Search Results - "Križančić Bombek, Lidija"

Protective Role of Mitochondrial Uncoupling Proteins against Age-Related Oxidative Stress in Type 2 Diabetes Mellitus by Čater, Maša, Bombek, Lidija Križančić

“…The accumulation of oxidative damage to DNA and other biomolecules plays an important role in the etiology of aging and age-related diseases such as type 2…”
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Pathophysiology of exercise-induced muscle damage and its structural, functional, metabolic, and clinical consequences by Stožer, A, Vodopivc, P, Križančić Bombek, L

“…Extreme or unaccustomed eccentric exercise can cause exercise-induced muscle damage, characterized by structural changes involving sarcomere, cytoskeletal, and…”
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NMDA receptor inhibition increases, synchronizes, and stabilizes the collective pancreatic beta cell activity: Insights through multilayer network analysis by Šterk, Marko, Križančić Bombek, Lidija, Skelin Klemen, Maša, Slak Rupnik, Marjan, Marhl, Marko, Stožer, Andraž, Gosak, Marko

“…NMDA receptors promote repolarization in pancreatic beta cells and thereby reduce glucose-stimulated insulin secretion. Therefore, NMDA receptors are a…”
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Skeletal Muscle Uncoupling Proteins in Mice Models of Obesity by Bombek, Lidija Križančić, Čater, Maša

“…Obesity and accompanying type 2 diabetes are among major and increasing worldwide problems that occur fundamentally due to excessive energy intake during its…”
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The Role of cAMP in Beta Cell Stimulus-Secretion and Intercellular Coupling by Stožer, Andraž, Paradiž Leitgeb, Eva, Pohorec, Viljem, Dolenšek, Jurij, Križančić Bombek, Lidija, Gosak, Marko, Skelin Klemen, Maša

“…Pancreatic beta cells secrete insulin in response to stimulation with glucose and other nutrients, and impaired insulin secretion plays a central role in…”
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Glucose-Stimulated Calcium Dynamics in Beta Cells From Male C57BL/6J, C57BL/6N, and NMRI Mice: A Comparison of Activation, Activity, and Deactivation Properties in Tissue Slices by Pohorec, Viljem, Križančić Bombek, Lidija, Skelin Klemen, Maša, Dolenšek, Jurij, Stožer, Andraž

“…Although mice are a very instrumental model in islet beta cell research, possible phenotypic differences between strains and substrains are largely neglected…”
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From Isles of Königsberg to Islets of Langerhans: Examining the Function of the Endocrine Pancreas Through Network Science by Stožer, Andraž, Šterk, Marko, Paradiž Leitgeb, Eva, Markovič, Rene, Skelin Klemen, Maša, Ellis, Cara E, Križančić Bombek, Lidija, Dolenšek, Jurij, MacDonald, Patrick E, Gosak, Marko

“…Islets of Langerhans are multicellular microorgans located in the pancreas that play a central role in whole-body energy homeostasis. Through secretion of…”
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The effect of forskolin and the role of Epac2A during activation, activity, and deactivation of beta cell networks by Skelin Klemen, Maša, Dolenšek, Jurij, Križančić Bombek, Lidija, Pohorec, Viljem, Gosak, Marko, Slak Rupnik, Marjan, Stožer, Andraž

“…Beta cells couple stimulation by glucose with insulin secretion and impairments in this coupling play a central role in diabetes mellitus. Cyclic adenosine…”
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Assessing the origin and velocity of Ca2+ waves in three-dimensional tissue: Insights from a mathematical model and confocal imaging in mouse pancreas tissue slices by Šterk, Marko, Dolenšek, Jurij, Bombek, Lidija Križančić, Markovič, Rene, Zakelšek, Darko, Perc, Matjaž, Pohorec, Viljem, Stožer, Andraž, Gosak, Marko

“…•Intercellular Ca2+ waves coordinate the function of multicellular systems.•Determining the origin and velocity of Ca2+ waves in 3D tissue is challenging.•We…”
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Exendin-4 affects calcium signalling predominantly during activation and activity of beta cell networks in acute mouse pancreas tissue slices by Paradiž Leitgeb, Eva, Kerčmar, Jasmina, Križančić Bombek, Lidija, Pohorec, Vilijem, Skelin Klemen, Maša, Slak Rupnik, Marjan, Gosak, Marko, Dolenšek, Jurij, Stožer, Andraž

“…Tight control of beta cell stimulus-secretion coupling is crucial for maintaining homeostasis of energy-rich nutrients. While glucose serves as a primary…”
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Physiological levels of adrenaline fail to stop pancreatic beta cell activity at unphysiologically high glucose levels by Sluga, Nastja, Križančić Bombek, Lidija, Kerčmar, Jasmina, Sarikas, Srdjan, Postić, Sandra, Pfabe, Johannes, Skelin Klemen, Maša, Korošak, Dean, Stožer, Andraž, Slak Rupnik, Marjan

“…Adrenaline inhibits insulin secretion from pancreatic beta cells to allow an organism to cover immediate energy needs by unlocking internal nutrient reserves…”
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SNAP-25b-deficiency increases insulin secretion and changes spatiotemporal profile of Ca2+oscillations in β cell networks by Daraio, Teresa, Bombek, Lidija Križančić, Gosak, Marko, Valladolid-Acebes, Ismael, Klemen, Maša Skelin, Refai, Essam, Berggren, Per-Olof, Brismar, Kerstin, Rupnik, Marjan Slak, Bark, Christina

“…SNAP-25 is a protein of the core SNARE complex mediating stimulus-dependent release of insulin from pancreatic β cells. The protein exists as two alternatively…”
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Aspects of the progesterone response in Hortaea werneckii: Steroid detoxification, protein induction and remodelling of the cell wall by Križančić Bombek, Lidija, Lapornik, Ajda, Ukmar, Marjeta, Matis, Maja, Črešnar, Bronislava, Katalinić, Jasna Peter, Žakelj-Mavrič, Marija

“…Progesterone in sublethal concentrations temporarily inhibits growth of Hortaea werneckii. This study investigates some of the compensatory mechanisms which…”
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How safe is germinal vesicle stage oocyte rescue? Aneuploidy analysis of in vitro matured oocytes by Vlaisavljević, Veljko, Križančić Bombek, Lidija, Vokač, Nadja Kokalj, Kovačič, Borut, Čižek-Sajko, Mojca

“…Abstract Objective To evaluate the rate and type of aneuploidies of chromosomes 13, 16, 18, 21 and 22, with respect to the length of in vitro maturation (IVM)…”
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Functional characteristics of hub and wave-initiator cells in β cell networks by Šterk, Marko, Dolenšek, Jurij, Skelin Klemen, Maša, Križančić Bombek, Lidija, Paradiž Leitgeb, Eva, Kerčmar, Jasmina, Perc, Matjaž, Slak Rupnik, Marjan, Stožer, Andraž, Gosak, Marko

“…Islets of Langerhans operate as multicellular networks in which several hundred β cells work in synchrony to produce secretory pulses of insulin, a hormone…”
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High-resolution analysis of the cytosolic Ca 2+ events in β cell collectives in situ by Postić, Sandra, Sarikas, Srdjan, Pfabe, Johannes, Pohorec, Viljem, Križančić Bombek, Lidija, Sluga, Nastja, Skelin Klemen, Maša, Dolenšek, Jurij, Korošak, Dean, Stožer, Andraž, Evans-Molina, Carmella, Johnson, James D, Slak Rupnik, Marjan

“…The release of peptide hormones is predominantly regulated by a transient increase in cytosolic Ca concentration ([Ca ] ). To trigger exocytosis, Ca ions enter…”
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Calcium Imaging and Analysis in Beta Cells in Acute Mouse Pancreas Tissue Slices by Paradiž Leitgeb, Eva, Pohorec, Viljem, Križančić Bombek, Lidija, Skelin Klemen, Maša, Duh, Maja, Gosak, Marko, Dolenšek, Jurij, Stožer, Andraž

“…Ca ions play a central role in the stimulus-secretion coupling cascade of pancreatic beta cells. The use of confocal microscopy in conjunction with the acute…”
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SNAP-25b-deficiency increases insulin secretion and changes spatiotemporal profile of Ca 2+ oscillations in β cell networks by Daraio, Teresa, Bombek, Lidija Križančić, Gosak, Marko, Valladolid-Acebes, Ismael, Klemen, Maša Skelin, Refai, Essam, Berggren, Per-Olof, Brismar, Kerstin, Rupnik, Marjan Slak, Bark, Christina

“…SNAP-25 is a protein of the core SNARE complex mediating stimulus-dependent release of insulin from pancreatic β cells. The protein exists as two alternatively…”
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The influence of zygote pronuclear morphology on in vitro human embryo development by Lidija Križančić-Bombek, Veljko Vlaisavljević

“…Background: The selection of embryos with largest implantation potential is an important part in assisted reproduction. Besides the embryo or blastocyst…”
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Does the prolonged in vitro maturation of human oocytes influence the aneuploidy type? by Lidija Križanič Bombek, Veljko Vlaisavljević, Borut Kovačič

“…Objective: In many stimulated infertility treatment cycles some oocytes are collected immature and can be matured in vitro (IVM). However, their safe clinical…”
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