Search Results - "Krishnadas, Nandakumar"

COVID-19: Emergence, Spread, Possible Treatments, and Global Burden by Keni, Raghuvir, Alexander, Anila, Nayak, Pawan Ganesh, Mudgal, Jayesh, Nandakumar, Krishnadas

“…The Coronavirus (CoV) is a large family of viruses known to cause illnesses ranging from the common cold to acute respiratory tract infection. The severity of…”
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Sesamol-Loaded PLGA Nanosuspension for Accelerating Wound Healing in Diabetic Foot Ulcer in Rats by Gourishetti, Karthik, Keni, Raghuvir, Nayak, Pawan Ganesh, Jitta, Srinivas Reddy, Bhaskaran, Navya Ajitkumar, Kumar, Lalit, Kumar, Nitesh, Krishnadas, Nandakumar, Shenoy, Rekha Raghuveer

“…Diabetic foot ulcer is an intractable complication of diabetes, characterized by the disturbed inflammatory and proliferative phases of wound healing. Sesamol,…”
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Box–Behnken Design-Based Development and Validation of a Reverse-Phase HPLC Analytical Method for the Estimation of Paclitaxel in Cationic Liposomes by Kumar, Gautam, Mullick, Prashansha, Nandakumar, Krishnadas, Mutalik, Srinivas, Rao, Chamallamudi Mallikarjuna

“…Stability-indicating reverse-phase HPLC analytical method for the quantification of Paclitaxel (PTX) in the bulk and cationic liposomes was developed. The…”
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Investigation of the cellular and molecular effects of dehydrozingerone formulation on various days of diabetic wound repair by Begum, Farmiza, Nandakumar, Krishnadas, Shenoy, Rekha Raghuveer

“…Cases of diabetes are significantly increasing year by year, attracting the attention of medical professionals and researchers to focus on diabetes and its…”
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Jojoba Oil Hastens Dexamethasone Induced Delayed Wound Healing: A Preclinical Study by Begum, Farmiza, Kotian, Pooja J, Hiremath, Snigdha, Ramdasi, Atharva, Sharma, Apoorva, Beegum, Fathima, Gurram, Prasada Chowdhari, Nampoothiri, Madhavan, Krishnadas, Nandakumar, Shenoy, Rekha R

“…Background: Wound healing is a complex, multifactorial process in which poor healing in chronic wounds has emerged as the most significant complication in…”
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An Appraisal of Current Pharmacological Perspectives of Sesamol: A Review by Bosebabu, Bellamkonda, Cheruku, Sri Pragnya, Chamallamudi, Mallikarjuna Rao, Nampoothiri, Madhavan, Shenoy, Rekha R, Nandakumar, Krishnadas, Parihar, Vipan K, Kumar, Nitesh

“…Sesame (Sesamum indicum L.) seeds have been authenticated for its medicinal value in both Chinese and Indian systems of medicine. Its numerous potential…”
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Temozolomide Resistance: A Multifarious Review on Mechanisms Beyond O -6-Methylguanine-DNA Methyltransferase by Rao, Vanishree, Kumar, Gautam, Vibhavari, R J A, Nandakumar, Krishnadas, Thorat, Nanasaheb D, Chamallamudi, Mallikarjuna Rao, Kumar, Nitesh

“…Chemotherapy with the oral alkylating agent temozolomide still prevails as a linchpin in the therapeutic regimen of glioblastoma alongside radiotherapy…”
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Rutin protects against neuronal damage in vitro and ameliorates doxorubicin-induced memory deficits in vivo in Wistar rats by Ramalingayya, Grandhi Venkata, Cheruku, Sri Pragnya, Nayak, Pawan G, Kishore, Anoop, Shenoy, Rekha, Rao, Chamallamudi Mallikarjuna, Krishnadas, Nandakumar

“…Doxorubicin (DOX) is the most widely used broad-spectrum anticancer agent, either alone or in combination, for most cancers including breast cancer. Long-term…”
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Sesamol combats diabetogenic effects of atorvastatin through GLUT-4 expression and improved pancreatic viability by Keni, Raghuvir, Nayak, Pawan Ganesh, Kumar, Nitesh, Kishore, Anoop, Alnasser, Sulaiman Mohammed, Begum, Farmiza, Gourishetti, Karthik, Nandakumar, Krishnadas

“…Statin-associated diabetes (SAD) is an issue that has come to light after a series of recent clinical trials that has led to the issue of a black box warning…”
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Dehydrozingerone promotes healing of diabetic foot ulcers: a molecular insight by Begum, Farmiza, Manandhar, Suman, Kumar, Gautam, Keni, Raghuvir, Sankhe, Runali, Gurram, Prasada Chowdari, Beegum, Fathima, Teja, Meka Sai, Nandakumar, Krishnadas, Shenoy, Rekha R.

“…Introduction One of the most common problems of diabetes are diabetic foot ulcers (DFUs). According to National Institute for Health, initial management of…”
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Beta-Caryophyllene, a CB2R Selective Agonist, Protects Against Cognitive Impairment Caused by Neuro-inflammation and Not in Dementia Due to Ageing Induced by Mitochondrial Dysfunction by Kanojia, Urja, Chaturbhuj, Shrikant Gyaneshwar, Sankhe, Runali, Das, Maushami, Surubhotla, Raviteja, Krishnadas, Nandakumar, Gourishetti, Karthik, Nayak, Pawan Ganesh, Kishore, Anoop

“…Dementia is a neurodegenerative disorder majorly evidenced by cognitive impairment. Although there are many types of dementia, the common underlying…”
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Neuroprotective Effects of Metformin and Berberine in Lipopolysaccharide-Induced Sickness-Like Behaviour in Mice by Kodi, Triveni, Praveen, Sharanya, Paka, Sravan Kumar, Sankhe, Runali, Gopinathan, Adarsh, Krishnadas, Nandakumar, Kishore, Anoop

“…Sickness behaviour, a set of behavioural changes associated with neuroinflammation, is expressed as decreased mobility and depressed behaviour. Activation of…”
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Investigating the role of sesamol in promoting the healing of diabetic wounds by analyzing molecular expression patterns in human diabetic dermal fibroblasts by Beegum, Fathima, P V, Anuranjana, George, Krupa thankam, K P, Divya, Begum, Farmiza, Krishnadas, Nandakumar, Rekha R Shenoy

“…Background: Sesamol (3,4-methylenedioxyphenol) is one of the plant compounds tested in vivo for diabetic wound healing, normal wound healing, and…”
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In-silico and in-vivo evaluation of sesamol and its derivatives for benign prostatic hypertrophy by Shah, Abhishek, Shah, Aarti Abhishek, Nandakumar, Krishnadas, Kumar, Avinash, Pai, Aravinda, Lobo, Richard

“…Pharmacological treatment for BPH includes 5- α reductase inhibitors as Finasteride and Dutasteride as a monotherapy or in combination with antimuscarinic…”
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Restoring chemo-sensitivity to temozolomide via targeted inhibition of poly (ADP-ribose) polymerase-1 by naringin in glioblastoma by Rao, Vanishree, Cheruku, Sri Pragnya, Manandhar, Suman, Vibhavari, R. J. A., Nandakumar, Krishnadas, Rao, C. Mallikarjuna, Ravichandiran, V., Kumar, Nitesh

“…Inclining mortality with a constant plummet in the survival rates associated with glioblastoma still stands as an inveterate predicament. The only promising…”
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Enhancing temozolomide antiglioma response by inhibiting O6-methylguanine-DNA methyltransferase with selected phytochemicals: in silico and in vitro approach by Vibhavari, R. J. A., Rao, Vanishree, Cheruku, Sri Pragnya, Kumar, B. Harish, Maity, Swastika, Nandakumar, Krishnadas, Kumar, Lalit, Mehta, Chetan Hasmukh, Nayak, Usha, Chamallamudi, Mallikarjuna Rao, Kumar, Nitesh

“…The aim of our study was to investigate the potential of rutin, catechin, dehydrozingerone, naringenin, and quercetin, both alone and in combination with…”
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Naringin and Rutin Alleviates Episodic Memory Deficits in Two Differentially Challenged Object Recognition Tasks by Ramalingayya, Grandhi Venkata, Nampoothiri, Madhavan, Nayak, Pawan G, Kishore, Anoop, Shenoy, Rekha R, Mallikarjuna Rao, Chamallamudi, Nandakumar, Krishnadas

“…Cognitive decline or dementia is a debilitating problem of neurological disorders such as Alzheimer's and Parkinson's disease, including special conditions…”
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Sesamol protects MIN6 pancreatic beta cells against simvastatin-induced toxicity by restoring mitochondrial membrane potentials by Ghadge, Girish A., Gourishetti, Karthik, Chamallamudi, Mallikarjuna Rao, Nampurath, Gopalan Kutty, Nandakumar, Krishnadas, Kumar, Nitesh

“…Statins, the drugs for the treatment of dyslipidemia, have been suggested to impact insulin sensitivity, resulting in pancreatic β-cell dysfunction, and…”
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Anticonvulsant activity of fraction isolated from ethanolic extract of heartwood of Cedrus deodara by Dhayabaran, Daniel, Florance, Ebinezar Jeyaseeli, Nandakumar, Krishnadas, Shanmugarathinam, Alagarsamy, Puratchikody, Ayarivan

“…The heartwood of Cedrus deodara is traditionally used for the treatment of neurological disorders in India. In this study, the compound…”
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Botrops derived hemocoagulase formulation a probable agent for diabetic wound healing by Keni, Raghuvir, Gourishetti, Karthik, Kinra, Manas, Nayak, Pawan G., Shenoy, Rekha, Nandakumar, Krishnadas, Jagdale, Rajesh N., Raghavendra, K. V., Ahmed, Syed Mushtaq

“…Botroclot is a marketed preparation containing hemocoagulase, which is an enzyme having coagulant activity, isolated from the snake Botrops atrox. This…”
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