Search Results - "Kretz, Julia"
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Clinical and genetic characteristics of BAP1 -mutated non-uveal and uveal melanoma
Published in Frontiers in immunology (05-06-2024)“…Screening for gene mutations has become routine clinical practice across numerous tumor entities, including melanoma. gene mutations have been identified in…”
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HLA Class II Loss and JAK1/2 Deficiency Coevolve in Melanoma Leading to CD4 T-cell and IFNγ Cross-Resistance
Published in Clinical cancer research (01-08-2023)“…Recent studies have demonstrated HLA class II (HLA-II)-dependent killing of melanoma cells by cytotoxic CD4 T cells. We investigated evolution of HLA-II-loss…”
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NF1-mutated melanomas reveal distinct clinical characteristics depending on tumour origin and respond favourably to immune checkpoint inhibitors
Published in European journal of cancer (1990) (01-12-2021)“…NF1-mutated tumours represent a small subset (10–15%) of melanomas, not sufficiently analysed in large clinical cohorts. This study investigated the largest…”
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Genetic and methylation profiles distinguish benign, malignant and spitzoid melanocytic tumors
Published in International journal of cancer (01-11-2022)“…Accurate classification of melanocytic tumors is important for prognostic evaluation, treatment and follow‐up protocols of patients. The majority of…”
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Clinical and pathological characteristics of familial melanoma with germline TERT promoter variants
Published in Pigment cell and melanoma research (01-11-2022)“…Around 10% of melanoma occurs in patients with a suspected familial predisposition. TERT promoter mutations are the most common somatic hotspot mutations in…”
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TERT promoter mutations are associated with longer progression-free and overall survival in patients with BRAF-mutant melanoma receiving BRAF and MEK inhibitor therapy
Published in European journal of cancer (1990) (01-01-2022)“…Around 50% of cutaneous melanomas harbour therapeutically targetable BRAF V600 mutations. Reliable clinical biomarkers predicting duration of response to…”
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Molecular pathology as a diagnostic aid in difficult-to-classify melanocytic tumours with spitzoid morphology
Published in European journal of cancer (1990) (01-05-2021)“…Accurate classification of melanocytic proliferations has important implications for prognostic prediction, treatment and follow-up. Although most melanocytic…”
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Abstract 1122‐000112: In Vitro Investigation of Endothelial Injury During Mechanical Thrombectomy for Ischemic Stroke
Published in Stroke: vascular and interventional neurology (01-11-2021)“…This meeting abstract was removed due to the OA licensing requirements of this journal. The full abstract is listed here :…”
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Genetic and Clinical Characteristics of ARID1A Mutated Melanoma Reveal High Tumor Mutational Load without Implications on Patient Survival
Published in Cancers (22-04-2022)“…(1) Background: Melanoma has the highest mortality of all cutaneous tumors, despite recent treatment advances. Many relevant genetic events have been…”
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Genetic and Methylation Analysis of CTNNB1 in Benign and Malignant Melanocytic Lesions
Published in Cancers (23-08-2022)“…Melanocytic neoplasms have been genetically characterized in detail during the last decade. Recurrent CTNNB1 exon 3 mutations have been recognized in the…”
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