Search Results - "Krieger, C C"

Delayed diagnosis of narcolepsy: characterization and impact by Thorpy, Michael J, Krieger, Ana C

“…Highlights • Narcolepsy is a chronic neurologic condition, which frequently has an early onset. • A long delay until diagnosis has been consistently reported…”
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Mutation of the Human Circadian Clock Gene CRY1 in Familial Delayed Sleep Phase Disorder by Patke, Alina, Murphy, Patricia J., Onat, Onur Emre, Krieger, Ana C., Özçelik, Tayfun, Campbell, Scott S., Young, Michael W.

“…Patterns of daily human activity are controlled by an intrinsic circadian clock that promotes ∼24 hr rhythms in many behavioral and physiological processes…”
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TSH/IGF1 receptor crosstalk: Mechanism and clinical implications by Krieger, Christine C., Neumann, Susanne, Gershengorn, Marvin C.

“…Increasing evidence of interdependence between G protein-coupled receptors and receptor tyrosine kinase signaling pathways has prompted reevaluation of…”
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TSH/IGF-1 Receptor Cross Talk in Graves' Ophthalmopathy Pathogenesis by Krieger, Christine C, Place, Robert F, Bevilacqua, Carmine, Marcus-Samuels, Bernice, Abel, Brent S, Skarulis, Monica C, Kahaly, George J, Neumann, Susanne, Gershengorn, Marvin C

“…Context: The TSH receptor (TSHR) is considered the main target of stimulatory autoantibodies in the pathogenesis of Graves' ophthalmopathy (GO); however, it…”
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Inhibition of TSH/IGF-1 Receptor Crosstalk by Teprotumumab as a Treatment Modality of Thyroid Eye Disease by Krieger, Christine C, Sui, Xiangliang, Kahaly, George J, Neumann, Susanne, Gershengorn, Marvin C

“…We previously presented evidence that TSH receptor (TSHR)-stimulating autoantibodies (TSAbs) bind to and activate TSHRs but do not bind to IGF1 receptors…”
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Future Prospects for the Treatment of Graves' Hyperthyroidism and Eye Disease by Neumann, S, Place, R F, Krieger, C C, Gershengorn, M C

“…Although there are adequate therapies for Graves' hyperthyroidism, mild to moderate Graves' orbitopathy (GO) is usually treated symptomatically whereas…”
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A GridPix-based X-ray detector for the CAST experiment by Krieger, C., Kaminski, J., Lupberger, M., Desch, K.

“…The CAST experiment has been searching for axions and axion-like particles for more than 10 years. The continuous improvements in the detector designs have…”
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Validity of self-reported sleep bruxism among myofascial temporomandibular disorder patients and controls by Raphael, K. G., Janal, M. N., Sirois, D. A., Dubrovsky, B., Klausner, J. J., Krieger, A. C., Lavigne, G. J.

“…Summary Sleep bruxism (SB), primarily involving rhythmic grinding of the teeth during sleep, has been advanced as a causal or maintenance factor for a variety…”
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COVID-19 will change MS care forever – Commentary by Krieger, SC

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Is There Evidence for IGF1R-Stimulating Abs in Graves' Orbitopathy Pathogenesis? by Krieger, Christine C, Neumann, Susanne, Gershengorn, Marvin C

“…In this review, we summarize the evidence against direct stimulation of insulin-like growth factor 1 receptors (IGF1Rs) by autoantibodies in Graves'…”
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Detection of subtle gait disturbance and future fall risk in early multiple sclerosis by Brandstadter, Rachel, Ayeni, Oluwasheyi, Krieger, Stephen C., Harel, Noam Y., Escalon, Miguel X., Katz Sand, Ilana, Leavitt, Victoria M., Fabian, Michelle T., Buyukturkoglu, Korhan, Klineova, Sylvia, Riley, Claire S., Lublin, Fred D., Miller, Aaron E., Sumowski, James F.

“…OBJECTIVETo test the hypothesis that higher-challenge gait and balance tasks are more sensitive than traditional metrics to subtle patient-reported gait…”
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Deduced Respiratory Scores on COVID-19 Patients Learning from Exertion-Induced Dyspnea by Zhang, Zijing, Zhou, Jianlin, Conroy, Thomas B, Chung, Samuel, Choi, Justin, Chau, Patrick, Green, Daniel B, Krieger, Ana C, Kan, Edwin C

“…Dyspnea is one of the most common symptoms of many respiratory diseases, including COVID-19. Clinical assessment of dyspnea relies mainly on self-reporting,…”
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Proximity ligation assay to study TSH receptor homodimerization and crosstalk with IGF-1 receptors in human thyroid cells by Krieger, Christine C., Boutin, Alisa, Neumann, Susanne, Gershengorn, Marvin C.

“…Proximity ligation assay (PLA) is a methodology that permits detection of protein-protein closeness, that is, proteins that are within 40 nanometers of each…”
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Sleep bruxism and myofascial temporomandibular disorders A laboratory-based polysomnographic investigation by Raphael, Karen G, Sirois, David A, Janal, Malvin N, Wigren, Pia E, Dubrovsky, Boris, Nemelivsky, Lena V, Klausner, Jack J, Krieger, Ana C, Lavigne, Gilles J

“…Many dentists believe that sleep bruxism (SB) is a pathogenic factor in myofascial temporomandibular disorder (TMD), but almost all supportive data rely on…”
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A systematic review of non-pharmacological interventions to improve nighttime sleep among residents of long-term care settings by Capezuti, Elizabeth, Sagha Zadeh, Rana, Pain, Kevin, Basara, Aleksa, Jiang, Nancy Ziyan, Krieger, Ana C

“…Disturbances in sleep and circadian rhythms are common among residents of long-term care facilities. In this systematic review, we aim to identify and evaluate…”
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InGrid-based X-ray detector for low background searches by Krieger, C., Kaminski, J., Desch, K.

“…An X-ray photon detector based on the highly granular readout of an InGrid is described. This gaseous detector, based on a highly pixelized readout chip with…”
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Targeting TSH and IGF-1 Receptors to Treat Thyroid Eye Disease by Neumann, Susanne, Krieger, Christine C., Gershengorn, Marvin C.

“…Graves’ disease (GD) is an autoimmune disease caused in part by thyroid-stimulating antibodies (TSAbs) that activate the thyroid-stimulating hormone receptor…”
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TSH Receptor Homodimerization in Regulation of cAMP Production in Human Thyrocytes in vitro by Boutin, Alisa, Krieger, Christine C, Marcus-Samuels, Bernice, Klubo-Gwiezdzinska, Joanna, Neumann, Susanne, Gershengorn, Marvin C

“…Thyrotropin hormone (TSH) was reported to exhibit biphasic regulation of cAMP production in human thyroid slices; specifically, upregulation at low TSH doses…”
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Masticatory muscle sleep background electromyographic activity is elevated in myofascial temporomandibular disorder patients by Raphael, K. G., Janal, M. N., Sirois, D. A., Dubrovsky, B., Wigren, P. E., Klausner, J. J., Krieger, A. C., Lavigne, G. J.

“…Summary Despite theoretical speculation and strong clinical belief, recent research using laboratory polysomnographic (PSG) recording has provided new evidence…”
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Autonomic dysfunction in isolated rapid eye movement sleep without atonia by Barone, Daniel A, Ebben, Matthew R, Samie, Ashkan, Mortara, David, Krieger, Ana C

“…Highlights • Isolated REM sleep without atonia (RSWA) is of unclear clinical significance. • We demonstrate a significant reduction in several parameters of…”
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