Search Results - "Kristensen, Line"

GPR119, a Major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Coacting in Synergy With FFA1 (GPR40) by Ekberg, Jeppe H, Hauge, Maria, Kristensen, Line V, Madsen, Andreas N, Engelstoft, Maja S, Husted, Anna-Sofie, Sichlau, Rasmus, Egerod, Kristoffer L, Timshel, Pascal, Kowalski, Timothy J, Gribble, Fiona M, Reiman, Frank, Hansen, Harald S, Howard, Andrew D, Holst, Birgitte, Schwartz, Thue W

“…Triglycerides (TGs) are among the most efficacious stimulators of incretin secretion; however, the relative importance of FFA1 (G Protein-coupled Receptor…”
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Structure and Interactions of HIV-1 gp41 CHR-NHR Reverse Hairpin Constructs Reveal Molecular Determinants of Antiviral Activity by He, Li, McAndrew, Ryan, Barbu, Razvan, Gifford, Grant, Halacoglu, Cari, Drouin-Allaire, Camille, Weber, Lindsey, Kristensen, Line G., Gupta, Sayan, Chen, Yan, Petzold, Christopher J., Allaire, Marc, Li, Kathy H., Ralston, Corie Y., Gochin, Miriam

“…[Display omitted] •N- and C-terminal helices of HIV gp41 coalesce into hairpin trimers upon fusion.•Mini-proteins containing truncated C-helix followed by…”
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Inhibitors of histone demethylases by Lohse, Brian, Kristensen, Jesper L., Kristensen, Line H., Agger, Karl, Helin, Kristian, Gajhede, Michael, Clausen, Rasmus P.

“…Methylated lysines are important epigenetic marks. The enzymes involved in demethylation have recently been discovered and found to be involved in cancer…”
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Hydroxyl radical mediated damage of proteins in low oxygen solution investigated using X‐ray footprinting mass spectrometry by Kristensen, Line G., Holton, James M., Rad, Behzad, Chen, Yan, Petzold, Christopher J., Gupta, Sayan, Ralston, Corie Y.

“…In the method of X‐ray footprinting mass spectrometry (XFMS), proteins at micromolar concentration in solution are irradiated with a broadband X‐ray source,…”
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Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells by Engelstoft, Maja S, Park, Won-mee, Sakata, Ichiro, Kristensen, Line V, Husted, Anna Sofie, Osborne-Lawrence, Sherri, Piper, Paul K, Walker, Angela K, Pedersen, Maria H, Nøhr, Mark K, Pan, Jie, Sinz, Christopher J, Carrington, Paul E, Akiyama, Taro E, Jones, Robert M, Tang, Cong, Ahmed, Kashan, Offermanns, Stefan, Egerod, Kristoffer L, Zigman, Jeffrey M, Schwartz, Thue W

“…Abstract The molecular mechanisms regulating secretion of the orexigenic-glucoregulatory hormone ghrelin remain unclear. Based on qPCR analysis of…”
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Residue-Specific Epitope Mapping of the PD-1/Nivolumab Interaction Using X-ray Footprinting Mass Spectrometry by Kristensen, Line G, Gupta, Sayan, Chen, Yan, Petzold, Christopher J, Ralston, Corie Y

“…X-ray footprinting coupled with mass spectrometry (XFMS) presents a novel approach in structural biology, offering insights into protein conformation and…”
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Studies of H3K4me3 demethylation by KDM5B/Jarid1B/PLU1 reveals strong substrate recognition in vitro and identifies 2,4‐pyridine‐dicarboxylic acid as an in vitro and in cell inhibitor by Kristensen, Line H., Nielsen, Anders L., Helgstrand, Charlotte, Lees, Michael, Cloos, Paul, Kastrup, Jette S., Helin, Kristian, Olsen, Lars, Gajhede, Michael

“…Dynamic methylations and demethylations of histone lysine residues are important for gene regulation and are facilitated by histone methyltransferases and…”
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Mass spectrometry analyses of normal and polyglutamine expanded ataxin-3 reveal novel interaction partners involved in mitochondrial function by Kristensen, Line V., Oppermann, Felix S., Rauen, Matthias J., Fog, Karina, Schmidt, Thorsten, Schmidt, Jana, Harmuth, Tina, Hartmann-Petersen, Rasmus, Thirstrup, Kenneth

“…Deubiquitinating enzymes (DUBs) play important roles in a variety of cellular processes, including regulation of protein homeostasis. The DUB ataxin-3 is an…”
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Standardization of the Prosody in Use Battery (PUB): a speech prosody perception test in Danish by Morris, David Jackson, Burholt Kristensen, Line, Tøndering, John

“…Assessment of prosody perception may be useful in a number of clinical scenarios, including the rehabilitation of cochlear implant recipients. It is with this…”
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Spread-out Bragg peak FLASH: quantifying normal tissue toxicity in a murine model by Kristensen, Line, Poulsen, Per Rugaard, Kanouta, Eleni, Rohrer, Sky, Ankjærgaard, Christina, Andersen, Claus E, Johansen, Jacob G, Simeonov, Yuri, Weber, Uli, Grau, Cai, Sørensen, Brita Singers

“…A favorable effect of ultra-high dose rate (FLASH) radiation on normal tissue-sparing has been indicated in several preclinical studies. In these studies, the…”
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Releasing the brakes in coagulation Factor IXa by co-operative maturation of the substrate-binding site by Kristensen, Line Hyltoft, Olsen, Ole H, Blouse, Grant E, Brandstetter, Hans

“…Coagulation Factor IX is positioned at the merging point of the intrinsic and extrinsic blood coagulation cascades. Factor IXa (activated Factor IX) serves as…”
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Laboratory Evolution of a Saccharomyces cerevisiae × S. eubayanus Hybrid Under Simulated Lager-Brewing Conditions by Gorter de Vries, Arthur R, Voskamp, Maaike A, van Aalst, Aafke C A, Kristensen, Line H, Jansen, Liset, van den Broek, Marcel, Salazar, Alex N, Brouwers, Nick, Abeel, Thomas, Pronk, Jack T, Daran, Jean-Marc G

“…lager-brewing yeasts are domesticated hybrids of x that display extensive inter-strain chromosome copy number variation and chromosomal recombinations. It is…”
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Polyglutamine expansion of ataxin-3 alters its degree of ubiquitination and phosphorylation at specific sites by Kristensen, Line V., Oppermann, Felix S., Rauen, Matthias J., Hartmann-Petersen, Rasmus, Thirstrup, Kenneth

“…Ubiquitination and phosphorylation of proteins represent post translational modifications (PTMs) capable of regulating a variety of cellular processes. In the…”
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The Role of Non-Selective TNF Inhibitors in Demyelinating Events by Kristensen, Line Buch, Lambertsen, Kate Lykke, Nguyen, Nina, Byg, Keld-Erik, Nielsen, Helle H

“…The use of non-selective tumor necrosis factor (TNF) inhibitors is well known in the treatment of inflammatory diseases such as rheumatoid arthritis, Crohn's…”
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Identification of catechols as histone–lysine demethylase inhibitors by Nielsen, Anders L., Kristensen, Line H., Stephansen, Karen B., Kristensen, Jan B.L., Helgstrand, Charlotte, Lees, Michael, Cloos, Paul, Helin, Kristian, Gajhede, Michael, Olsen, Lars

“…► Catechols were identified as inhibitors of the histone–lysine demethylase KDM4C. ► The inhibitors were selective towards KDM4C and KDM6A and had no effect on…”
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Molecular architecture of the Jumonji C family histone demethylase KDM5B by Dorosz, Jerzy, Kristensen, Line Hyltoft, Aduri, Nanda G., Mirza, Osman, Lousen, Rikke, Bucciarelli, Saskia, Mehta, Ved, Sellés-Baiget, Selene, Solbak, Sara Marie Øie, Bach, Anders, Mesa, Pablo, Hernandez, Pablo Alcon, Montoya, Guillermo, Nguyen, Tam T. T. N., Rand, Kasper D., Boesen, Thomas, Gajhede, Michael

“…The full length human histone 3 lysine 4 demethylase KDM5B (PLU-1/Jarid1B) has been studied using Hydrogen/Deuterium exchange mass spectrometry, homology…”
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K(v) 7 (KCNQ) channel openers normalize central 2-deoxyglucose uptake in a mouse model of mania and increase prefrontal cortical and hippocampal serine-9 phosphorylation levels of GSK3β by Kristensen, Line V, Sandager-Nielsen, Karin, Hansen, Henrik H

“…Several metabolic neuroimaging studies have indicated that bipolar patients with mania exhibit alterations in metabolic activity, suggesting that perturbations…”
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Peptides Derived from Histone 3 and Modified at Position 18 Inhibit Histone Demethylase KDM6 Enzymes by Jones, Sarah E., Olsen, Lars, Dorosz, Jerzy, Seger, Signe T., Andersson, Jan L., Kristensen, Line H., Gajhede, Michael

“…The KDM6 subfamily of histone lysine demethylases has recently been implicated as a putative target in the treatment of a number of diseases; this makes the…”
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The interface between language and attention: prosodic focus marking recruits a general attention network in spoken language comprehension by Kristensen, Line Burholt, Wang, Lin, Petersson, Karl Magnus, Hagoort, Peter

“…In spoken language, pitch accent can mark certain information as focus, whereby more attentional resources are allocated to the focused information. Using…”
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Not all grammar errors are equally noticed: error detection of naturally occurring errors and implications for eye-tracking models of everyday texts by Søby, Katrine Falcon, Ishkhanyan, Byurakn, Kristensen, Line Burholt

“…Grammar errors are a natural part of everyday written communication. They are not a uniform group, but vary from morphological errors to ungrammatical word…”
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