Search Results - "Krishnaraj, K. U."

Synthesis of 2-hydroxy-5,6-diarylnicotinonitriles and 2-chloro-5,6-diarylnicotinonitriles from β-chloroenones by Krishnaraj, K.U., Devaky, K.S.

“…Vilsmeier–Haack reaction of β-ketoaldehydes leads to the formation of β-chloroenones and these chloroenones on treatment with malononitrile afford…”
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Insulin Signalling: Essential Role of a 222 Da Molecular Mediator, Co-Insulin (Co-Ins) by Thampan, Raghava Varman, Krishnaraj, K. U., Ali, H. Shabeer, Kannan, Sapna, Mrudhula, C., Aravindakumar, C. T., Haridas, M.

“…An attempt has been made to probe into the molecular basis of insulin resistance. The target was to look into the existence of a molecule that could interfere…”
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A Facile One-Pot Synthesis of Chloropyridines from Chalcones by Menon, Prasanth K., Krishnaraj, K. U., George, Sholly C., Devaky, K. S., Anabha, E. R.

“…Malononitrile undergoes Michael addition to iminoalkylated chalcones under Vilsmeier–Haack reaction condition. In situ intramolecular cyclization followed by…”
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Synthesis, crystal structure and electron density analysis of a sulfanyl 2-pyridone analogue: Tautomeric preference and conformation locking by S···O chalcogen bonding by Menon, Prasanth K., Krishnaraj, K.U., Anabha, E.R., Devaky, K.S., Thomas, Sajesh P.

“…The effect of intra-molecular chalcogen bonding involving S(sp3)···O(sp2) interaction in locking the molecular conformation has been investigated in…”
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Simple methods to synthesize 2-pyridones: reactions of 2-aroyl-3,3-bis(alkylsulfanyl)acrylaldehydes and cyanoacetamide by Mathews, Annie, Anabha, E.R., Sasikala, K.A., Lathesh, K.C., Krishnaraj, K.U., Sreedevi, K.N., Prasanth, M., Devaky, K.S., Asokan, C.V.

“…5-Aroyl-6-(methylsulfanyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitriles and 5-aroyl-4-(methylsulfanyl)-2-oxo-1,2-dihydro-3-pyridinecarbonitriles are synthesized…”
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