Search Results - "Krishnan, Raman"

Impact of problematic internet use on the self-esteem of adolescents in the selected school, Kerala, India by Mathew, Preeti, Krishnan, Raman

“…Internet use is one of the essential tools of our present-day society whose impact is seen on adolescents such as increased use of the internet because they…”
Get full text

Outcomes of early versus delayed cholecystectomy in patients with mild to moderate acute biliary pancreatitis: A randomized prospective study by Jee, Shir Li, Jarmin, Razman, Lim, Kin Foong, Raman, Krishnan

“…Abstract Background In patients with acute biliary pancreatitis (ABP), cholecystectomy is mandatory to prevent further biliary events, but the precise timing…”
Get full text

Regioselective alkylation of a versatile indazole: Electrophile scope and mechanistic insights from density functional theory calculations by Lu, Pengcheng, Juarez, Luis, Wiget, Paul A, Zhang, Weihe, Raman, Krishnan, Kotian, Pravin L

“…Herein, we report a pair of regioselective - and alkylations of a versatile indazole, methyl 5-bromo-1 -indazole-3-carboxylate ( ) and the use of density…”
Get full text

Synthesis of novel azasugar-containing 2'β-C-Me 9-deaza nucleosides as potential anti-hepatitis C virus agents by Kotian, Pravin L., Wu, Minwan, Ghosh, Ajit, Polach, Kevin J., El-Kattan, Yahya, Kumar, V. Satish, Lin, Tsu-Hsing, Cheng, Xiaogang, Bantia, Shanta, Raman, Krishnan, Chand, Pooran, Babu, Yarlagadda S.

“…As a part of our ongoing discovery efforts exploring azasugar as agents for treating various unmet medical needs, we prepared analogs of azasugar as potential…”
Get full text

Pancreatic hemangioma mimicking a malignant pancreatic cyst by Lee, Jarrod, MBBS, Raman, Krishnan, MBBS, Sachithanandan, Sharmila, MBBCh, BAO

Get full text

Cystic pheochromocytoma mimicking a malignant pancreatic cyst by Lee, Jarrod, MBBS, Raman, Krishnan, MBBS, Sachithanandan, Sharmila, MBBCh, BAO

Get full text

Safety of Percutaneous vs Open Tracheostomy on Intubated Patients in ICU Setting: Which One is Better? by Maheshwaran, S., Thomas, Sara V., Raman, Gopala Krishnan, Pookamala, S.

“…To study the safety of percutaneous vs open tracheostomy approaches on patients requiring long term ventilation in ICU setting. It is a prospective study done…”
Get full text

A comparative study of clinical correlates of bipolar mixed state with bipolar manic and bipolar depressed state in a general hospital psychiatry setting by Raman Krishnan, Sharma PSVN

“…Background: Mixed states pose diagnostic dilemmas and raise the question of their existence as separate diagnostic category. There are few Indian studies on…”
Get full text

Channel Models and Detectors for Two-Dimensional Magnetic Recording by Chan, Kheong Sann, Radhakrishnan, Rathnakumar, Eason, Kwaku, Elidrissi, Moulay Rachid, Miles, Jim J., Vasic, Bane, Krishnan, Anantha Raman

“…Two-dimensional magnetic recording (TDMR) is a novel recording architecture intended to support densities beyond those of conventional recording systems. The…”
Get full text

Crystal structure of vaccinia virus uracil-DNA glycosylase reveals dimeric assembly by Schormann, Norbert, Grigorian, Alexei, Samal, Alexandra, Krishnan, Raman, DeLucas, Lawrence, Chattopadhyay, Debasish

“…Uracil-DNA glycosylases (UDGs) catalyze excision of uracil from DNA. Vaccinia virus, which is the prototype of poxviruses, encodes a UDG (vvUDG) that is…”
Get full text

Design, parallel synthesis, and crystal structures of biphenyl antithrombotics as selective inhibitors of tissue factor FVIIa complex. Part 1: Exploration of S2 pocket pharmacophores by Kotian, Pravin L., Krishnan, Raman, Rowland, Scott, El-Kattan, Yahya, Saini, Surendra K., Upshaw, Ramanda, Bantia, Shanta, Arnold, Shane, Sudhakar Babu, Y., Chand, Pooran

“…Factor VIIa (FVIIa), a serine protease enzyme, coupled with tissue factor (TF) plays an important role in a number of thrombosis-related disorders. Inhibition…”
Get full text

EGCG mediated downregulation of NF-AT and macrophage infiltration in experimental hepatic steatosis by Krishnan, Thulasi Raman, Velusamy, Prema, Srinivasan, Ashokkumar, Ganesan, Thellamudhu, Mangaiah, Suresh, Narasimhan, Kishorekumar, Chakrapani, Lakshmi Narasimhan, J., Thanka, Walter, Charles Emmanuel Jebaraj, Durairajan, Sankari, Nathakattur Saravanabavan, Sanddhya, Periandavan, Kalaiselvi

“…Increased fat consumption in industrialized countries has resulted in hepatic steatosis that upregulates atherogenic aspirant genes, leading to atherosclerosis…”
Get full text

Read Channel Modeling for Detection in Two-Dimensional Magnetic Recording Systems by Krishnan, A.R., Radhakrishnan, R., Vasic, B.

“…In this paper, we describe a read channel model for detector design for two-dimensional magnetic recording (TDMR) system, a novel strategy for recording at…”
Get full text

A comparative study of clinical correlates of bipolar mixed state with bipolar manic and bipolar depressed state in a general hospital psychiatry setting by Raman. Krishnan

Get full text

Preclinical Characterization of BCX9930, a Potent Oral Complement Factor D Inhibitor, Targeting Alternative Pathway-Mediated Diseases Including Paroxysmal Nocturnal Hemoglobinuria (PNH) by Chen, Xilin, Cheng, Xiaogang, Liu, Qingde, Muppa, Saritha, Parker, Cynthia, Zhu, Fugang, Raman, Krishnan, Kotian, Pravin L, Babu, Yarlagadda S.

“…Complement factor D is a serine protease that specifically catalyzes the cleavage of factor B [bound to C3(H2O) or C3b], its only natural substrate, to Ba and…”
Get full text

Effectiveness of a Nurse-Led Intervention for Adolescents With Problematic Internet Use by Mathew, Preeti, Krishnan, Raman, Bhaskar, Adhin

“…The current study assessed the effect of an intervention on problematic internet use (PIU), biopsychosocial functioning, and academic performance in 100…”
Get full text

Berotralstat (BCX7353): Structure-Guided Design of a Potent, Selective, and Oral Plasma Kallikrein Inhibitor to Prevent Attacks of Hereditary Angioedema (HAE) by Kotian, Pravin L, Wu, Minwan, Vadlakonda, Satish, Chintareddy, Venkat, Lu, Pengcheng, Juarez, Luis, Kellogg-Yelder, Debra, Chen, Xilin, Muppa, Saritha, Chambers-Wilson, Ramanda, Davis Parker, Cynthia, Williams, Jason, Polach, Kevin J, Zhang, Weihe, Raman, Krishnan, Babu, Yarlagadda S

“…Hereditary angioedema (HAE) is a rare and potentially life-threatening disease that affects an estimated 1 in 50 000 individuals worldwide. Until recently,…”
Get full text

A rare case modafinil dependence by Krishnan, Raman, Chary, Krishnan Vengadaragava

“…Modafinil, a non-amphetamine psychostimulant, is indicated for narcolepsy, shift work sleep disorder and severe obstructive sleep apnea syndrome. Modafinil is…”
Get full text

Liver Transplantation in Malaysia: Needs, Obstacles, and Opportunities by Khan, Johann F., Shah, Diana Mohd, Sivapakiam, S., Mokhtar, Suryati, Subramaniam, Manisekar, Raman, Krishnan, Singh, Harjit, Pillai, Mohanasundram, Sulaiman, Omar

Get full text

Scaffold hopping via ring opening enables identification of acyclic compounds as new complement Factor D inhibitors by Zhang, Weihe, Wu, Minwan, Vadlakonda, Satish, Juarez, Luis, Cheng, Xiaogang, Muppa, Saritha, Chintareddy, Venkat, Vogeti, Lakshminarayana, Kellogg-Yelder, Debra, Williams, Jason, Polach, Kevin, Chen, Xilin, Raman, Krishnan, Babu, Y.S., Kotian, Pravin

“…[Display omitted] The three complement pathways comprising the early phase of the complement system (the classical, lectin, and alternative pathways) act…”
Get full text