Search Results - "Kreydiyyeh, Sawsan"
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Effect of FTY720P on lipid accumulation in HEPG2 cells
Published in Scientific reports (12-11-2023)“…Nonalcoholic fatty liver disease (NAFLD) is characterized by an increase in hepatic lipid accumulation due to impaired lipid metabolism. Although a correlation…”
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The signaling pathway through which Procyanidin B2 increases the activity of the Na+/K+ ATPase in Caco-2 cells
Published in Journal of functional foods (01-08-2024)“…[Display omitted] •In Caco-2 cells, Procyanidin B2 increased the activity of the Na+/K+ ATPase, which plays a key role in transport processes.•The stimulation…”
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3
PGE2 upregulates the Na+/K+ ATPase in HepG2 cells via EP4 receptors and intracellular calcium
Published in PloS one (01-01-2021)“…The Na+/K+ ATPase is a key regulator of the hepatocytes ionic homeostasis, which when altered may lead to many liver disorders. We demonstrated recently, a…”
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Epinephrine modulates Na+/K+ ATPase activity in Caco-2 cells via Src, p38MAPK, ERK and PGE2
Published in PloS one (21-02-2018)“…Epinephrine, a key stress hormone, is known to affect ion transport in the colon. Stress has been associated with alterations in colonic functions leading to…”
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Signaling Cascade Mediating the Effect of FTY720P on the Na+/K+ ATPase in LLC-PK1
Published in Cellular physiology and biochemistry (29-08-2022)“…Background/Aims: In renal ischemia, the Na+/K+ ATPase of the kidney epithelial cells translocates to intracellular compartments, resulting in altered kidney…”
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The epinephrine-induced PGE2 reduces Na+/K+ ATPase activity in Caco-2 cells via PKC, NF-κB and NO
Published in PloS one (08-08-2019)“…We showed previously an epinephrine-induced inhibition of the Na+/K+ ATPase in Caco-2 cells mediated via PGE2. This work is an attempt to further elucidate…”
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Influence of salinity on survival, growth, hemolymph osmolality, gill sodium potassium ATPase activity, and sodium potassium chloride co‐transporter expression in the redclaw crayfish Cherax quadricarinatus
Published in Journal of the World Aquaculture Society (01-04-2021)“…Abstract The Australian redclaw crayfish Cherax quadricarinatus is a freshwater crustacean aquacultured in many countries. Redclaw crayfish are often exposed…”
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Linalool decreases HepG2 viability by inhibiting mitochondrial complexes I and II, increasing reactive oxygen species and decreasing ATP and GSH levels
Published in Chemico-biological interactions (15-06-2009)“…Coriander is used as an appetizer, a common food seasoning in Mediterranean dishes, and a remedy for many ailments. In this study we tested the biochemical…”
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Insulin down-regulates the Na+ /K+ ATPase in enterocytes but increases intestinal glucose absorption
Published in General and comparative endocrinology (01-06-2010)“…Abstract The effect of insulin on [14 C] 3-O-methyl- d -glucose (3OMG) absorption in the rat jejunum was studied using an in situ perfusion technique. Insulin…”
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Pine bark extract inhibits glucose transport in enterocytes via mitogen-activated kinase and phosphoinositol 3-kinase
Published in Nutrition (Burbank, Los Angeles County, Calif.) (01-06-2011)“…Abstract Objective Pine bark extract (PBE) has been reported to have hypoglycemic effects but its mode of action is still unclear. This work studied the effect…”
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Leptin inhibits glucose intestinal absorption via PKC, p38MAPK, PI3K and MEK/ERK
Published in PloS one (10-12-2013)“…The role of leptin in controlling food intake and body weight is well recognized, but whether this is achieved by modulating nutrient absorption is still a…”
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Insulin targets the Na+/K+ ATPase in enterocytes via PI3K, PKC, and MAPKS
Published in Journal of receptors and signal transduction (01-08-2011)“…The effect of insulin on intestinal Na+/K+ ATPase is till now undetermined, and it is still unclear whether insulin exerts any modulatory effect on glucose…”
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Signaling pathway involved in the inhibitory effect of FTY720P on the Na+/K+ ATPase in HepG2 cells
Published in Journal of cell communication and signaling (01-12-2017)“…The Na + /K + ATPase modulates the activity of many transporters in the liver, and maintains the ionic constancy of the intracellular milieu, preserving thus…”
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Cow's milk may be delivering potentially harmful undetected cargoes to humans. Is it time to reconsider dairy recommendations?
Published in Nutrition reviews (10-03-2022)“…Mammalian evolution has shaped milk into a species-specific vehicle for post-natal development, continuing what began within the mother's womb. Increased…”
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Mediators of steatosis in HepG2 cells
Published in Physiology (Bethesda, Md.) (01-05-2023)“…Abstract only Hepatic lipid accumulation or steatosis has become nowadays a major public health problem. The disease can progress into serious liver damage…”
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The Appearance of a Leptin Effect on Glucose Absorption in Caco2 Cells Depends on Their Differentiation Level
Published in Cellular physiology and biochemistry (01-01-2015)“…Backdround/Aims: The aim of this work was to study the effect and mechanism of action of leptin added apically, on glucose absorption, using Caco-2 cells as a…”
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FTY720P inhibits the Na+/K+ ATPase in Caco-2 cells via S1PR2: PGE2 and NO are along the signaling pathway
Published in Life sciences (1973) (15-12-2018)“…Sphingosine-1-phosphate (S1P) has been implicated lately in inflammatory bowel disease which has diarrhea as one of its symptoms. Diarrhea is due to altered…”
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FTY720‐P Activates Hepatic Na + /K + ATPase via S1PR3, PKC and PGE 2
Published in The FASEB journal (01-04-2018)“…Abstract only Background Alterations in hepatocytes' volume contribute to the pathophysiology of several hepatic disorders including liver insufficiency,…”
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PGE2 and NO Mediate the Inhibitory Effect Exerted by FTY720P at 15 Minutes on Colonic Na+/K+ ATPase
Published in The FASEB journal (01-04-2018)“…Inflammatory Bowel Disease was shown to be accompaniedwith higher levels of sphingosine‐1‐ phosphate (S1P) and lower Na+/K+ ATPase activity. This work was…”
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FTY720P Increases, at 2 hrs, the Activity of the Na+/K+ ATPase in Caco‐2 cells via PKC and PI3K
Published in The FASEB journal (01-04-2018)“…Fingolimod phosphate (FTY720P), an analogue of sphingosine‐1‐phosphate (S1P), was shown previously to modulate, in a time‐dependent manner, the activity of…”
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