Search Results - "Kreutz, Barry"

Structure and function of the interacting domains of Spire and Fmn-family formins by Vizcarra, Christina L, Kreutz, Barry, Rodal, Avital A, Toms, Angela V, Lu, Jun, Zheng, Wei, Quinlan, Margot E, Eck, Michael J

“…Evidence for cooperation between actin nucleators is growing. The WH2-containing nucleator Spire and the formin Cappuccino interact directly, and both are…”
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Regulation of serum response factor-dependent gene expression by proteasome inhibitors by Sandbo, Nathan, Qin, Yimin, Taurin, Sebastien, Hogarth, D Kyle, Kreutz, Barry, Dulin, Nickolai O

“…Serum response factor (SRF) is activated by contractile and hypertrophic agonists, such as endothelin-1 (ET1) to stimulate expression of cytoskeletal proteins…”
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The interaction of Gα13 with integrin β1 mediates cell migration by dynamic regulation of RhoA by Shen, Bo, Estevez, Brian, Xu, Zheng, Kreutz, Barry, Karginov, Andrei, Bai, Yanyan, Qian, Feng, Norifumi, Urao, Mosher, Deane, Du, Xiaoping

“…Heterotrimeric G protein Gα13 is known to transmit G protein-coupled receptor (GPCR) signals leading to activation of RhoA and plays a role in cell migration…”
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Development of a new automated IL-6 immunoassay by Israeli, Eitan, Okura, Hideaki, Kreutz, Barry, Piktel, Ryan, Hadji, Abbas, Tu, Bailin, Lin, Zhihong, Hawksworth, David J., Tieman, Bryan C., Strobel, Carolyn J., Ziemann, Robert, Leary, Thomas P., Muerhoff, A. Scott, Hemken, Philip M.

“…Quantitative detection of interleukin-6 (IL-6) in serum and plasma can help monitor immune responses and the development of acute inflammation to guide patient…”
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Different Raf Protein Kinases Mediate Different Signaling Pathways to Stimulate E3 Ligase RFFL Gene Expression in Cell Migration Regulation by Gan, Xiaoqing, Wang, Chen, Patel, Maulik, Kreutz, Barry, Zhou, Maggie, Kozasa, Tohru, Wu, Dianqing

“…We previously characterized a Gα12-specific signaling pathway that stimulates the transcription of the E3 ligase RFFL via the protein kinase ARAF and ERK. This…”
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The 2.7‐Å crystal structure of Gα12 in complex with a regulator of G protein signaling homology (RH) domain (843.1) by Kreutz, Barry, Chanthavong, Dara, Santarsiero, Bernard, Kozasa, Tohru

“…Heterotrimeric G proteins Gα12 and Gα13 parse signals from G protein‐coupled receptors at the cell surface to activation of RhoA through a subset of…”
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VE-Cadherin Signaling Induces EB3 Phosphorylation to Suppress Microtubule Growth and Assemble Adherens Junctions by Komarova, Yulia A., Huang, Fei, Geyer, Melissa, Daneshjou, Nazila, Garcia, Alexander, Idalino, Luiza, Kreutz, Barry, Mehta, Dolly, Malik, Asrar B.

“…Vascular endothelial (VE)-cadherin homophilic adhesion controls endothelial barrier permeability through assembly of adherens junctions (AJs). We observed that…”
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Structural and Functional Analysis of the Regulator of G Protein Signaling 2-Gαq Complex by Nance, Mark R., Kreutz, Barry, Tesmer, Valerie M., Sterne-Marr, Rachel, Kozasa, Tohru, Tesmer, John J.G.

“…The heterotrimeric G protein Gαq is a key regulator of blood pressure, and excess Gαq signaling leads to hypertension. A specific inhibitor of Gαq is the…”
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The interaction of Gα 13 with integrin β 1 mediates cell migration by dynamic regulation of RhoA by Shen, Bo, Estevez, Brian, Xu, Zheng, Kreutz, Barry, Karginov, Andrei, Bai, Yanyan, Qian, Feng, Norifumi, Urao, Mosher, Deane, Du, Xiaoping

“…Heterotrimeric G protein Gα 13 is known to transmit G protein–coupled receptor (GPCR) signals leading to activation of RhoA and plays a role in cell migration…”
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Structural and Functional Analysis of the Regulator of G Protein Signaling 2-G[alpah subscript q] Complex by Nance, Mark R., Kreutz, Barry, Tesmer, Valerie M., Sterne-Marr, Rachel, Kozasa, Tohru, Tesmer, John J.G.

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Abstract 397: The Interaction of Integrin beta1 to Galpha13 Mediates RhoA Inhibition and Cell Migration by Shen, Bo, Estevez, Brian, Kreutz, Barry, Karginov, Andrei, Mosher, Deanne, Bai, Yanyan, Qian, Feng, Norifumi, Urao, Du, Xiaoping

“…Abstract only Background: Integrin-dependent cell migration is critically important in many physiological and pathological processes such as angiogenesis,…”
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VE‐cadherin Signaling Induces EB3 Phosphorylation to Suppress Microtubule Growth and Stabilize Adherens Junctions by Geyer, Melissa, Huang, Fei, Daneshjou, Nazila, Garcia, Alexander, Kreutz, Barry, Mehta, Dolly, Malik, Asrar B., Komarova, Yulia

“…Abstract only End Binding (EB) proteins, microtubule (MT) plus‐end factors, promote MT growth in cells. Here we demonstrate an unexpected role of Vascular…”
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A New Approach to Producing Functional Gα Subunits Yields the Activated and Deactivated Structures of Gα12/13 Proteins by Kreutz, Barry, Yau, Douglas M, Nance, Mark R, Tanabe, Shihori, Tesmer, John J. G, Kozasa, Tohru

“…The oncogenic G12/13 subfamily of heterotrimeric G proteins transduces extracellular signals that regulate the actin cytoskeleton, cell cycle progression, and…”
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A new approach to producing functional G alpha subunits yields the activated and deactivated structures of G alpha(12/13) proteins by Kreutz, Barry, Yau, Douglas M, Nance, Mark R, Tanabe, Shihori, Tesmer, John J G, Kozasa, Tohru

“…The oncogenic G(12/13) subfamily of heterotrimeric G proteins transduces extracellular signals that regulate the actin cytoskeleton, cell cycle progression,…”
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Distinct regions of Gα13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs by Kreutz, Barry, Hajicek, Nicole, Yau, Douglas M., Nakamura, Susumu, Kozasa, Tohru

“…Gα12 and Gα13 transduce signals from G protein-coupled receptors to RhoA through RhoGEFs containing an RGS homology (RH) domain, such as p115 RhoGEF or…”
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Activation of PLCβ by Gαi1/Gαq chimeras expressed by Sf9‐bacurovirus system by Kawano, Takeharu, Kreutz, Barry, Yau, Douglas M., Kozasa, Tohru

“…Gαq activates PLCβisozymes following stimulation of GPCR. DAG and IP3, which are produced from PIP2 by PLCβ, play crucial roles in intracellular signal…”
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Localization of the RhoGEF Effector Activating Surface of Gα 13 to its Carboxy Terminus by Hajicek, Nicole, Kreutz, Barry, Yau, Douglas, Nakamura, Susumu, Kozasa, Tohru

“…Abstract only…”
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Localization of the RhoGEF Effector Activating Surface of Gα13 to its Carboxy Terminus by Hajicek, Nicole, Kreutz, Barry, Yau, Douglas, Nakamura, Susumu, Kozasa, Tohru

“…The monomeric GTPase Rho regulates a variety of cellular processes, such as actin cytoskeletal rearrangement and gene expression. Two members of the…”
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RGS16 inhibits signalling through the Gα13-Rho axis by Druey, Kirk M, Johnson, Eric N, Seasholtz, Tammy M, Waheed, Abdul A, Kreutz, Barry, Suzuki, Nobuchika, Kozasa, Tohru, Jones, Teresa L.Z, Brown, Joan Heller

“…Gα13 stimulates the guanine nucleotide exchange factors (GEFs) for Rho, such as p115Rho-GEF. Activated Rho induces numerous cellular responses, including actin…”
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Distinct regions of Galpha13 participate in its regulatory interactions with RGS homology domain-containing RhoGEFs by Kreutz, Barry, Hajicek, Nicole, Yau, Douglas M, Nakamura, Susumu, Kozasa, Tohru

“…Galpha12 and Galpha13 transduce signals from G protein-coupled receptors to RhoA through RhoGEFs containing an RGS homology (RH) domain, such as p115 RhoGEF or…”
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