Search Results - "Krieger, Stèphanie"

Immune System Dysregulation During Spaceflight: Potential Countermeasures for Deep Space Exploration Missions by Crucian, Brian E, Choukèr, Alexander, Simpson, Richard J, Mehta, Satish, Marshall, Gailen, Smith, Scott M, Zwart, Sara R, Heer, Martina, Ponomarev, Sergey, Whitmire, Alexandra, Frippiat, Jean P, Douglas, Grace L, Lorenzi, Hernan, Buchheim, Judith-Irina, Makedonas, George, Ginsburg, Geoffrey S, Ott, C Mark, Pierson, Duane L, Krieger, Stephanie S, Baecker, Natalie, Sams, Clarence

“…Recent studies have established that dysregulation of the human immune system and the reactivation of latent herpesviruses persists for the duration of a…”
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Alterations in Saliva and Plasma Cytokine Concentrations During Long-Duration Spaceflight by Krieger, Stephanie S, Zwart, Sara R, Mehta, Satish, Wu, Honglu, Simpson, Richard J, Smith, Scott M, Crucian, Brian

“…Long-duration spaceflight is known to cause immune dysregulation in astronauts. Biomarkers of immune system function are needed to determine both the need for…”
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Arterial structure and function during and after long-duration spaceflight by Lee, Stuart M C, Ribeiro, L Christine, Martin, David S, Zwart, Sara R, Feiveson, Alan H, Laurie, Steven S, Macias, Brandon R, Crucian, Brian E, Krieger, Stephanie, Weber, Daniela, Grune, Tilman, Platts, Steven H, Smith, Scott M, Stenger, Michael B

“…Spaceflight missions expose astronauts to increased risk of oxidative stress and inflammatory damage that might accelerate the development of asymptomatic…”
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Specific Immunologic Countermeasure Protocol for Deep-Space Exploration Missions by Makedonas, George, Mehta, Satish, Choukèr, Alexander, Simpson, Richard J, Marshall, Gailen, Orange, Jordan S, Aunon-Chancellor, Serena, Smith, Scott M, Zwart, Sara R, Stowe, Raymond P, Heer, Martina, Ponomarev, Sergey, Whitmire, Alexandra, Frippiat, Jean P, Douglas, Grace L, Krieger, Stephanie S, Lorenzi, Hernan, Buchheim, Judith-Irina, Ginsburg, Geoffrey S, Ott, C Mark, Downs, Meghan, Pierson, Duane, Baecker, Natalie, Sams, Clarence, Crucian, Brian

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SIRT2 Deacetylates and Inhibits the Peroxidase Activity of Peroxiredoxin-1 to Sensitize Breast Cancer Cells to Oxidant Stress-Inducing Agents by Fiskus, Warren, Coothankandaswamy, Veena, Chen, Jianguang, Ma, Hongwei, Ha, Kyungsoo, Saenz, Dyana T, Krieger, Stephanie S, Mill, Christopher P, Sun, Baohua, Huang, Peng, Mumm, Jeffrey S, Melnick, Ari M, Bhalla, Kapil N

“…SIRT2 is a protein deacetylase with tumor suppressor activity in breast and liver tumors where it is mutated; however, the critical substrates mediating its…”
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Synergistic activity of BET protein antagonist-based combinations in mantle cell lymphoma cells sensitive or resistant to ibrutinib by Sun, Baohua, Shah, Bhavin, Fiskus, Warren, Qi, Jun, Rajapakshe, Kimal, Coarfa, Cristian, Li, Li, Devaraj, Santhana G.T., Sharma, Sunil, Zhang, Liang, Wang, Michael L., Saenz, Dyana T., Krieger, Stephanie, Bradner, James E., Bhalla, Kapil N.

“…Mantle cell lymphoma (MCL) cells exhibit increased B-cell receptor and nuclear factor (NF)-κB activities. The bromodomain and extra-terminal (BET) protein…”
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Dermatitis during Spaceflight Associated with HSV-1 Reactivation by Mehta, Satish K., Szpara, Moriah L., Rooney, Bridgette, Diak, Douglass M., Shipley, Mackenzie M., Renner, Daniel W., Krieger, Stephanie S., Zwart, Sara R., Smith, Scott M., Crucian, Brian E.

“…Human alpha herpesviruses herpes simplex virus (HSV-1) and varicella zoster virus (VZV) establish latency in various cranial nerve ganglia and often reactivate…”
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Estrutura Interna da Escala Cognitiva de Ansiedade (ECOGA) by Baptista, Makilim Nunes, Falcone, Eliane Mary de Oliveira, Viegas, Monique Placido, Oliveira, Evlyn Rodrigues, Krieger, Stèphanie, Pereira, Luisa Braga, Alves, Ana Júlia de Carvalho Pereira, Peluso, Marcelo Leonel, Silva, Filipe Tomé da

“…Resumo Este estudo objetivou investigar evidências de validade de estrutura interna para a Escala Cognitiva de Ansiedade (ECOGA) por análise fatorial…”
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Integration of the Food Supply Chain as a Driver of Sustainability: A Conceptual Framework by Bezat-Jarzębowska, Agnieszka, Krieger-Güss, Stephanie, Jarzębowski, Sebastian, Petersen, Brigitte

“…This paper presents a conceptual framework aimed at exploring the connections between integration within the food supply chain and the three pillars of…”
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Short-term isolation effects on the brain, cognitive performance, and sleep-The role of exercise by Klein, Timo, Braunsmann, Leonard, Koschate, Jessica, Hoffmann, Uwe, Foitschik, Tina, Krieger, Stephanie, Crucian, Brian, Schneider, Stefan, Abeln, Vera

“…Isolation is stressful and negatively affects sleep and mood and might also affect the structure and function of the brain. Physical exercise improves brain…”
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Transcriptomics, NF-κB Pathway, and Their Potential Spaceflight-Related Health Consequences by Zhang, Ye, Moreno-Villanueva, Maria, Krieger, Stephanie, Ramesh, Govindarajan T, Neelam, Srujana, Wu, Honglu

“…In space, living organisms are exposed to multiple stress factors including microgravity and space radiation. For humans, these harmful environmental factors…”
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Impact of diet on human nutrition, immune response, gut microbiome, and cognition in an isolated and confined mission environment by Douglas, Grace L., DeKerlegand, Diane, Dlouhy, Holly, Dumont-Leblond, Nathan, Fields, Eden, Heer, Martina, Krieger, Stephanie, Mehta, Satish, Rooney, Bridgette V., Torralba, Manolito G., Whiting, Sara E., Crucian, Brian, Lorenzi, Hernan, Smith, Scott M., Young, Millennia, Zwart, Sara R.

“…Long-duration spaceflight impacts human physiology, including well documented immune system dysregulation. The space food system has the potential to serve as…”
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DNA Damage and Radiosensitivity in Blood Cells from Subjects Undergoing 45 Days of Isolation and Confinement: An Explorative Study by Feiveson, Alan H., Krieger, Stephanie S., von Scheven, Gudrun, Crucian, Brian E., Bürkle, Alexander, Stahn, Alexander C., Wu, Honglu, Moreno-Villanueva, María

“…The effect of confined and isolated experience on astronauts’ health is an important factor to consider for future space exploration missions. The more…”
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Cross-inhibition of NMBR and GRPR signaling maintains normal histaminergic itch transmission by Zhao, Zhong-Qiu, Wan, Li, Liu, Xian-Yu, Huo, Fu-Quan, Li, Hui, Barry, Devin M, Krieger, Stephanie, Kim, Seungil, Liu, Zhong-Chun, Xu, Jinbin, Rogers, Buck E, Li, Yun-Qing, Chen, Zhou-Feng

“…We previously showed that gastrin-releasing peptide receptor (GRPR) in the spinal cord is important for mediating nonhistaminergic itch. Neuromedin B receptor…”
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Synergistic Effects of Weightlessness, Isoproterenol, and Radiation on DNA Damage Response and Cytokine Production in Immune Cells by Moreno-Villanueva, Maria, Feiveson, Alan H, Krieger, Stephanie, Kay Brinda, AnneMarie, von Scheven, Gudrun, Bürkle, Alexander, Crucian, Brian, Wu, Honglu

“…The implementation of rotating-wall vessels (RWVs) for studying the effect of lack of gravity has attracted attention, especially in the fields of stem cells,…”
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Single-Cell RNA-Sequencing Identifies Activation of TP53 and STAT1 Pathways in Human T Lymphocyte Subpopulations in Response to Ex Vivo Radiation Exposure by Moreno-Villanueva, Maria, Zhang, Ye, Feiveson, Alan, Mistretta, Brandon, Pan, Yinghong, Chatterjee, Sujash, Wu, Winston, Clanton, Ryan, Nelman-Gonzalez, Mayra, Krieger, Stephanie, Gunaratne, Preethi, Crucian, Brian, Wu, Honglu

“…Detrimental health consequences from exposure to space radiation are a major concern for long-duration human exploration missions to the Moon or Mars. Cellular…”
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Countermeasures-based Improvements in Stress, Immune System Dysregulation and Latent Herpesvirus Reactivation onboard the International Space Station – Relevance for Deep Space Missions and Terrestrial Medicine by Crucian, Brian E., Makedonas, George, Sams, Clarence F., Pierson, Duane L., Simpson, Richard, Stowe, Raymond P., Smith, Scott M., Zwart, Sara R., Krieger, Stephanie S., Rooney, Bridgette, Douglas, Grace, Downs, Meghan, Nelman-Gonzalez, Mayra, Williams, Thomas J., Mehta, Satish

“…•Orbital spaceflight induces immune alterations consisting of reductions in T, NK cell function, elevated salivary stress hormones and the persistent…”
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Synthesis and radiopharmacological evaluation of a high-affinity and metabolically stabilized 18F-labeled bombesin analogue for molecular imaging of gastrin-releasing peptide receptor-expressing prostate cancer by Richter, Susan, Wuest, Melinda, Krieger, Stephanie S., Rogers, Buck E., Friebe, Matthias, Bergmann, Ralf, Wuest, Frank

“…Bombesin (BBN) and BBN analogues have attracted much attention as high-affinity ligands for selective targeting of the gastrin-releasing peptide (GRP)…”
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Monitoring of Biodistribution and Persistence of Conditionally Replicative Adenovirus in a Murine Model of Ovarian Cancer Using Capsid-Incorporated mCherry and Expression of Human Somatostatin Receptor Subtype 2 Gene by Dmitriev, Igor P., Kashentseva, Elena A., Kim, Kenneth H., Matthews, Qiana L., Krieger, Stephanie S., Parry, Jesse J., Nguyen, Kim N., Akers, Walter J., Achilefu, Samuel, Rogers, Buck E., Alvarez, Ronald D., Curiel, David T.

“…A significant limiting factor to the human clinical application of conditionally replicative adenovirus (CRAd)-based virotherapy is the inability to…”
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Validade convergente do Inventário de Empatia (IE) by Eliane Mary de Oliveira Falcone, Vanessa Dordron de Pinho, Ferreira, Maria Cristina, Conceição dos Santos Fernandes, Juliana Furtado D'Augustin, Krieger, Stèphanie, Monique Gomes Plácido, Keyth de Oliveira Vianna, Lucimar da Costa Torres Electo, Layse Costa Pinheiro

“…O estudo teve como objetivo investigar a validade convergente do Inventário de Empatia. A amostra foi composta por 230 indivíduos adultos, de ambos os sexos,…”
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