Search Results - "Krishnan, K P"

Targeting a conserved pocket (n-octyl-β-D-glucoside) on the dengue virus envelope protein by small bioactive molecule inhibitors by Naresh, P., Selvaraj, A., Shyam Sundar, P., Murugesan, S., Sathianarayanan, S., Namboori P. K., Krishnan, Jubie, S.

“…Dengue virus enters the cell by receptor-mediated endocytosis followed by a viral envelope (DENVE) protein-mediated membrane fusion. A small detergent molecule…”
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Vitamin D analog calcitriol for breast cancer therapy; an integrated drug discovery approach by B. S., Nagaraj, P. K., Krishnan Namboori, Akey, Krishna Swaroop, Sankaran, Sathianarayanan, Raman, Rajesh Kumar, Natarajan, Jawahar, Selvaraj, Jubie

“…As breast cancer remains leading cause of cancer death globally, it is essential to develop an affordable breast cancer therapy in underdeveloped countries…”
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Abundance and diversity of diazotrophs in the surface sediments of Kongsfjorden, an Arctic fjord by Jabir, T., Vipindas, P. V., Krishnan, K. P., Mohamed Hatha, A. A.

“…Diazotrophy in the Arctic environment is poorly understood compared to tropical and subtropical regions. Hence in this study, we report the abundance and…”
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Bacterial response to dynamic metal concentrations in the surface sediments of a solar saltern (Goa, India) by Pereira, Flory, Kerkar, Savita, Krishnan, K. P.

“…The Ribandar solar saltern, situated adjacent to the Mandovi estuary is influenced by the barge transport of ferromanganese ore to the Mormugao harbour…”
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Leveraging decagonal in-silico strategies for uncovering IL-6 inhibitors with precision by Krishna Swaroop, Akey, Krishnan Namboori, P.K., Esakkimuthukumar, M., Praveen, T.K., Nagarjuna, Palathoti, Patnaik, Sunil Kumar, Selvaraj, Jubie

“…Interleukin-6 upregulation leads to various acute phase reactions such as local inflammation and systemic inflammation in many diseases like cancer, multiple…”
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Tumor Hypoxia Diagnosis using Deep CNN Learning strategy a theranostic pharmacogenomic approach by B, Vaisali, C R, Parvathy, A M, Hima Vyshnavi, P K, Krishnan Namboori

“…Tumor hypoxia results in most of the anticancer drugs becoming ineffective. However, due to lack of proper signaling in the hypoxic micro environment, the…”
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Rate of sediment accumulation and historic metal contamination in a tidewater glacier fjord, Svalbard by Mohan, Mahesh, Sreelakshmi, U., Vishnu Sagar, M.K., Gopikrishna, V.G., Pandit, G.G., Sahu, S.K., Tiwari, M., Ajmal, P.Y., Kannan, V.M., Abdul Shukkur, M., Krishnan, K.P.

“…The sedimentation rates in Arctic fjords are influenced by the changes in the glacial inputs. The recent studies have indicated the retreat of glaciers due to…”
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Organic carbon and iron modulate nitrification rates in mangrove swamps of Goa, south west coast of India by Krishnan, K.P., Loka Bharathi, P.A.

“…Nitrification, fuelled by ammonium is the pivotal oxidative pathway to nitrogen cycling. In spite of its ecological significance, the factors regulating…”
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Bacterial community structure of a glacio-marine system in the Arctic (Ny-Ålesund, Svalbard) by Thomas, Femi Anna, Sinha, Rupesh Kumar, Krishnan, K.P.

“…[Display omitted] •Significant difference in the bacterial diversity of glacio-marine system in Arctic.•MWs exhibited highest diversity index while glacier…”
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In Silico Analysis of the Effect of Hydrastis canadensis on Controlling Breast Cancer by Vyshnavi AM, Hima, Sankaran, Sathianarayanan, Namboori PK, Krishnan, Venkidasamy, Baskar, Hirad, Abdurahman, Alarfaj, Abdullah, Vinayagam, Ramachandran

“…Background and Objectives: Breast cancer is a significant type of cancer among women worldwide. Studies have reported the anti-carcinogenic activity of…”
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Genomic insights into the molecular mechanisms of a Pseudomonas strain significant in its survival in Kongsfjorden, an Arctic fjord by Sinha, Rupesh Kumar, Krishnan, K. P.

“…Whole-genome sequence of Pseudomonas sp. Kongs-67 retrieved from Kongsfjorden, an Arctic fjord, has been investigated to understand the molecular machinery…”
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ApoE gene of Alzheimer's disease (AD) by Namboori, P. K. Krishnan, Vineeth, K. V, Rohith, V, Hassan, Ibnul, Sekhar, Lekshmi, Sekhar, Akhila, Nidheesh, M

“…The ApoE gene responsible for the Alzheimer's disease has been examined to identify functional consequences of single-nucleotide polymorphisms (SNPs)…”
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Phenotypic and molecular identification of Cellulosimicrobium cellulans isolated from Antarctic snow by Antony, Runa, Krishnan, K. P, Thomas, Sabu, Abraham, Wilson Peter, Thamban, M

“…We report for the first time the isolation of Cellulosimicrobium cellulans from Antarctic snow. This strain demonstrated physiological traits that were…”
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Complete genome sequence and comparative genome analysis of Alcanivorax sp. IO_7, a marine alkane-degrading bacterium isolated from hydrothermally-influenced deep seawater of southwest Indian ridge by Sinha, Rupesh Kumar, Krishnan, K.P., Kurian, P. John

“…Genome of Alcanivorax sp. IO_7, an alkane degrading deep-sea bacteria isolated from hydrothermally-influenced Southwest Indian Ridge was sequenced and…”
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Navigating IL-6: From molecular mechanisms to therapeutic breakthroughs by Swaroop, Akey Krishna, Negi, Preeya, Kar, Ayushi, Mariappan, Esakkimuthukumar, Natarajan, Jawahar, Namboori P.K., Krishnan, Selvaraj, Jubie

“…This concise review navigates the intricate realm of Interleukin-6 (IL-6), an important member of the cytokine family. Beginning with an introduction to…”
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Perfluorooctanoic acid in the sediment matrices of Arctic fjords, Svalbard by Saritha, V.K., Krishnan, K.P., Mohan, Mahesh

“…Per- and polyfluorinated chemicals (PFASs) are very toxic industrial compounds, and fewer studies have been conducted on their presence in the sedimentary…”
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Bacterial diversity and their metabolic profiles in the sedimentary environments of Ny-Ålesund, Arctic by Thomas, Femi Anna, Mohan, Mahesh, Krishnan, K. P.

“…Sedimentary environments in the Arctic are known to harbor diverse microbial communities playing a crucial role in the remineralization of organic matter and…”
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Comprehensive strategy for the design of precision drugs and identification of genetic signature behind proneness of the disease—a pharmacogenomic approach by Iyer, Preethi M, Karthikeyan, S, Sanjay Kumar, P, Krishnan Namboori, P K

“…The proneness of diseases and susceptibility towards drugs vary from person to person. At present, there is a strong demand for the personalization of drugs…”
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Phenylobacterium glaciei sp. nov., isolated from Vestrebroggerbreen, a valley glacier in Svalbard, Arctic by Thomas, Femi Anna, Sinha, Rupesh Kumar, Hatha, A A Mohamed, Krishnan, K P

“…A Gram-stain-negative, rod-shaped bacterial strain designated as 20VBR1 was isolated from a valley glacier (Vestrebroggerbreen) snout ice sample from…”
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Dissemination of multidrug resistant bacteria to the polar environment - Role of the longest migratory bird Arctic tern (Sterna paradisaea) by Akhil Prakash, E., Hromádková, Tereza, Jabir, T., Vipindas, P.V., Krishnan, K.P., Mohamed Hatha, A.A., Briedis, Martins

“…The ever-increasing prevalence of antibiotic-resistant bacteria(ARB), primarily due to the frequent use and misuse of antibiotics, is an issue of serious…”
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