG as a prognostic marker in patients with glioblastoma by Fosmark, Sigurd, Hellwege, Sofie, Dahlrot, Rikke H, Jensen, Kristian L, Derand, Helene, Lohse, Jesper, Sørensen, Mia D, Hansen, Steinbjørn, Kristensen, Bjarne W

“…Expression of the base excision repair enzyme alkylpurine-DNA-N-glycosylase (APNG) has been correlated to temozolomide resistance. Our aim was to evaluate the…”
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