Search Results - "Krieg, Paul A."

Student engagement, assessed using heart rate, shows no reset following active learning sessions in lectures by Darnell, Diana K, Krieg, Paul A

“…Heart rate can be used as a measure of cognitive engagement. We measured average student heart rates during medical school lecture classes using…”
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A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function by Cahoy, John D, Emery, Ben, Kaushal, Amit, Foo, Lynette C, Zamanian, Jennifer L, Christopherson, Karen S, Xing, Yi, Lubischer, Jane L, Krieg, Paul A, Krupenko, Sergey A, Thompson, Wesley J, Barres, Ben A

“…Understanding the cell-cell interactions that control CNS development and function has long been limited by the lack of methods to cleanly separate neural cell…”
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Combinatorial Regulation of Endothelial Gene Expression by Ets and Forkhead Transcription Factors by De Val, Sarah, Chi, Neil C., Meadows, Stryder M., Minovitsky, Simon, Anderson, Joshua P., Harris, Ian S., Ehlers, Melissa L., Agarwal, Pooja, Visel, Axel, Xu, Shan-Mei, Pennacchio, Len A., Dubchak, Inna, Krieg, Paul A., Stainier, Didier Y.R., Black, Brian L.

“…Vascular development begins when mesodermal cells differentiate into endothelial cells, which then form primitive vessels. It has been hypothesized that…”
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Nebulin regulates actin filament lengths by a stabilization mechanism by Pappas, Christopher T, Krieg, Paul A, Gregorio, Carol C

“…Efficient muscle contraction requires regulation of actin filament lengths. In one highly cited model, the giant protein nebulin has been proposed to function…”
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Regulation of endothelial cell development by ETS transcription factors by Meadows, Stryder M., Myers, Candace T., Krieg, Paul A.

“…The ETS family of transcription factors plays an essential role in controlling endothelial gene expression. Multiple members of the ETS family are expressed in…”
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Apelin, the ligand for the endothelial G-protein-coupled receptor, APJ, is a potent angiogenic factor required for normal vascular development of the frog embryo by Cox, Christopher M., D'Agostino, Susan L., Miller, Melanie K., Heimark, Ronald L., Krieg, Paul A.

“…The peptide growth factor apelin is the high affinity ligand for the G-protein-coupled receptor APJ. During embryonic development of mouse and frog, APJ…”
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Leiomodin 3 and tropomodulin 4 have overlapping functions during skeletal myofibrillogenesis by Nworu, Chinedu U, Kraft, Robert, Schnurr, Daniel C, Gregorio, Carol C, Krieg, Paul A

“…Precise regulation of thin filament length is essential for optimal force generation during muscle contraction. The thin filament capping protein tropomodulin…”
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Sfrp5 coordinates foregut specification and morphogenesis by antagonizing both canonical and noncanonical Wnt11 signaling by Li, Yan, Rankin, Scott A, Sinner, Débora, Kenny, Alan P, Krieg, Paul A, Zorn, Aaron M

“…Cell identity and tissue morphogenesis are tightly orchestrated during organogenesis, but the mechanisms regulating this are poorly understood. We show that…”
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Non-canonical Wnt signaling through Wnt5a/b and a novel Wnt11 gene, Wnt11b, regulates cell migration during avian gastrulation by Hardy, Katharine M., Garriock, Robert J., Yatskievych, Tatiana A., D'Agostino, Susan L., Antin, Parker B., Krieg, Paul A.

“…Knowledge of the molecular mechanisms regulating cell ingression, epithelial–mesenchymal transition and migration movements during amniote gastrulation is…”
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Census of vertebrate Wnt genes: Isolation and developmental expression of Xenopus Wnt2, Wnt3, Wnt9a, Wnt9b, Wnt10a, and Wnt16 by Garriock, Robert J., Warkman, Andrew S., Meadows, Stryder M., D'Agostino, Susan, Krieg, Paul A.

“…The Wnt family of growth factors regulate many different aspects of embryonic development. Assembly of the complete mouse and human genome sequences, plus…”
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Hedgehog signaling is essential for endothelial tube formation during vasculogenesis by Vokes, Steven A, Yatskievych, Tatiana A, Heimark, Ronald L, McMahon, Jill, McMahon, Andrew P, Antin, Parker B, Krieg, Paul A

“…During embryonic development, the first blood vessels are formed through the aggregation and subsequent assembly of angioblasts (endothelial precursors) into a…”
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Developmental expression and cardiac transcriptional regulation of Myh7b, a third myosin heavy chain in the vertebrate heart by Warkman, Andrew S., Whitman, Samantha A., Miller, Melanie K., Garriock, Robert J., Schwach, Catherine M., Gregorio, Carol C., Krieg, Paul A.

“…The mammalian heart expresses two myosin heavy chain (MYH) genes (Myh6 and Myh7), which are major components of the thick filaments of the sarcomere. We have…”
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Wnt11-R, a protein closely related to mammalian Wnt11, is required for heart morphogenesis in Xenopus by Garriock, Robert J., D'Agostino, Susan L., Pilcher, Karen C., Krieg, Paul A.

“…Wnt11 is a secreted protein that signals through the non-canonical planar cell polarity pathway and is a potent modulator of cell behavior and movement. In…”
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Hedgehog signaling regulates size of the dorsal aortae and density of the plexus during avian vascular development by Moran, Carlos M., Salanga, Matthew C., Krieg, Paul A.

“…Signaling by the hedgehog (Hh) family of secreted growth factors is essential for development of embryonic blood vessels. Embryos lacking Hh function have…”
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Transgenic analysis of the atrialnatriuretic factor (ANF) promoter: Nkx2-5 and GATA-4 binding sites are required for atrial specific expression of ANF by Small, Eric M, Krieg, Paul A

“…The atrial natriuretic factor (ANF) gene is initially expressed throughout the myocardial layer of the heart, but during subsequent development, expression…”
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Myocardin is sufficient and necessary for cardiac gene expression in Xenopus by Small, Eric M, Warkman, Andrew S, Wang, Da-Zhi, Sutherland, Lillian B, Olson, Eric N, Krieg, Paul A

“…Myocardin is a cardiac- and smooth muscle-specific cofactor for the ubiquitous transcription factor serum response factor (SRF). Using gain-of-function…”
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Molecular Regulation of Cardiac Chamber-Specific Gene Expression by Small, Eric M, Krieg, Paul A

“…This review focuses on recent studies investigating the genetic regulatory mechanisms leading to formation of morphologically, functionally, and molecularly…”
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myocardin-related transcription factor, MASTR, cooperates with MyoD to activate skeletal muscle gene expression by Meadows, Stryder M, Warkman, Andrew S, Salanga, Matthew C, Small, Eric M, Krieg, Paul A

“…The myocardin family proteins (myocardin, MRTF-A, and MRTF-B) are serum response factor (SRF) cofactors and potent transcription activators. Gene-ablation…”
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Endoderm is required for vascular endothelial tube formation, but not for angioblast specification by Vokes, Steven A, Krieg, Paul A

“…Angioblasts, the precursor cells that comprise the endothelial layer of blood vessels, arise from a purely mesodermal population. Individual angioblasts…”
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Reagents for developmental regulation of Hedgehog signaling by Lewis, Cristy, Krieg, Paul A.

“…•An inducible Gli1 construction activates Hh signaling.•Cyclopamine effectively inhibits Hh signaling in late stage Xenopus embryos.•SAG and PMA are effective…”
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