Search Results - "Kretz, Patricia L"
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Exploring Nitrilase Sequence Space for Enantioselective Catalysis
Published in Applied and Environmental Microbiology (01-04-2004)“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Cloning of the riboB locus of Aspergillus nidulans
Published in Gene (1987)“…We have complemented the riboB2 mutation of Aspergillus nidulans by transformation with a plasmid library of wild-type (wt) sequences. We have isolated, by…”
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The use of shuttle vectors for mutation analysis in transgenic mice and rats
Published in Mutation research (01-06-1994)“…The establishment in recent years of transgenic shuttle vector-based mutagenicity assays has provided improved systems for analysis of mutagenic and…”
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Spectra of Spontaneous and Mutagen-Induced Mutations in the lacI Gene in Transgenic Mice
Published in Proceedings of the National Academy of Sciences - PNAS (15-09-1991)“…Transgenic mice with a λ shuttle vector containing a lacI target gene were generated for use as a short-term, in vivo mutagenesis assay. The gene is recovered…”
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Development of a short-term, in vivo mutagenesis assay : the effects of methylation on the recovery of a lambda phage shuttle vector from transgenic mice
Published in Nucleic acids research (25-05-1990)“…Transgenic mice suitable for the in vivo assay of suspected mutagens at the chromosome level have been constructed by stable integration of a lambda phage…”
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The use of selection in recovery of transgenic targets for mutation analysis
Published in Mutation research (01-02-1993)“…Transgenic animal mutagenesis assays using lambda shuttle vectors have recently been described for isolation and characterization of spontaneous and chemical…”
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Transgenic systems for in vivo mutation analysis
Published in Mutation research (01-07-1993)“…Transgenic mice carrying shuttle vectors containing the lacI gene as the target permit the in vivo measurement of mutations in multiple tissues and have been…”
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A selectable system for mutation detection in the Big Blue lacI transgenic mouse system: what happens to the mutational spectra over time
Published in Mutation research (10-06-1996)“…Transgenic animals offer a powerful tool to study the mechanisms of spontaneous and induced mutagenesis in vivo. Herein we used a test version of a growth…”
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Spontaneous mutations in lacI-containing lambda lysogens derived from transgenic mice: the observed patterns differ in liver and spleen
Published in Mutation research (01-11-1994)“…The pattern of somatic mutation observed in tumor suppressor genes, such as the p53 gene, vary dramatically with tumor type. Some of the observed differences…”
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