Search Results - "Kreuzman, A"

Monoclonal antibody capture and viral clearance by cation exchange chromatography by Miesegaes, G.R., Lute, S., Strauss, D.M., Read, E.K., Venkiteshwaran, A., Kreuzman, A., Shah, R., Shamlou, P., Chen, D., Brorson, K.

“…Traditionally, post‐production culture harvest capture of therapeutic monoclonal antibodies (mAbs) is performed using Protein A chromatography. We investigated…”
Get full text

Membrane-associated echinocandin B deacylase of Actinoplanes utahensis : purification, characterization, heterologous cloning and enzymatic deacylation reaction by KREUZMAN, A. J, HODGES, R. L, SWARTLING, J. R, POHL, T. E, GHAG, S. K, BAKER, P. J, MCGILVRAY, D, YEH, W. K

“…produces echinocandin B, a neutral lipopeptide. A deacylase from Actinoplanes utahensis catalyzes cleavage of the linoleoyl group from echinocandin B, a key…”
Get full text

Two distinctive O-methyltransferases catalyzing penultimate and terminal reactions of macrolide antibiotic (tylosin) biosynthesis. Substrate specificity, enzyme inhibition, and kinetic mechanism by Kreuzman, A J, Turner, J R, Yeh, W K

“…S-Adenosyl-L-methionine:demethylmacrocin O-methyltransferase catalyzes the conversion of demethylmacrocin to macrocin as the penultimate step of tylosin…”
Get full text

Purification, characterization, and kinetic mechanism of S-adenosyl-L-methionine:macrocin O-methyltransferase from Streptomyces fradiae by Bauer, N J, Kreuzman, A J, Dotzlaf, J E, Yeh, W K

“…S-Adenosyl-L-methionine:macrocin O-methyltransferase catalyzes conversion of macrocin to tylosin, the terminal and main rate-limiting step of tylosin…”
Get full text

Enzymatic synthesis of diastereospecific carbacephem intermediates using serine hydroxymethyltransferase by Kreuzman, A J, Zock, J M, Dotzlaf, J E, Vicenzi, J T, Queener, S W, Yeh, W K

“…The serine hydroxymethyltransferase (SHMT) gene glyA was over-expressed in Escherichia coli and the enzyme was purified to near homogeneity. Reaction…”
Get full text

Capillary electrophoretic analysis of serine hydroxymethyltransferase in Escherichia coli fermentation broth by Strege, M A, Schmidt, D F, Kreuzman, A, Dotzlaf, J, Yeh, W K, Kaiser, R E, Lagu, A L

“…Serine hydroxymethyltransferase (SHMT) expressed in Escherichia coli was analyzed in fermentation broth through the use of capillary electrophoresis (CE), a…”
Get more information

Discovery, purification, and properties of o-phthalyl amidase from Xanthobacter agilis by Briggs, Barbara S, Kreuzman, Adam J, Whitesitt, Celia, Yeh, Wu-Kuang, Zmijewski, Milton

“…A selective screen for organisms that would metabolize o-phthalyl protected beta-lactams resulted in the discovery of a Xanthobacter agilis strain that…”
Get full text

Novel Lipoglycopeptides as Inhibitors of Bacterial Signal Peptidase I by Kulanthaivel, Palaniappan, Kreuzman, Adam J, Strege, Mark A, Belvo, Matthew D, Smitka, Tim A, Clemens, Matthew, Swartling, James R, Minton, Kristina L, Zheng, Feng, Angleton, Eddie L, Mullen, Deborah, Jungheim, Louis N, Klimkowski, Valentine J, Nicas, Thalia I, Thompson, Richard C, Peng, Sheng-Bin

“…Signal peptidase (SPase) I is responsible for the cleavage of signal peptides of many secreted proteins in bacteria. Because of its unique physiological and…”
Get full text

Enzymatic synthesis of diastereospecific carbacephem intermediates using serine hydroxymethyltransferase: Microbial metabolism of aromatic hydrocarbons; a tribute to David T Gibson by KREUZMAN, A. J, ZOCK, J. M, DOTZLAF, J. E, VICENZI, J. T, QUEENER, S. W, YEH, W. K

Get full text

Selective deprotection of phthalyl protected amines by Costello, Colleen A., Kreuzman, Adam J., Zmijewski, Milton J.

“…Phthalyl amidase selectively deprotects phthalimido groups under very mild aqueous conditions in a one-pot reaction to produce phthalic acid and the free…”
Get full text