Search Results - "Krishnan, Vidhya G."

Automated inference of molecular mechanisms of disease from amino acid substitutions by Li, Biao, Krishnan, Vidhya G., Mort, Matthew E., Xin, Fuxiao, Kamati, Kishore K., Cooper, David N., Mooney, Sean D., Radivojac, Predrag

“…Motivation: Advances in high-throughput genotyping and next generation sequencing have generated a vast amount of human genetic variation data. Single…”
Get full text

326-LB: BCL-xL/BCL2L1 Is a Critical Anti-Apoptotic Protein that Suppresses BAK to Promote Pancreatic Specification from Human Pluripotent Stem Cells by SAI WENG LOO, LARRY, TEO, ADRIAN, GHOSH, SOUMITA, ALVIN PURNOMO SOETEDJO, ANDREAS, NGUYEN, LINH, KRISHNAN, VIDHYA G., HOON, SHAWN

“…The differentiation of human pluripotent stem cells (hPSCs) into desired cell types such as the pancreatic cells involve cellular proliferation and apoptosis…”
Get full text

Whole-genome sequencing of asian lung cancers: second-hand smoke unlikely to be responsible for higher incidence of lung cancer among Asian never-smokers by Krishnan, Vidhya G, Ebert, Philip J, Ting, Jason C, Lim, Elaine, Wong, Swee-Seong, Teo, Audrey S M, Yue, Yong G, Chua, Hui-Hoon, Ma, Xiwen, Loh, Gary S L, Lin, Yuhao, Tan, Joanna H J, Yu, Kun, Zhang, Shenli, Reinhard, Christoph, Tan, Daniel S W, Peters, Brock A, Lincoln, Stephen E, Ballinger, Dennis G, Laramie, Jason M, Nilsen, Geoffrey B, Barber, Thomas D, Tan, Patrick, Hillmer, Axel M, Ng, Pauline C

“…Asian nonsmoking populations have a higher incidence of lung cancer compared with their European counterparts. There is a long-standing hypothesis that the…”
Get full text

In silico functional profiling of human disease-associated and polymorphic amino acid substitutions by Mort, Matthew, Evani, Uday S, Krishnan, Vidhya G, Kamati, Kishore K, Baenziger, Peter H, Bagchi, Angshuman, Peters, Brandon J, Sathyesh, Rakesh, Li, Biao, Sun, Yanan, Xue, Bin, Shah, Nigam H, Kann, Maricel G, Cooper, David N, Radivojac, Predrag, Mooney, Sean D

“…An important challenge in translational bioinformatics is to understand how genetic variation gives rise to molecular changes at the protein level that can…”
Get full text

Predicting cancer drivers: are we there yet? by Krishnan, Vidhya G, Ng, Pauline C

“…Genomic variants with a key role in causing cancer or affecting the response to cancer therapeutics need to be identified so that they can be targeted for…”
Get full text

Bioinformatic tools for identifying disease gene and SNP candidates by Mooney, Sean D, Krishnan, Vidhya G, Evani, Uday S

“…As databases of genome data continue to grow, our understanding of the functional elements of the genome grows as well. Many genetic changes in the genome have…”
Get more information